Báo cáo khoa học: Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics docx

... 405–426. Characterization of glutaminyl cyclase isoenzymes A. Stephan et al. 6536 FEBS Journal 276 (2009) 6522–6536 ª 2009 Probiodrug AG. Journal compilation ª 2009 FEBS Mammalian glutaminyl cyclases and their isoenzymes have ... 2009) doi:10.1111/j.1742-4658.2009.07337.x Glutaminyl cyclases (QCs) catalyze the formation of pyroglutamate resi- dues at the N-terminus of se...

Ngày tải lên: 23/03/2014, 04:20

... –SO 3 PO 3 HNa. (A) Expanded view of peaks at m ⁄ z 2800.36 and 2832.35 and the fragmentation of the peak at m ⁄ z 2800.36. (B) Expanded view of peaks at m ⁄ z 2934.36 and 2950.35 and the fragmentation ... ubiquitous thiol-containing peroxidas- es that have been implicated in antioxidant defense and signal transduction. Although their biochemical features have been extensively...

Ngày tải lên: 18/02/2014, 17:20

... reduced and the cysteine residues alkylated in order to verify their identification. Although there are standard procedures for reduction and alkylation, their application to conopeptide analysis and ... to expand the diversity and utility of the pool of available a-conotoxins. Their identification andcharacterizationdependonasuiteoftechniques with increasing emphasis on mass spec...

Ngày tải lên: 19/02/2014, 12:20

... modeling and utterance classifica- tion (Saraclar and Roark, 2005) and labeling and chunking (Shimizu and Haas, 2006). Though our model is built specifically for Chinese word segmen- tation and POS ... joint segmentor and POS tagger. Acknowledgements We thank Hwee-Tou Ng and Mengqiu Wang for their helpful discussions and sharing of experimen- tal data, and the anonymous re...

Ngày tải lên: 20/02/2014, 09:20

... computers (or even PDAs) and uses a hand- held scanner to get the input material. In other words, TwicPen consists of (i) a simple hand-held scanner and (ii) parsing and translation software. TwicPen ... morphological and syntactic parser makes it possible (i) to disambiguate to a large extent the word selected by the user (and hence to drastically reduce the noise in the response),...

Ngày tải lên: 20/02/2014, 12:20

... coherence (e.g.,(Miltsakaki and Kukich, 2004), (Barzilay and Lapata, 2008), (Bruss et al., 2004), (Pitler and Nenkova, 2008)) can also be integrated after psy- cholinguistic evaluation studies are completed and their ... infor- mation retrieval system (Collins-Thompson and Callan, 2004) is based on web data that have been annotated and indexed off-line. Also, relatedly, (Schwa...

Ngày tải lên: 22/02/2014, 02:20

... expression segmentation and polarity labeling and compare them to the joint opinion extractor and polarity clas- sifier by Choi and Cardie (2010). Secondly, we ex- tend the global structure approach and add features reflecting ... points in intersection F-measure and 7 points in recall. The improvements over Choi and Cardie (2010) ranged between 10 and 15 in overlap F-measure a...

Ngày tải lên: 07/03/2014, 22:20

... and TmEcR were similar, as anticipated by their sequence similar- ity. In the PonA-bound HvEcR-LBD complex, the LBD is composed of 12 helices and three small b-strands, and possesses a long and ... [261], plant hormones and heat shock treatment have also been developed. Future studies EcR and USP (RXR) belong to the NR superfamily and have been identified in various insects...

Ngày tải lên: 23/03/2014, 04:20

... collect and purify SQAGs from natural sources but we have succeeded in the chemical synthesis of a number of forms. We have found a-anomers that possess potent antitumor activ- ity but do not have ... microtubles, SQAGs, and reaction components were mixed, and then were incubated at 24 °C for 30 min. The reaction mixture was centrifuged at 223 000 g and the supernatant and the...

Ngày tải lên: 19/02/2014, 17:20

... structures, mechanisms and [2Fe-2S] clus- ters. Cell Mol Life Sci 57, 1909–1926. 6 Taketani S (2005) Aquisition, mobilization and utiliza- tion of cellular iron and heme: endless findings and growing evidence ... of cytochrome oxidase are phosphorylated both in vivo and in vitro [12]. NADH dehydrogenase and pyruvate dehydrogenase are phosphorylated and their activities are chan...

Ngày tải lên: 16/03/2014, 00:20