Báo cáo khoa học: Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles pot

... iodine vapour. The position of GM1 is indicated on the right of the plate. Lipids migrated as multiple bands on the HPTLC plate because of the hetero- geneity of the fatty acyl chains of the ... domain (cytosolic tail, transmembrane domain and few amino acids of the stem region) of Gal- NAc-T fused to the N-terminus of YFP (GalNAc-T-YFP) was obtained by s...

Ngày tải lên: 16/03/2014, 04:20

... 5689–5702 ª 2009 The Authors Journal compilation ª 2009 FEBS Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles Clara ... factor nuclear factor-jB (NF-jB) has been implicated. In this study, the in uence of CMR on the activity of NF-jB in macroph...

Ngày tải lên: 23/03/2014, 04:20

... a linearized plasmid containing a 553-bp fragment of b3Gal-T5 cDNA, that includes the initial 360 bp of the coding sequence and 192 bp of the 5¢ untranslated region of the gene, placed in the ... obtained by Bio- Gel P-4 purification of the included volume of the column in (A), large O-glycans (j), obtained as the included volume of the column in (C), an...

Ngày tải lên: 19/02/2014, 12:20

... 5¢-side of the processing stem, gave rise to rRNA with the majority of termini in the mature form, whereas pD3, with a mutation on the 3¢-side, gave rise rRNA with the majority of the termini in the ... rRNA termini are present in both the 50S and the 70S fractions We then investigated whether the observed extended termini present in the 23S processing stem...

Ngày tải lên: 06/03/2014, 00:21

... Western blotting showed that the FOXO1 content decreased in the cytoplasm but increased in the nucleus. In contrast, the level of PDX-1 increased in the cytoplasm but decreased in the nucleus (Fig. ... cells induced by d-glucose. Suppression of NOX2 substantially restores D-glucose-induced dysfunction and apoptosis of NIT-cells To investigate the potential ro...

Ngày tải lên: 06/03/2014, 02:20

... treatment resulted in an increase in the number of binding sites and a decrease of the affinity of the uPAR [38,39]. The quantification of uPAR expression by mea- surement of the amount of uPA bound ... through suppression of upstream targets of ERK. Thus, one of the functions of bikunin is the regulation of uPA synthesis and uPA binding by modulat-...

Ngày tải lên: 17/03/2014, 11:20

... resulting in the formation of the kinetochore fibre, leads to a reduction in the concentration of the motor proteins and spindle checkpoint proteins [19]. This reduction of checkpoint proteins is ... FEBS Activation of the spindle checkpoint protein BubR1 by benomyl treatment To investigate the status of the checkpoint protein BubR1 following benomyl treatment, we...

Ngày tải lên: 30/03/2014, 10:20

... of the expression of hsps differed depending on the drug. Induction of thermotolerance of cells by IND As IND and NDGA caused hsps to accumulate in mammalian cells, we next examined whether these ... temperature that is otherwise insufficient. In contrast, IND induces the expression of Hsp70 in human umbilical vein endothelial cells [18] or induces the nuclear local...

Ngày tải lên: 30/03/2014, 15:20

... fluctuations in the levels of blood glucose [13], fatty acids [12,14,15] and certain amino acids [16]. A linkage between fatty acid synthesis in the CNS and feeding behavior was uncovered with the finding that ... directed into the fatty acid synthesis pathway. Glucose metabo- lism in the CNS en route to fatty acids gives rise to ATP and NADH, and inhibits isocitra...

Ngày tải lên: 14/02/2014, 22:20

... ddition of penicillamine and cysteine to form a disulfide bond will increase the number of amino acids in the peptide. The information obtained from truncating the peptides will also be useful in the ... of b-turn in CD2 protein. In addition, the binding sites of the peptides to CD58 protein predicted by autodock were near the CD2–CD58 interface, either in...

Ngày tải lên: 19/02/2014, 13:20