... analysis of protein unfolding The DSC curves of the wild-type protein and the mutants K133A, E142O, W140A and W140O are shown in Fig. 3, with their thermodynamic parameters summarized in Table 1. The ... significant role in maintaining SNase tertiary structure. Our CD and DSC data show that the W140 in SNase is the amino acid responsible for the stability...
Ngày tải lên: 20/02/2014, 01:20
... hese conditions, by t he presence of a protein band with a slower mobility (lane 3, *) occurring within the a s complex. As the a s1 -Cas and a s2 -Cas overlap in the same zone of the gel, the ... a s1 -CasA and B variants, must be considered a ‘strong’ variant, given the intensity of the isoelectrofocusing bands and the surface of the relevant peak in...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo khoa học: "A Multimodal Interface for Access to Content in the Home" pdf
... understanding of system capa- bilities. Of the remaining 66% of inputs (2166) which were within the functionality of the system, 68% were in grammar. On the within functionality portion of the ... completing the same two sets of scenarios and then freely interacting with each system. For counterbalancing purposes, half of the subjects used the tablet...
Ngày tải lên: 20/02/2014, 12:20
Báo cáo " A new Environmental Poverty Index (EPI) for monitoring system in the SEA (Strategic Environmental Assessement) procedure " docx
... is the value of the indicator i in the year t; Vp is the prospective value of the indicator i of the last year of the plan (minimum value). The UNDP ’ s HPI is an indicator of poverty in ... which I it is the sectoral indicator number i in the year t; Vo is the value of the indicator i in the beginning (starting) year of the plan, sele...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo khoa học: Evidence for two different electron transfer pathways in the same enzyme, nitrate reductase A from Escherichia coli potx
... four kinetic phases in the reduction of the hemes by menaquinol. According to the quinone type used, the two hemes of the cytochrome are probably involved in the transfer of electrons from the ... which seems to indicate that the reduction of the hemes of the cytochrome varies according to the analogue of quinone used, and in neither case is it comple...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot
... decrease in the level of adenine nucleotides and a concomitant increase in the level of inosine. A plausible explanation of the effect of H 2 O 2 as inhibitor of glycolysis is presented. Materials and ... both processes could affect the actual concentration of ATP and hence the rate of synthesis of inosine. It is here assumed that the complex processes o...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: Distinct but critical roles for integrin aIIbb3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin pot
... integrin activation, in view of the critical role of integrins in mediating adhesion and cell spreading. To address this, experiments were designed to compare the role of the major platelet integrin ... as ‘inside-out’ signalling) promote a conformational change in the extracellular domain, leading to an increase in affinity, thereby promoting integrin–ligand intera...
Ngày tải lên: 16/03/2014, 12:20
BÁO CÁO " MỘT CÁCH TIẾP CẬN ĐỘ TIN CẬY TRÊN CƠ SỞ CHUYỂN ĐỔI TỪ ĐẠI LƯỢNG MỜ SANG ĐẠI LƯỢNG NGẪU NHIÊN " pptx
... nguyên lý thông tin không đầy đủ (insufficient reason). Trong [13] Klir đã kiến nghị chuyển đổi từ đại lượng mờ sang đại lượng ngẫu nhiên theo nguyên lý bất định bất biến (uncertainty invariance). ... đó. Do đó, mức độ an toàn SP xác định theo [3] có thể xem là tương đương với độ tin cậy P s theo định nghĩa ở mô hình ngẫu nhiên. Để đưa cách tính độ tin cậy trở về mô hình ngẫu nhiên, bài...
Ngày tải lên: 19/03/2014, 17:20
Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
... risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they are the only animals that pass oocysts in their feces. They become infected by eating infected rodents, ... parasite in its feces (approximately 2% of the cat population at any given time) contaminates the litter box. If the cat is allowed outside, it can contaminate the so...
Ngày tải lên: 03/11/2012, 11:06
Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc
... is under the direct control of kinases and phosphatases, and the indirect control of phosphorylation through the regula- tion of other apoptotic proteins. Furthermore, many kinases and phosphatases ... depend on the kinases ⁄ phosphatases involved and the effect of upstream proteins. Even with the same outcome, a wide range of signaling transduction factors a...
Ngày tải lên: 14/02/2014, 22:20