... desensitization of these receptors. GC-A is phos- phorylated on six serine and threonine residues present in the protein kinase-like domain in the basal state [2]. Mutation of any of these sites to alanine ... guanylin/uroguanylin family of peptides. GC-C is predominantly expressed in intestinal cells, where it was initially described as being the mediator of the action of th...
Ngày tải lên: 08/03/2014, 08:20
... features to high- light the distinction that is to be conveyed to the listener (p. 450). Our current work incorporates certain prosod- ic information into the process of parsing, com- bining ... beaters> **// The actual output of the pre-processor is in two parts, one an indexed string of lexical items plus prosodic information, the other a string of tone groups...
Ngày tải lên: 20/02/2014, 21:20
Tài liệu Báo cáo khoa học: "Explaining German Case through Computational Experiments in Fluid Construction Grammar" ppt
... one branch. 2. In parsing, search has to be equal to the se- mantic effort. The single branch constraint in production checks whether the definite articles are suffi- ciently distinct from one another. Since ... illustrated in the top of Figure 1. This Fig- ure shows the search tree of a small grammar when parsing the utterance Die Kinder gaben der Lehrerin die Zeichnung (...
Ngày tải lên: 22/02/2014, 03:20
Tài liệu Báo cáo khoa học: "TOWARDS A CORE VOCABULARY FOR SYSTEM A NATURAL LANGUAGE" potx
... language for B3 trying to stay within at least tile vocabulary of B, , to add lhe words used in the fommlations to the original set, and continue until one cannot think of further rules. I claim ... vary in importance for different speak- ers of a language, it will be difficult if not ina- possible to eliminate arbitrariness. Rather, a definition of representative...
Ngày tải lên: 22/02/2014, 10:20
Báo cáo khoa học: D-strand perturbation and amyloid propensity in beta-2 microglobulin ppt
... posi- tioned to play a protective role against intermolecular cross-b interactions in the native protein. On the other hand, the location of His5 1in the D-strand is intrigu- ing: in native b2m, the His51 ... aggregation [1]. Therefore, introducing a b-bulge in an otherwise linear edge b-strand may impair the amyloid aggrega- tion of proteins hosting b-sheets, improving t...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: "Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval" potx
... chosen. The other terms are added in the similar way. Recall that we use mutual information to select the top 10 accompanying terms of a Chinese query term in ATT model. The 5 ~ row shows that the ... Chinese-English information retrieval on different models, we translate the 50 English queries into Chinese by human. The topic 332 is considered as an example in t...
Ngày tải lên: 17/03/2014, 07:20
Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt
... model the P-selectin-binding domain of the mucin-like glycoprotein PSGL-1 [73,74]. This ligand is involved in the initial homing of leuko- cytes to sites of in ammation [73,74]. The binding of PSGL-1 ... two glycans onto a galactosidase (lacZ) reporter protein. In all cases, the proteins maintained native function as well as being endowed with additional lectin-binding proper...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of cofilin to actin filaments pdf
... Pi on the subtilisin digestion indicates stabilization of the D-loop. Monitoring the binding of cofilin to F-actin by limited proteolysis The effect of Pi on the binding of cofilin to F-actin was ... by closing the ‘main door’ of the nuc- leotide binding cleft. Taken together, cofilin binding transforms the nucleotide binding cleft of F-actin protomers to a more G-actin-lik...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: From heart to mind The urotensin II system and its evolving neurophysiological role ppt
... stri- king similarities to the somatostatin receptor family, most notably in the transmembrane domains. The pharmacological relatedness of somatostatin receptors is demonstrated by the fact that the ... the receptor. However, the binding sites matched the projection areas of the LDT PPT complex leading to the hypothesis that the binding sites might represent presy...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1 doc
... guanine residues at the N2 position in double- stranded DNA [11]. The covalent binding to DNA is apparently responsible for the cytotoxic action [12] and the capacity of the drug to trigger apoptosis ... concentration in the dark at room tempera- ture, during the period specified in the legend, prior to adding 5 lL of a 50% glycerol solution containing tracking dyes...
Ngày tải lên: 20/02/2014, 11:20