Báo cáo khoa học: Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells doc

... successful metabolic engineering of freezing tolerance in plants should include such an analysis of the dynamics of metabolism to gain com- prehensive information about the effects of individual overexpression ... simulta- nous reduction in hexose concentration, particularly during the initial period of cold exposure. Using RNA interference-mediated inhibition of the d...

Ngày tải lên: 14/02/2014, 22:20

... argues against a role for a3inthe formation of native MII binding sites, but may reflect the scarcity of these sites in the investigated brain tissues and/or the formation of low affinity binding sites ... microdomains within the same binding site [35]. The proline residue in position 6, which is conserved in all other a-conotoxins, appears to be the major determinant o...

Ngày tải lên: 19/02/2014, 12:20

... can therefore postulate that, when the segment beyond W140 was removed, the secondary structure of the protein disintegrated. Using the peak at 222 nm of the wild-type protein as an index of helical ... located near the flexible C-terminus of SNase. Changes in the fluorescence intensity of W140 reflect a change in the hydrophobic environment surrounding W140 and t...

Ngày tải lên: 20/02/2014, 01:20

... requiring cofactors, multidomain proteins, fusion proteins. In the following we summarize recent progress in this field, whereas the use of IBs in the study of amyloid aggregation is developed in the ... con- formation. In this way, Curtis-Fiske et al. were able to identify native a-helices of the N-terminal 185 residues of the functional domain of the HA2 sub...

Ngày tải lên: 06/03/2014, 00:20

... assay with HT22 cells, to further examine the binding of Nrl to the Ppp2r5c promoter in vivo. Nrl binding to the Ppp2r5c and rhodopsin promoters was examined by quantitative real-time of ChIP samples with ... during photoreceptor development when compared with the patterns of binding of Nrl to the rhodopsin promoter (Fig. 4C,D). The mRNA tran- script levels of Ppp2r5c...

Ngày tải lên: 06/03/2014, 02:20

... with the homologue of the largest subunit of chromatin assembly factor 1 (CAF-1) in the basidiomycete Coprinopsis cinerea (Coprinus cinereus). Using C. cinerea LIM15/DMC1 (CcLIM15) as the bait in ... responsible for binding to CcLim15. The N-ter- minus (CcCac1L-N; amino acids 1–381) contained the KER domain, whereas the C-terminus (CcCac1L- C; amino acids 382–812) contai...

Ngày tải lên: 07/03/2014, 05:20

... near the flexible C terminus of SNase. Changes in the fluorescence intensity of W140 reflect a change in the surrounding hydrophobic environment of the tryptophan and thus indicate a change in the overall ... exists in these mutants (Fig. 1). Thermal analysis of protein unfolding Thermal denaturation determined by DSC was used to measure the stability of the mut...

Ngày tải lên: 07/03/2014, 21:20

... likely. The separation of the lemma and suffix helps in tiding over the data sparsity problem by allowing the system to reason about the suffix-case marker com- bination rather than the combination of ... described in table 1 was used for the experiments. The SRILM toolkit 2 was used to create Hindi language models using the target side of the train- ing corpus. Tr...

Ngày tải lên: 08/03/2014, 00:20

Ngày tải lên: 08/03/2014, 01:20

... summarize the outcomes of our statistical model on various size of the training data, x-coordinate denotes the size of the training set, where "1" indicates that the training set is ... 9.1 points yesterday morning" Figure 3: the transformed form of the path with dash line for the second pass processing 2.4 The statistical parameter training In this...

Ngày tải lên: 08/03/2014, 05:20