Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
... Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages Jin-Sik Kim 1 *, Seungeun Yeo 1 *, Dong-Gu Shin 2 , ... of the Nox1 expression mechanism in macro- phages. Reports show that IRAK -1 increases Nox1 expression to produce ROS [ 21] , and the increase in Nox...
Ngày tải lên: 22/03/2014, 21:21
... pro- teins Rac1 and Cdc42 to the c-Jun N-terminal kinase/ stress-acti- vated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase ... MAPKKK, MAPKK kinase; MUK, MAPK-upstream kinase; DLK, dual leucine zipper-bearing kinase; IjB, inhibitor of NF-jB; MBIP1, MUK-binding inhibitory protein 1; IKK, IjB k...
Ngày tải lên: 17/03/2014, 09:20
... Liao, Institute of Biochemistry and Cell Biology, 320 Yueyang Road, Shanghai 2000 31, China Fax: +86 21 549 210 11 Tel: +86 21 549 211 13 E-mail: kliao@sibs.ac.cn (Received 11 March 2009, revised 16 November ... PPARc regulates the expression of genes involved in lipid metabolism [19 ]. Besides its function in adipogenesis, PPARc is also implicated in leptin-induced adipoc...
Ngày tải lên: 16/02/2014, 09:20
Báo cáo khoa học: A novel prokaryotic L-arginine:glycine amidinotransferase is involved in cylindrospermopsin biosynthesis potx
... streptomy- cin in the soil bacterium Streptomyces griseus [ 31] , and l-arginine:glycine amidinotransferase (EC 2 .1. 4 .1) involved in creatine biosynthesis in vertebrates [26]. In cylindrospermopsin biosynthesis, ... JB (19 75) L-arginine:inosamine-P amidinotrans- ferase(s). Methods Enzymol 43, 4 51 458. 41 Fritsche E, Humm A & Huber R (19 97) Substrate bind- ing and cat...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Trehalose synthase converts glycogen to trehalose pptx
... = 41 50; B = 51 –60; C = 61 70; D = 71 80; E = 81 90; F = 91 10 0; G = 10 1 11 0; and H = 11 1 12 0. An aliquot of each pooled fraction was subjected to SDS ⁄ PAGE (Fig. 2) and MTase activity and ... 80 91 0 .1 ( +1. 9 glucose) 14 .6 30.9 13 .4 14 .5 14 .6 2.0 340.4 18 7.4 315 .1 4.2 12 .9 4.0 513 .9 369.5 316 .5 6.8 11 .1 Presence of TreS in cells +++)) Table 6. Effect o...
Ngày tải lên: 16/03/2014, 06:20
Tài liệu Báo cáo khoa học: Insulin/protein kinase B signalling pathway upregulates metastasis-related phenotypes and molecules in H7721 human hepatocarcinoma cell line pptx
... Delcommenne,M.,Tan,C.,Gray,V.,Rue,L.,Woodgett,J.& Dedhar, S. (19 98) Phosphoinositide-3OH. kinase- dependent regulation of glycogen synthetase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc. Natl Acad. Sci. USA 95, 11 211 11 216 . 9. Krasilnikov, ... as receptor protein tyrosine kinase/ growth factor receptor binding protein 2-son of sevenless protein/Ras/Raf...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx
... addi- tional mutations D101N and R183K in the SH3 and SH2 domains (Fig. 1D and Table 1) . Previous studies [3 ,18 – 21] have shown that D99 (corresponding to D1 01 in n-Src) in the SH3 domain of c-Src forms ... USA Fax: +1 850 644 57 81 Tel: +1 850 645 2 718 E-mail: xianmin.yu@med.fsu.edu (Received 10 September 2 010 , revised 3 November 2 010 , accepted 6 December 2 010 )...
Ngày tải lên: 06/03/2014, 01:20
Báo cáo khoa học: NO synthase isoforms specifically modify peroxynitrite reactivity pptx
... into N x -hydroxy-l-arginine [10 ]. The second step, specific to NOSs, converts N x -hydroxy-l-arginine into citrul- line, with NO being formed as a by-product [11 ,12 ]. This subtly regulated mechanism [13 ] is shared ... (19 97) Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding. Bio- chemistr...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Phytoene synthase genes in tomato (Solanum lycopersicum L.) – new data on the structures, the deduced amino acid sequences and the expression patterns doc
... 15 22 412 45.32 62 38.50 Psy2 11 2 710 51 173 236 19 3 19 9 15 3 10 7 710 273 227 398 3542 338 13 17 19 16 74 438 48 .18 86 38.72 a Exons 1 and 7 were only partially sequenced as well as the 5¢- and 3¢-UTRs. b Predicted ... (nt) a Protein Exon Intron Length 5¢-UTR CDS 3¢-UTR Length Integral cTP b Mature 12 3456 712 3456 Amino acids kDa Amino acids kDa Psy1 32 656 51 173 236...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor f chain by the protein tyrosine kinase Lck potx
... phosphotyro- sine-containing peptides was determined at 267 nm using molar absorption coefficients of 652 M )1 Æcm )1 for phospho- tyrosine [14 ] and 14 27 M )1 Æcm )1 for tyrosine [15 ]. Gene cloning, protein ... phosphorylated after 30 min (± SD) n ¼ 3 1N 5 & 5–6 65.9 (± 7.6) 1C 6–8, 7–9 & 7–9 12 .7 (± 2.8) 2N 12 14 & 12 15 19 .9 (± 9.3) 2C 16 17 19 .0 (± 9.3) 3N...
Ngày tải lên: 08/03/2014, 02:20