Báo cáo khoa học: Regulated interaction of endothelin B receptor with caveolin-1 potx

... receptors. J. Biol. Chem. 267, 20551–20554. Ó FEBS 2003 Endothelin-< /b> 1 dissociates the ETBR caveolin-1 complex (Eur. J. Biochem. 270) 1827 Regulated < /b> interaction < /b> of < /b> endothelin < /b> B receptor with caveolin-1 Tomohiro ... might be able to compensate in the case of < /b> b 2 -adren- ergic receptor, but not in the case of < /b> ET B R. Therefore, the m...

Ngày tải lên: 17/03/2014, 03:20

... (A–I) Immunofluorescence double-staining of < /b> one subtype of < /b> annexin with the other subtype of < /b> annexin. A section was treated with rabbit antiserum raised against one subtype of < /b> annex- in (red: A, annexin ... in each of < /b> the observations with rabbit antiserum (Texas Red) or mouse antiserum (fluorescein isothiocyanate), and all of < /b> the images obtained...

Ngày tải lên: 07/03/2014, 05:20

... makes hydrophobic contacts with the a1-helix and the b- sheet. The b5 -strand of < /b> SlyD is split into two halves, namely b5 a and b5 b, separated by a five-residue bulge bearing a close resemblance to the ... This is stabilized by hydrophobic interactions with the a1-helix, the b2 -strand and the b3 -strand, but it also establishes a few contacts with the interconnecting segme...

Ngày tải lên: 30/03/2014, 01:20

... inability of < /b> cholera toxin B subunit to block LT-I binding to the cells. Binding of < /b> LT-I to cells, when GM1 was blocked by the cholera toxin B subunit, was characterized by an increased number of < /b> ... members of < /b> the CT fam- ily [1,2]. LT-I and CT are AB 5 toxins, in which the pentameric B subunit [B subunit of < /b> E. coli heat labile toxin (LT -B) , B su...

Ngày tải lên: 30/03/2014, 10:20

... stage. Reduction of < /b> Ab synthesis with inhibitors of < /b> b- and c-secretase was pursued long before the molecular identities of < /b> the drug targets were known or APP transgenic mice were available. With robust and ... altered metabolism of < /b> Ab,in particular aggregation-prone Ab species like Ab42, initiates AD pathogenesis. Oligomeric assemblies of < /b> Ab trigger agg...

Ngày tải lên: 16/02/2014, 09:20

... the binding of < /b> MP8 occurred through interactions of < /b> its carboxylate substituents with amino acids of < /b> the antibody, and that the protein provided a partial steric hindrance of < /b> the distal face of < /b> ... hydrophobicity, antibody 3A3 was confirmed to bring about a partial steric hindrance on the distal face of < /b> MP8. Subsequently, the influence of < /b> the...

Ngày tải lên: 19/02/2014, 12:20

... the binding to beads bearing GST–LBR fr agments was examined a s above. Ó FEBS 2002 Regulation of < /b> the binding of < /b> LBR to chromatin (Eur. J. Biochem. 269) 947 binding of < /b> the N -terminal portion of < /b> ... ercentage of < /b> beadswithboundchromatinwasdetermined.Ineachfigure,thetime of < /b> preincu bation o f beads with a cytosol fraction (A), the chromatin concentrat...

Ngày tải lên: 22/02/2014, 04:20

... B Cys29Ser mutant did not label with the probe, thereby excluding nonspecific binding of < /b> the probe to the enzyme (Fig. 3, lanes 7–9). This is in agreement with specific labelling of < /b> cathepsin B ... 9 21 kDa Coomassie staining Autoradiography Fig. 3. Labelling of < /b> procathepsin B by 125 I-DCG-O4. Five micro- grams of < /b> recombinant protein (pCatB, procathepsin B...

Ngày tải lên: 07/03/2014, 03:20

... Samples were prepared by mixing a selected amount of < /b> DAG lactones with 30 lL of < /b> the vesicles containing the fluores- cent probe, and 30 lLof50mm Tris-base buffer (pH 8.2), followed by addition of < /b> distilled ... 92–114. 25 Lasch J (1995) Interaction < /b> of < /b> detergents with lipid vesi- cles. Biochim Biophys Acta 1241, 269–292. 26 Lewin NE & Blumberg PM (2003)...

Ngày tải lên: 15/03/2014, 09:20

... analysis. J. Bioenerg. Biomembr. 26, 49–66. 10. Ubbink, M., Ejdeback , M., Karlsson, B. G. & Bendall, D.S. (1998) The structure of < /b> the complex of < /b> plastocyanin and cytochrome f, determined by paramagnetic ... homogenization buffer without ascorbate plus 20% (v/v) glycerol, and frozen. PSI particles f rom Neph rolepsis were obtained by b- dodecyl maltoside (b- DM) solubiliza...

Ngày tải lên: 16/03/2014, 16:20