Báo cáo khoa học: Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa potx

... clustering but on understanding the expression of intent. 3 Method We address the main thesis of the work by retrospec- tively studying queries issued to a search engine over the course of 12 ... cause, given that there is an increased use of Q-queries in spite of the seem- ingly inferior search results, there is a strong need for the search engines to improve their ha...

Ngày tải lên: 17/03/2014, 00:20

... resides on the surface of the protein and makes no obvious stabilizing interactions with other amino acid side- chains, this part of the protein interacts with genomic RNA [33,41,47]. Such interactions ... promote significant binding of bis-ANS to any of the particles, with the exception of T45S, which bound a small amount of bis-ANS, increasing, by twofold, the e...

Ngày tải lên: 19/02/2014, 12:20

... for the definitions). The fourth column depicts the levels of discourse segments which are com- puted by the algorithm in Table 6. Horizontal lines in- dicate the beginning of a segment (in the ... thus intends to extend the scope of centering in ac- cordance with cognitively plausible limits of the atten- tional span. Walker, finally, claims that the co...

Ngày tải lên: 22/02/2014, 03:20

... beginning of the word until the onset of the vowel feature and the alveolar feature would be defined as commencing at the end of the vowel feature and ending at the end of the word. Of course, ... alternation defined as an alternation in the value of the voicing feature. The voicing feature of the set of verbs we are talking about is altered if...

Ngày tải lên: 09/03/2014, 01:20

... cysteines. In conclusion, we show a mechanism of action of bacitracin on PDI that involves covalent binding of an open thiol form of bacitracin to free cysteines in the substrate-binding domain of ... [16] tested the effect of bacitra- cin on the reductive activity of a truncated PDI con- taining the catalytic a-domain, but lacking the independent substrate-binding...

Ngày tải lên: 14/03/2014, 23:20

... overexpressing the EVH1 domain. These results indicate that the EVH1 intrabodies inhibit only the EVH1 domain function that regu- lates IL-2 synthesis signaling without affecting the overall domain structure of ... consisting of V H and V L regions with ⁄ without the V H leader sequence at the N-terminal and with ⁄ without the C L (j) region behind the V L region. None...

Ngày tải lên: 16/03/2014, 14:20

... reminiscent of debugging assembly language progranuuing in hex". Considering that the (linguistic) user is interested in the rules rather than in the low-level implementation of them, ... derivation and compounding. The following constructor would build representations of all French verbs of the regular er-paradigm in the infinitive, including the info...

Ngày tải lên: 18/03/2014, 02:20

... of 3.2) [45] was a solution in the Dali result. It is likely that the inte rface between N-terminal and b-he lical domains participate in binding of the polysaccharide, pullulan. Comparison of ... is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study are shown in Fig. 3. To elucidate the mechanism of...

Ngày tải lên: 19/02/2014, 16:20

... Examination of 50% of the data in the SLs leads to identification of between 75% (AdjN) and 80% (PNV) of the TPs. (ii) For the first 40% of the SLs, and lead to the worst results, with outperforming ... mixed; (ii) the grammatical status of the individual word combinations in the base set, i.e., whether they are part of or constitute a phrase or simply co-...

Ngày tải lên: 20/02/2014, 18:20

... exchange of the H A -hydrogen of IPP. In both cases, scrambling of the label takes place within the IPP pool and the error is then transcribed into the DMAPP pool by the normal action of the isomerase. ... accounting for the known lack of fidelity of IPP isomerase. The resulting isotopic scrambling can be visualized by following the fate of the C atom labe...

Ngày tải lên: 22/02/2014, 07:20