Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx

Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx

Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx

... 15-kDa band, containing both the N- and C-terminal chains that are identical in size (band A). Activation of double-chain trypsinogen to double-chain trypsin results in the appearance of band B, ... digestion of ingested proteins; are unaffected by up-regulation of anionic trypsinogen. In contrast, trypsinogen activation was markedly diminished by an increased ratio...
Ngày tải lên : 17/03/2014, 03:20
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Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf

Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf

... around the binding site: they induce a line broadening of 1–100 Hz in nuclei located within 5 A ˚ of the binding site, depending on the molecular mass of the protein and the strength of the magnetic ... perturbation of the hydrophobic core of the molecule, which is induced by ion binding at the M4 site. Rearrangement of the Glu19 and Asp23 side chains in uences the main c...
Ngày tải lên : 18/02/2014, 16:20
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Báo cáo khoa học: Human skin cell stress response to GSM-900 mobile phone signals In vitro study on isolated primary cells and reconstructed epidermis docx

Báo cáo khoa học: Human skin cell stress response to GSM-900 mobile phone signals In vitro study on isolated primary cells and reconstructed epidermis docx

... expression and induce DNA damage in a fibroblastic cell line and human fibroblast primary cells, respectively [58,59]. In our study, the effects of GSM-900 exposure on human skin cells were investigated ... has been reported in a number of cell types, including skin cells. The major HSPs expressed in the skin [5] are Hsp70 (both cognate and inducible forms) [6] and Hsp27...
Ngày tải lên : 07/03/2014, 11:20
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Báo cáo khoa học: On the aggregation properties of FMRP – a link with the FXTAS syndrome? pot

Báo cáo khoa học: On the aggregation properties of FMRP – a link with the FXTAS syndrome? pot

... which contains also arginine- and glycine-rich (RGG) motifs [4,5]. Co-presence of differ- ent nucleic acid binding domains in FMRP suggests that the protein has a prominent capacity to bind nucleic ... for the N-terminal domain which contains two Tudor domains. KH stands for protein K homology domain. Linker indicates the region between the second Tudor domain and KH1. NES stands for...
Ngày tải lên : 14/03/2014, 23:20
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Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

... ubiquitinated in H1.2, H1.3 and H1.4 in human HeLa cells, but not in MCF7 cells. In mouse tissue, Lys116 of H1.1 and Lys46 of H1.2 and H1.3 in the spleen were the only sites of ubiquitination. ... parameters of the fibre formed by folding the zig-zagging chain of nucleosomes in inactive chromatin, the location of the linker histone in relation to the nucleosom...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: "The grapho-phonological system of written French: Statistical analysis and empirical validation" pdf

Tài liệu Báo cáo khoa học: "The grapho-phonological system of written French: Statistical analysis and empirical validation" pdf

... characteristics of this mapping. The results indicate that human naming performance is influenced by the frequency of graphemic units in the language and by the predictability of their mapping to ... grapheme entropy influence performance on pseudoword naming. We discuss the implications of those findings for current models of phonological coding in visual word re...
Ngày tải lên : 20/02/2014, 19:20
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Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

... the role of PRDM1 inhibition of HGAL and LMO2 in the pathogenesis and outcome of DLBCL. Materials and methods Cell lines and protein accession numbers Human non-Hodgkin lymphoma cell lines VAL ... by interacting with actin and myosin proteins [12,13] as well as by regulating the RhoA signaling pathway [12,14]. HGAL induces activa- tion of RhoA and its downstream effect...
Ngày tải lên : 05/03/2014, 23:20
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Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf

Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf

... the physical interactions between receptor proteins [51,52]. Results Radioligand binding assay As shown in Table 1, the binding parameters obtained for dopamine D 1 receptor and its mutant indicate ... different pro- teins of interest, Pearson’s correlation coefficients and coefficients of determination were estimated (Fig. 2C). In case of cells co-expressing dopamine D 1 and do...
Ngày tải lên : 07/03/2014, 03:20
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Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

... result of loss of induction at the transcriptional level, of loss of activation of the synthetase protein itself, or of derepression of enzyme(s) catalysing PMLA degradation. An interest- ing interplay ... a domain. The domain fold contains a pair of calcium binding sites. While the bc-crystallins of lens (not shown) and lower organisms in Fig. 2 contain two domain fo...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi potx

Báo cáo khoa học: The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi potx

... trans- formant strains were named T3 and T4. The molecular integrity of carD was investigated in T3 and T4 strains, in two nonsectoring transformants, T1 and T2, and in the SF134 original strain. A PCR test ... rate of 1mLÆmin )1 , with a linear gradient from 100% B to 43% B within 45 min, and then to 0% within 1 min, with the final conditions being maintained for another 2...
Ngày tải lên : 14/03/2014, 22:20
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