Báo cáo khoa học: Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles pot
... iodine vapour. The
position of GM1 is indicated on the right of
the plate. Lipids migrated as multiple bands
on the HPTLC plate because of the hetero-
geneity of the fatty acyl chains of the ... domain (cytosolic tail, transmembrane
domain and few amino acids of the stem region) of Gal-
NAc-T fused to the N-terminus of YFP (GalNAc-T-YFP)
was obtained by s...
... 5689–5702 ª 2009 The Authors Journal compilation ª 2009 FEBS
Suppression of nuclear factor-jB activity in macrophages
by chylomicron remnants: modulation by the fatty acid
composition of the particles
Clara ... factor
nuclear factor-jB (NF-jB) has been implicated. In this study, the in uence
of CMR on the activity of NF-jB in macroph...
... a linearized plasmid containing a 553-bp
fragment of b3Gal-T5 cDNA, that includes the initial
360 bp of the coding sequence and 192 bp of the 5¢
untranslated region of the gene, placed in the ... obtained by Bio-
Gel P-4 purification of the included volume of the column in (A), large
O-glycans (j), obtained as the included volume of the column in (C),
an...
... 5¢-side of the
processing stem, gave rise to rRNA with the majority
of termini in the mature form, whereas pD3, with a
mutation on the 3¢-side, gave rise rRNA with the
majority of the termini in the ... rRNA termini are present in both
the 50S and the 70S fractions
We then investigated whether the observed extended
termini present in the 23S processing stem...
... Western blotting showed that the
FOXO1 content decreased in the cytoplasm but
increased in the nucleus. In contrast, the level of PDX-1
increased in the cytoplasm but decreased in the nucleus
(Fig. ... cells
induced by d-glucose.
Suppression of NOX2 substantially restores
D-glucose-induced dysfunction and apoptosis of
NIT-cells
To investigate the potential ro...
... treatment resulted in an increase in the number of
binding sites and a decrease of the affinity of the uPAR
[38,39]. The quantification of uPAR expression by mea-
surement of the amount of uPA bound ... through suppression of upstream
targets of ERK. Thus, one of the functions of bikunin is the
regulation of uPA synthesis and uPA binding by modulat-...
... resulting in the formation of the kinetochore
fibre, leads to a reduction in the concentration of the
motor proteins and spindle checkpoint proteins [19].
This reduction of checkpoint proteins is ... FEBS
Activation of the spindle checkpoint protein
BubR1 by benomyl treatment
To investigate the status of the checkpoint protein
BubR1 following benomyl treatment, we...
... of the expression of
hsps differed depending on the drug.
Induction of thermotolerance of cells by IND
As IND and NDGA caused hsps to accumulate in
mammalian cells, we next examined whether these ... temperature that is otherwise
insufficient. In contrast, IND induces the expression of
Hsp70 in human umbilical vein endothelial cells [18] or
induces the nuclear local...
... fluctuations in the levels of blood glucose [13], fatty
acids [12,14,15] and certain amino acids [16].
A linkage between fatty acid synthesis in the CNS
and feeding behavior was uncovered with the finding
that ... directed
into the fatty acid synthesis pathway. Glucose metabo-
lism in the CNS en route to fatty acids gives rise to
ATP and NADH, and inhibits isocitra...
... ddition of
penicillamine and cysteine to form a disulfide bond will
increase the number of amino acids in the peptide. The
information obtained from truncating the peptides will
also be useful in the ... of b-turn in CD2 protein. In addition, the
binding sites of the peptides to CD58 protein predicted by
autodock were near the CD2–CD58 interface, either in...