... inhibitory effect [4]. Therefore, the aim of the present work was to investigate the mode of action of the toxin, as part of a wider study to determine whether PA1bcould be a valuable tool for ... fraction of Sitophilusextract In order to determine the fate of the labeled toxin during the binding test, the 125I-labelled PA1b ligand was incubated for 5hwith5lg of proteins of the microsomal ... probably the molecular target of the toxin, and that resistance within the S. oryzae species potentially involves a variation in thisprotein. However, the role of the binding protein in insects,and...