Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx

... displaying protection compatible with a cross-b conformation [59 ,61,62]. High resolution information on the confor- mation of proteins in the aggregated state can be obtained by solid-state NMR, a ... [66]. These two independent observations confirm that the content of the bacterial cytoplasm can support the formation of infectious con- formations and suggest that bacteri...

Ngày tải lên: 06/03/2014, 00:20

... cascade that recruits an ADP-ribosylation factor 6 guanine nucleotide exchange factor (such as ARNO) to the apical plasma mem- brane. ARNO facilitates ADP-ribosylation factor 6 activation at the ... HXA 3 may play an important step underly- ing the pathophysiology of in ammatory diseases, such as in ammatory bowel disease, the investigation of human 12-LOX genes at mucosal...

Ngày tải lên: 19/02/2014, 02:20

... words, called biphrases, as building blocks for translations, and score alternative candidate trans- lations for the same source sentence based on a log-linear model of the conditional probability ... optimize the search by taking ad- vantage of highly unambiguous and informative portions that should be best translated far from the beginning. All these reasons motiv...

Ngày tải lên: 20/02/2014, 07:20

... Corporation, American Fork, UT, USA). The scan rate was 2 ° CÆmin )1 and there was a delay of 5 min between sequential scans in a series to allow for thermal equilibration. The features of the ... K, Jacob J & Cafiso DS (1999) Interactions con- trolling the membrane binding of basic protein domains: phenylalanine and the attachment of the myristoylated alanine-ric...

Ngày tải lên: 07/03/2014, 17:20

... at a flow rate of 450 lLÆmin )1 with 90% A and 10% B for 5 min, to 5% A and 95% B within 10 min, then increasing the flow rate to 900 lL within 2 min and maintaining these final conditions for 5 ... substrates indicates that the preference for each of the cleavage positions is determined by the hydroxyl- ation and the nature of the ionone ring. The data o...

Ngày tải lên: 15/03/2014, 23:20

... target domain data was divided into two folds. One fold was set aside for testing and the other for injecting data in the adaptation setting. We increased the size of the injected target examples ... adapta- tion scenarios. The fact that nearly 50 -60% of the words fall in the “conformist” category once again makes a strong case for reusing sense tagged data from...

Ngày tải lên: 17/03/2014, 00:20

Ngày tải lên: 08/03/2014, 01:20

... suggests that calpain 7 also functions as a protease rather than as a structural protein in mamma- lian cells, and that MIT domains are involved in cal- pain 7 activation. This notion leads us to ... domain and is classified as an atypical calpain. As one of the significant structural features, mammalian calpain 7 possesses a tandem repeat of microtubule-interacting and...

Ngày tải lên: 18/02/2014, 04:20

... mannanase from Bacillus circulans (accession no. BAA 258 78.1) [31]. Protein 7b was identified as the mannanase Man2 6A [14]. Lastly, protein 13 was identified as an N-terminal dockerin-borne chagasin ... chromatography in a tandem mass spectro- meter. Peptides were loaded onto a strong cation-exchange column and eluted in salt steps with an increasing ammonium acetate molari...

Ngày tải lên: 18/02/2014, 08:20

... and molecular mass analyses. The activity at saturating conditions was similar before and after dilution, incubation and storage. Native molecular size The apparent molecular size was determined ... Discussion Identification of the group inducing tetramerization of human TK1 Human TK1 has 234 amino acids and a subunit size of 25. 5 kDa [18]. Several reports have shown by...

Ngày tải lên: 18/02/2014, 12:20