Báo cáo khoa học: R120G aB-crystallin promotes the unfolding of reduced a-lactalbumin and is inherently unstable ppt

... miR-23a potently promotes the growth of the gastric adeno- carcinoma cell line MGC803, providing the first proof- of- concept that there is a potential link between the tumor promoter miR-23a and gastric ... Institute and Hospital and the National Foundation of Cancer Research. All of the tumor types were confirmed by pathologic analysis. The experiments were unde...

Ngày tải lên: 18/02/2014, 04:20

... irrespective of the presence of the supernatant from the initial centrifugation, the yield of EJ products did not appreciably change (com- pare lanes 1 and 2). The replacement of the superna- tant ... DNA in the absence of Ku and predominantly forms a large com- plex without any mobility shift in the well of the gel [31]. The stability of the complex ag...

Ngày tải lên: 19/02/2014, 06:20

... University of Jerusalem, Israel 2 Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, USA Actin dynamics, the polymerization and depolymeriza- tion of ... actin protomers located in the vicinity of the barbed end of the filament, pro- ducing an ATP or ADP–Pi cap at this end. Because of the presence of this ca...

Ngày tải lên: 19/02/2014, 07:20

... completing the catabolism of the pyrrolidine moiety of nicotine. Expression of the genes of these enzymes was dependent on the presence of nicotine in the growth medium. Thus, two enzymes of the nicotine ... in this study and RT-PCR analysis of transcripts. (A) Schematic representation of the pAO1 gene and ORF cluster flanked by Tn554 and DTn. The cluster...

Ngày tải lên: 19/02/2014, 07:20

... caused the loss of the other two subunits. This is consistent with the crystal structure of the cytochrome bc 1 complex that shows that these three subunits comprise its core, around which the remaining subunits ... on the left side of the blots. The Western blots are shown in panels A and B and the relative amounts of each of the subunits determined by den...

Ngày tải lên: 19/02/2014, 12:20

... fully support these previous findings and on the other hand extend them by far and set them in a more general context, as both a-subunits of P4h, PDI as the b-subunit of P4h [13] and the collagen ... [29] and also for the key players of angiogenesis [30]. Considering the parallel up-regulation of enzymes involved in collagen fiber formation raises the question of w...

Ngày tải lên: 20/02/2014, 02:21

... loaded with the 35 S immunoprecipitates and the arrowheads indicate the position of Ga q and Ga 16 . The molecular mass standards are indicated. The arrow indicates the position of some unspecific bands. Proteasome ... or maturation of the protein. An increase was also observed in the rate of degradation of the remaining mutant protein (20% left of the prote...

Ngày tải lên: 20/02/2014, 03:20

... overload conditions, and is also implicated in intracellular Fe metabolism [3,9,10]. An important aspect of this work was the assessment of the effect of novel Fe chelators on the uptake and fate of NTBI and ... to the obligatory treatment of the anemia with blood transfusions. The contribution of plasma NTBI to the toxicity associated with Fe overload in the...

Ngày tải lên: 20/02/2014, 11:20

... tested the level of mRNA for subunit VIIa, which is expressed as isolog H and L. The L isolog is ubiquitously expressed in all the tissues whereas the H isolog is detected in the heart and skeletal ... switch and alters the expression of the two nuclear genome coded isoforms of CytOX V [10,32]. The regulation of genes CytOX5a and CytOX5b, coding for the...

Ngày tải lên: 20/02/2014, 23:20

... corpus is indicative of their terminological sta- tus, and has not addressed the issue of discovering terms when data is sparse. This becomes apparent in the case of noun compounding, which is extremely productive: ... the BNC more than once (CoocF > 1) the heuristic's accu- racy is increased by 11.0%. However, the number of potential compounds is reduce...

Ngày tải lên: 22/02/2014, 02:20