... resulted in the amplification of nucleotide regions 653 –964, 52 4–784, 56 2– 858 , and 36 75 50 69 for HPV8(NC_00 153 2), HPV10 (NC_00 157 6), HPV16 (NC_00 152 6),and Slit1 (Q80TR4), respectively. In the database, ... at the extremity of the sixth b-strand (Fig. 5A), raising the possibility of the formation of an intermolecular disul-fide bridge between the PDZ domain and its targetpeptide, similar to the ... mutated the Cys 157 5 residue (amino acid numbering according toAccession no. NP_0 353 34) to serine and tested the binding abilities of the resulting GST–PDZ3(C 157 5S)fusion protein. Intriguingly, the...