Báo cáo Y học: S-Decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1) ppt
Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"
... other studies [4-6] because of activity against key pathogens. Consideration of the influence of appro- priateness of empiric therapy against subsequently identi- fied pathogens was beyond the ... initial antibiotic therapy is vital because delayed treatment is associated with increased risk of mortality [4,10-15]. The choice of therapy depends on the presence of risk...
Ngày tải lên: 25/10/2012, 10:02
Báo cáo y học: "Surgical and medical emergencies on board European aircraft: a retrospective study of 10189 cases"
... analysis, which included the frequency and type of emergency. The frequency of aircraft diversion was also investigated. All data regarding names, ages and the sex of the patient and the name of ... writing of the manuscript. FGB participated in the data analysis and interpretation of the study. DS participated in the data analysis, literature search, revision o...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "980 nm diode lasers in oral and facial practice: current state of the science and art"
... the suggestions of scientific literature on the advantages of the compactness, reliability, ease of use and affordability of the 980 nm Diode Lasers, we evaluated the efficacy and safety of ... Diseases, Unit of Dermatology, University of Bari, Italy Correspondence to: Dr. Andrea BALLINI, PhD., Department of Dental Sciences and Surgery, University of Bari, Bar...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: " A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women"
... at the disposal of the researchers during the test period for any unexpected circum- stances. Upon completion of the study, the envelope was opened in the presence of a representative of the ... and/or slowing the breakdown of complex carbohydrates, thereby reducing the diges- tive availability of carbohydrate-derived calories, at least early on, and/or favor...
Ngày tải lên: 31/10/2012, 15:12
Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot
... K + for activity [34,37], while the lemon enzymes are inhibited by potassium ions. The pH optimum of the lemon synthases is close to pH 7 like other angiosperm synthases, while the gymnosperm synthases ... caused by product inhibition as the products of the synthases will migrate to the hexane phase used in the assays and are therefore not expected to be interfering with...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
... in CnB to the active site [22]. In fact, the catalytic activity of CaN is sensitive to the amino-acid composition of the region linking the CnB-binding helix to the b14 strand of the catalytic core ... previously reported [23,37]. Differences in CaN preparations and methods of enzyme activity assays may account for the differences in IC 50 values. For these studies...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... GST–cyto -Y5 97F (Y! F mutation at the 597 position), GST– cyto -Y6 41F (Y! F mutation at the 641 position), GST– cyto -Y6 67F (Y !F mutation at the 667 position), GST– cyto -Y6 91F (Y! F mutation at the ... significantly affect the degree of phosphorylation by any of the kinases that were tested. In addition, a construct containing Y6 41 alone was not phosphorylated by any...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis ppt
... of (His) 6 PNAE. After they were individually replaced by alanine, the activity of the enzyme was lost completely (Table 2). With the Cys muteins, the results were variable. After mutating Cys213 ... activity, and in the case of Cys170, the decrease in the specific activity was even greater (approx. sevenfold). The exchange of Cys20 resulted in the total inactiva...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Conditionally immortalized adrenocortical cell lines at undifferentiated states exhibit inducible expression of glucocorticoid-synthesizing genes pot
... pat- terns of the steroid 1 1b-hydroxylase P45011b gene respon- sible f or the zone-speci®c s ynthesis of corticosterone. AcA201 cells expressed the P45011b gen e at 33 °C, showing the property of the ... with amounts of wild-type T-antigen at 37 °C. It is presumable that levels of the ts T-antigen protein are very low at body temperature. At 33 °C, on the other hand,...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo khoa học: EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine⁄threonine kinases and phosphatase in Mycobacterium tuberculosis doc
... analyzed. While purified EmbR showed an ATPase activity of 0.040 nmol of phosphateÆmin )1 Ælg )1 EmbR protein, the phosphoryl- ated form of EmbR displayed an ATPase activity of 0.257 nmol of phosphateÆmin )1 Ælg )1 EmbR ... ATP hydrolysis is emerging as a central theme in prokaryotic signal transduction systems [25,26]. Therefore, the effect of PknH-mediated phosphory...
Ngày tải lên: 16/03/2014, 14:20