Báo cáo khoa học: Phosphorylation of Hrs downstream of the epidermal growth factor receptor docx

Báo cáo khoa học: Phosphorylation of Hrs downstream of the epidermal growth factor receptor docx

Báo cáo khoa học: Phosphorylation of Hrs downstream of the epidermal growth factor receptor docx

... role in the trafficking of growth factor/ receptor complexes through early endosomes. Stimulation of cells with epidermal growth factor (EGF) rapidly leads to phosphorylation of Hrs, raising the question ... Phosphorylation of Hrs downstream of the epidermal growth factor receptor Kristi G. Bache 1 , Camilla Raiborg 1 , Anja Mehlum 1 , Inger Helene Ma...

Ngày tải lên: 17/03/2014, 11:20

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Báo cáo khoa học: Phosphorylation mechanism and structure of serine-arginine protein kinases pot

Báo cáo khoa học: Phosphorylation mechanism and structure of serine-arginine protein kinases pot

... of some precursor mRNAs [34], other studies have shown that the phos- phoryl content of the RS domain is important. For example, phosphorylation of SRSF1 controls the alter- native splicing of ... to the nuclear entry of SR pro- teins. It has been shown that phosphorylation of the RS domain leads to enhanced interactions with the nuclear import receptor, transport...

Ngày tải lên: 15/03/2014, 00:20

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Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt

Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt

... studies devoted to the elucidation of the phosphorylation sites in HSL and the regulation of its translocation, few studies have addressed the effects of PKA phosphorylation on the HSL molecule ... in the presence of the given concentrations of the hydro- phobic probe bis-ANS, using TO as substrate. The activity of phos- phorylated HSL in the TO assay was n...

Ngày tải lên: 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx

Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx

... tube assays. The accumulation of C-YES in the precipitates correlated with the appearance of kinase activity in those samples. The level of depletion of kinase activity mirrored the level of depletion of ... strategies for the treatment of cancer. The activity of the CDK4 ⁄ cyclin D holoenzyme is regulated by multiple mechanisms, the most important of which...

Ngày tải lên: 18/02/2014, 18:20

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Báo cáo khoa học: Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A⁄C pot

Báo cáo khoa học: Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A⁄C pot

... which is the most recently identified member of the JIP group of scaffold proteins [11]. To determine which region of hsMOK2 interacts with JLP, we co-transformed the yeast strain L40 with the library ... either the nonfinger acidic domain (pLex–NH 2 ) or the finger domain (pLex–finger) of hsMOK2, and performed b-galactosidase assays. The JLP 1–141 domain interacted only wit...

Ngày tải lên: 07/03/2014, 01:20

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Báo cáo khoa học: Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily pot

Báo cáo khoa học: Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily pot

... 1B). The partial phosphorylation of Grx4p still observed in the case of the two mutants (corresponding to 30–40% of that of the wild-type) could be explained either by the intervention of another ... elongation. We have then examined the effects of Ser258 phosphorylation of Bud32p on the transcriptional activity of the EKC ⁄ KEOPS com- plex by analyzing th...

Ngày tải lên: 07/03/2014, 04:20

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Báo cáo khoa học: Phosphorylation of NF-jB proteins by cyclic GMP-dependent kinase A noncanonical pathway to NF-jB activation potx

Báo cáo khoa học: Phosphorylation of NF-jB proteins by cyclic GMP-dependent kinase A noncanonical pathway to NF-jB activation potx

... Substrate phosphorylation of p49 or p50 depends on the presence of PKG and is enhanced by the addition of cGMP, whereas cGMP in the absence of the kinase does not mediate measurable incorporation of ... induction of the faster migrating NF-jB band. Note that the resting levels of NF-jBbinding are relatively high in O3 cells, because the clone depends on the pre...

Ngày tải lên: 08/03/2014, 02:20

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Báo cáo khoa học: Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat pdf

Báo cáo khoa học: Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat pdf

... modulate the process of aggregation. Results Phosphorylation of Ser356-induced conforma- tional change in peptide R4 To investigate the effect of phosphorylation at Ser356 on the native structure of ... site. Identification of the hydrogen-bonding partners depends on detailed investigations into the pH depen- dence of their NMR parameters over the pH range 3–8. Obvi...

Ngày tải lên: 16/03/2014, 05:20

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Báo cáo khoa học: Photosynthetic acclimation: Structural reorganisation of light harvesting antenna – role of redox-dependent phosphorylation of major and minor chlorophyll a/b binding proteins pot

Báo cáo khoa học: Photosynthetic acclimation: Structural reorganisation of light harvesting antenna – role of redox-dependent phosphorylation of major and minor chlorophyll a/b binding proteins pot

... structure of the higher plant PSI supercomplex provided an insight into the organization of the PSI core and the assembly of its associated LHCI together with the bound pig- ments and cofactors ... cofac- tors of the components of the photosynthetic electron transport chain). However, the most rapidly changing environmental factor is the quantity and spectral qua...

Ngày tải lên: 16/03/2014, 06:20

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Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx

Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx

... phosphorylation. Effect of RS motif phosphorylation on oligomerization of the N protein To better understand the effect of RS motif phosphor- ylation on the biological function of the N protein, we Fig. 3. The translation ... that of the full-length N protein (data not shown). Taken together, these data suggest that the RS-rich region of the SARS- CoV N protein...

Ngày tải lên: 23/03/2014, 07:20

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