Báo cáo khoa học: "Comprehensibility of Machine-aided Translations of Russian Scientific Documents" potx
... engineering 6.5 27.0 TRANSLATIONS OF RUSSIAN DOCUMENTS 7 ADDITIONAL ANALYSES Preliminary analyses of the linguistic characteristics of the machine translations and of the extent of input/ output ... Linguistics, vol.10, nos.1 and 2, March and June 1967] Comprehensibility of Machine-aided Translations of Russian Scientific Documents* by David B. Orr and...
Ngày tải lên: 16/03/2014, 19:20
... determined by the rate of association. It should be noted that quanti- tative analysis of the more rapid phase of association requires measurement of the binding on time scales of minutes, a time ... presence of unlabeled PCSK9 (Fig. 4A). In the presence of a high concentration of unlabeled wild-type PCSK9, the half- time of the rapid phase was reduced from 19 to 16 min and...
Ngày tải lên: 14/02/2014, 14:20
... analysis of purified PhyH, PhyH-DI and PhyH-DII. Lane M, molecular weight markers; lane 1, culture supernatant of PhyH; lane 2, culture supernatant of PhyH-DII; lane 3, culture supernatant of PhyH-DI; ... Environmental factors that affect the catalytic activities of PhyH and PhyH-DII. (A) Effect of 0–5.0 mM Ca 2+ at 37 °C. (B) Effect of pH at 37 °C. (C) Effect of temperature at...
Ngày tải lên: 14/02/2014, 15:20
Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt
... University of Bath, UK 2 Department of Biochemistry, University of Wisconsin–Madison, USA 3 Department of Chemistry, University of Wisconsin–Madison, USA Introduction Upon catalyzing the cleavage of ... regarding a new class of surrogates for the phosphoryl group. Results and Discussion Sulfonimides as inhibitors of RNase A We began by determining the ability of three backbo...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc
... transfer of phosphate esterified in the 5¢ position of 6-hydroxypu- rine monophosphate nucleosides [1]. The transfer of phosphate can lead to phosphorylation of inosine, guanosine and a number of their ... disappearance of the heavier inactive peak. Furthermore, FPLC analysis of the recombinant wild-type cN-II showed the presence of the tetrameric active form irrespective of...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... K m ) of PRTFDC1 towards hypoxanthine and guanine was only 0.26% and 0.09%, respectively, of that of HPRT. This low activity could be explained by the fact that PRTFDC1 has a Gly in the position of the ... metabolic consequences of having HPRT deficiency are an overproduction of uric acid and elevated levels of PRPP [3]. Patients hav- ing mutations resulting in partial HPRT defici...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt
... previously demonstrated the application of this method to the determination of the glycan structure of a form of AFP [10]. However, identification of the details of a glycan structural change on a ... methylesteri- fication of sialic acid moieties. All spectra were obtained in the positive ion mode using MALDI– quadrupole ion trap (QIT)-TOF MS. A strategy for discovery of cancer...
Ngày tải lên: 16/02/2014, 08:20
Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... The expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and ... kidney, gill, gut, liver and skin tissue of healthy fish (data not shown). After stimulation of kidney cells with a variety of immunostimulants, the expression of t-bet, stat6 and fo...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx
... Kessler Department of Clinical Medicine, University of Oxford, UK Introduction The genus Yersinia consists of three pathogenic species that are agents of a variety of diseases, one of which was historically ... GTPase-binding capacity of YpkA and OTUB1-mediated increase in susceptibility to infection (Fig. 6). The binding of small GTPases has been reported to be independent o...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... already containing two copies of each of the bc 1 subunits plus the monomeric form of Bcs1p) and (b) the 500 kDa bc 1 sub-complex contains a single copy of each of the bc 1 subunits which, in ... oligomeric forms of bc 1 assembly factors [12,29,32,41]. Of course, the possibility that other protein components of the respi- ratory chain, such as subunits of the cytochrome c ox...
Ngày tải lên: 18/02/2014, 08:20