... heterogeneity in the cutaneous expression of elements of the serotoninergicpathway. Therefore, we have tested the expression of dif-ferent elements of the serotoninergic system in the C57BL/6 ... addi-tion of the MAO inhibitor, pargyline, blocked production of these compounds. This indicates that serotonin degrada-tion in the skin includes its oxidative deamination. The H2O2produced during ... for the oxidation of serotonin and other indoleamines, similarto the intestinal metabolism of tyramine [45].NAS metabolism was extensive and hair cycle-dependent in mouse back skin, producing...