Báo cáo khoa học: "Search in the Lost Sense of “Query”: Ques

Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc

... 20–564), and the model is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study are shown in Fig. 3. To elucidate the mechanism of the substrate ... of 3.2) [45] was a solution in the Dali result. It is likely that the inte rface between N-terminal and b-he lical domains participate in binding of...

Ngày tải lên : 19/02/2014, 16:20

8
551
0

Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulﬁde isomerase by disulﬁde bond formation with free cysteines in the substrate-binding domain pptx

... structures, the rest of bacitracin A as ‘Bacitracin A’, and all other amino acids not involved in the crosslink by the single-letter code. The PDI peptide side of the disulﬁde bond is named R1, and the ... of bacitracin on PDI that involves covalent binding of an open thiol form of bacitracin to free cysteines in the substrate-binding domain of PDI. However...

Ngày tải lên : 14/03/2014, 23:20

10
626
0

Báo cáo khoa học: Intrabodies against the EVH1 domain of Wiskott–Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells potx

... in the following combinations: 18SV H –linker and linker) 18V L , 18V H –linker and linker)18V L , 21SV H –linker and linker)21V L , 21V H –linker and linker)21V L and single- chain antibodies, ... overexpressing the EVH1 domain. These results indicate that the EVH1 intrabodies inhibit only the EVH1 domain function that regu- lates IL-2 synthesis signaling without affectin...

Ngày tải lên : 16/03/2014, 14:20

14
493
0

Báo cáo khóa học: Acharan sulfate, the new glycosaminoglycan fromAchatina fulica Bowdich 1822 Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix docx

... be located in the body of this species using alcian blue staining and it was suggested to be the main constituent of the mucus. In the present work, we provide further information on the structure and ... of them. The ﬁnding of Achatina fulica in the area may be related to its commercialization as a food item [15]. The giant African snail is considered a ma...

Ngày tải lên : 16/03/2014, 16:20

10
495
0

Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc

... to the recall curves (Figures 3 and 4), we find: (i) Examination of 50% of the data in the SLs leads to identification of between 75% (AdjN) and 80% (PNV) of the TPs. (ii) For the first 40% of the ... mixed; (ii) the grammatical status of the individual word combinations in the base set, i.e., whether they are part of or constitute a phrase or simply co- o...

Ngày tải lên : 20/02/2014, 18:20

8
516
0

Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using ﬂuorescence spectroscopy pptx

... is the ÔcoreÕ of the CaM-binding site of the enzyme [9,16–21]. The mechanism of AC activation by CaM, and in particular the role of the conformational change resulting from CaM binding, remains ... coupling Fig. 5. Binding of Ant-dATP to AC (d) and AC–CaM (m). The degree of binding of the ligand was calculated from the value of the ampli- tude of t...

Ngày tải lên : 07/03/2014, 15:20

13
409
0

Báo cáo khoa học: "A Chain-starting Classiﬁer of Deﬁnite NPs in Spanish" docx

... are around the eighties, and around the seventies in the case of Vieira and Poesio (2000), who use the Penn Treebank. Luo et al. (2004) make use of both a linking and a starting probability in their ... chain starting. 5. If m is a simple deﬁnite, (a) and the head of m appears in the list of storage units, classify as chain starting. (b) and the head of...

Ngày tải lên : 08/03/2014, 21:20

8
322
0

Báo cáo khoa học: Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control potx

... to examine how the second kinase in the cascade determines the time dependence of the activity of the third kinase, we varied the V max of the second kinase reaction and recalculated the concentration ... strength; the dur- ation of the signal; the ﬁnal signal strength and the integral signal strength. The summing is over all the processes in the...

Ngày tải lên : 16/03/2014, 18:20

15
434
0

Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt

... the sequences of 1CEV and 1RLA and pasted into the structural alignment. The alignment was then corrected by hand. Since the sequences of the two arginases and agmatinase greately differ in the ... agmatinase with the GﬁAandCﬁT substi- tutions in the coding and noncoding strands, respectively, and using the 5¢ and 3¢ primers mentioned above, the full le...

Ngày tải lên : 21/02/2014, 01:21

5
475
0

Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

... repre- sent the last subunits incorporated into the bc 1 complex. On the other hand, the absence of Qcr9p in the DQCR9 ⁄ DQCR10 strain prevented the binding of ISP (Fig. 4B). Interestingly, in the ... addition of ISP and Qcr10p). On the other hand, in the transition from the 500 kDa band to the 670 kDa band, a structural rearrangement of the bc 1 comp...

Ngày tải lên : 18/02/2014, 08:20

15
639
0

Báo cáo khoa học: "Search in the Lost Sense of “Query”: Question Formulation in Web Search Queries and its Temporal Change" pptx

Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc

Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulﬁde isomerase by disulﬁde bond formation with free cysteines in the substrate-binding domain pptx