Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue pdf

... RESEARCH ARTICLE Open Access Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue Mariëtte Lokate 1 , Petra HM Peeters 1,4 , ... area of dense and fat tissue. Conclusions: Fibroglandular and breast fat tissue have indepe ndent effects on breast cancer risk. The results indicate that the n...

Ngày tải lên: 22/03/2014, 17:20

... them into account. Together, these results support the hypothesis of an age-specific effect of the three breast cancer risk factors considered herein, based on the time of initiation of the ... direction of the association, that is whether the risk of cancer increases or decreases with exposure, but also allow estimations of the magnitude of the effec...

Ngày tải lên: 05/03/2014, 17:20

... on the risk of a breast cancer only when the cancer was diagnosed after age 50. The change in the slope of the curve showing the age-specific incidence of breast cancer around the age of 50 ... on breast cancer risk. However, the relationship between these factors and the risk of breast cancer varied according to the age at breast cancer d...

Ngày tải lên: 28/03/2014, 16:20

... 1996 vaccination. These developments have prompted a re-evaluation of the role of BCG vaccination in the prevention and control of TB in the United States. CDC, the Advisory Council for the Elimination of Tuberculosis ... Control and Prevention. The role of BCG vaccine in the pre- vention and control of tuberculosis in the United States: a joint statement...

Ngày tải lên: 15/02/2014, 13:20

... Na + and Cl – [1]. The main physiological function of the transporter is believed to be the control of the concentration and dwell time of GABA in the synaptic cleft. Because the transport of one ... in the regulation of the stability and trafficking of GAT1. It has been reported that a variety of molecular chaperones and folding enzymes assist the foldi...

Ngày tải lên: 19/02/2014, 17:20

... distortion of the )1 sugar and by increasing the pK a of the catalytic acid. The hydroxyl group of Tyr214 makes a major contribution to the positioning of the N-acetyl group of the )1sugar.Taken together, ... 257 rows 5 and 7 shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pK a of the latter by 0.8 pH units....

Ngày tải lên: 07/03/2014, 14:20

... Stereo figures of the model of the bound substrate in the AD2 E526A mutant (A) and D524A mutant (B). The structures of bound sugars and the side-chains of three acidic residues in the conserved ... causes the distortion and twist- ing of the substrate, so that the glycosidic oxygen faces towards the bottom of the deep cleft. Enzyme–substrate interactions...

Ngày tải lên: 15/03/2014, 11:20

... using the c oncen tration of protein in the extract as an internal standard. The activity of ()119/+178) PS1CAT in the pres- ence of the empty vector was taken as 100%. The values represented in the ... Similarity in the processing of APP a nd the Notch receptor protein, which controls signaling and cell–cell communication in development, have largely contributed t...

Ngày tải lên: 16/03/2014, 18:20

... investors at the prices they offer through their outlets, and provide depositing and clearing services to the investors. B. Roles of the government and the central bank in bond market development The ... summary, the rapid growth of M2/GDP ratio is the consequence of financial deepening and a reflection of the unique feature of the structure of financial...

Ngày tải lên: 18/10/2013, 07:15

... Charts 3-5, the size categories are not adjusted for inflation and are based on the size of the bank rather than the size of the banking organization. 6 An alternative measure of profitability ... December. Berger, Allen N., and Gregory F. Udell. 1998. The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth...

Ngày tải lên: 16/02/2014, 11:20