Báo cáo khoa học: Peroxisome proliferator-activated receptor a plays a vital role in inducing a detoxiﬁcation system against plant compounds with crosstalk with other xenobiotic nuclear receptors docx

... 5¢-TCAAGAATGGATACACATAAACACAAGGA-3¢ for Cyp2c29; 5¢-CCAGCTCTGCTTCATTCCTCTCT-3¢ and 5¢-CGCAGGAATGGATAAACATAAGCA-3¢ for Cyp2c38; 5¢-ACTTCTCTGTGGCAAGCCCTGTTG-3¢ and 5¢-TCCACTAGCACAGATCACAGATCATGG-3¢ ... Peroxisome proliferator-activated receptor a plays a vital role in inducing a detoxiﬁcation system against plant compounds with crosstalk with other xenobiotic nuclear receptors Kiyoto ... 5¢-TGCAGAACTTCCACTTCAAATCCA-3¢ and 5¢-AATTTCCCCCTTCTCTGGCTACC-3¢for Cyp 2a5 ; 5¢-TTGTTCTAAAAGTTGTGCCACGGGATG-3¢ and 5¢-AGAGATGATCCCATGAGAAACGGTGAA-3¢ for Cyp 3a4 4; 5¢-AGATCATCATTCCTTGGCACTGG-3¢ and...

Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... the participatingTable 1. Amino acid frequencies (%) in a- amylase linkers, in a setof globular proteins, in the Swiss-Prot databank and in intrinsicallyunstructured proteins.Aminoacid Linkers a GlobularproteinsbSwiss-ProtcIntrinsicallyunstructuredproteinsbAla ... sequence and genomedatabanks. Interestingly, this domain was found in some closely related bacterial species, but mainly in nonvertebrate animals, and invariably connected via a linker to an animal-type ... function in activity, substrate bindingand structural dynamics.Materials and methodsExperimental dataThe presence of a C-terminal putative binding domain in various animal cell extracts was checked...

Tài liệu Báo cáo khoa học: Liver X receptor agonists inhibit tissue factor expression in macrophages docx

... of cardiovascularremodeling. Nat Med 8, 856–863.49 Aizawa K, Suzuki T, Kada N, Ishihara A, Kawai-Kowase K, Matsumura T, Sasaki K, Munemasa Y,Manabe I, Kurabayashi M, Collins T & Nagai ... Shindo T, Manabe I, Fukushima Y, Tobe K, AizawaK, Miyamoto S, Kawai-Kowase K, Moriyama N, ImaiY, Kawakami H, Nishimatsu H, Ishikawa T, Suzuki T,Morita H, Maemura K, Sata M, Hirata Y, KomukaiM, ... adipocytes. Proc Natl Acad SciUSA 98, 507–512.22 Terasaka N, Hiroshima A, Koieyama T, Ubukata N,Morikawa Y, Nakai D & Inaba T (2003) T-0901317, a synthetic liver X receptor ligand, inhibits developmentof...

Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

... 5¢-CACGTACAAAGAGAACGTCGACGACG-3¢5¢-CGTCGTCGACGTTCTCTTTGTACGTG-3¢R11 4A 5¢-GAGAATTTCGAGCACGATACAGACTCCC-3¢5¢-GGGAGTCTGTATCGTGCTCGAAATTCTC-3¢Y116D 5¢-CGACGACGAGACAGACTCCCAGAACATGTC-3¢5¢-GACATGTTCTGGGAGTCTGTCTCGTCGTCG-3¢Y. ... Chaperones 8, 381–394.70 Rajaraman K, Raman B, Ramakrishna T & Rao CM(2001) Interaction of human recombinant aA- andaB-crystallins with early and late unfolding intermedi-ates of citrate ... Theexpanding family of Arabidopsis thaliana small heatstress proteins and a new family of proteins containing a- crystallin domains (Acd proteins). Cell Stress Chaper-ones 6, 225–237.9 Narberhaus...

Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx

... by calcium-activa-ted transglutaminase eliminates chaperone activity,suggesting a role in reduced lens transparency andcataract [56]. Oxidation and transglutaminase inducedcross-linking may ... properties, and reduced chaperoning links trun-cation to cataract. a- crystallin deamidation involvesthe nonenzymatic conversion of asparagine to eitheraspartate or isoaspartate, and glutamine becomesglutamic ... cataract and a- crystallin post-trans-lational changes is compelling, but there are examplesof extensive a- crystallin modiﬁcation before diseaseappears, and cataract associated protein changes...

Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx

... Molecular Analyst apparatus (Biorad).Respiratory parameters and respiratory ratio in intact cellsRespiratory parameters and the coupling state were inves-tigated in intact cells by polarography using ... 5¢-TAACCCCACCCTACTAAACC-3¢ and 5¢-GATTATGGGCGTTGATTAGTAG-3¢; b-globin: 5¢-CAACTTCATCCACGTTCACC-3¢ and 5¢-ACACAACTGTGTTCACTAGC-3¢.Western blotCells were rinsed in NaCl ⁄ Pi, trypsinized and collected in centrifuge ... 5¢-GTGTTTCAGGGCTTCTCTGC-3¢; Cyt c:5¢-CCAGTGCCACACCGTTGAA-3¢and 5¢-TCCCCAGATGATGCCTTTGTT-3¢; ATP synthasesubunit b:5¢-CCTTCTGCTGTGGGCTATCA-3¢ and 5¢-TCAAGTCATCAGCAGGCACA-3¢; ND5: 5¢-TAACCCCACCCTACTAAACC-3¢...

Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"

... routinely obtained on a daily basis, at least in TheNetherlands [13].There may be advantages to eliminating daily routine CXRs.First, a routine strategy carries the risk that abnormalities thateither ... 'old' or 'new' finding). In case an abnormalitywas worsening, and fulfilling the criteria as in table 1, it wascategorized as 'new'. All CXRs were reviewed by the team at10:00 ... by the attending physician; a 'new unex-pected finding' was any new finding not predicted by theattending physician; and an 'old unexpected finding' was anyold finding not...

Tài liệu Báo cáo khoa học: The alr2505 (osiS) gene from Anabaena sp. strain PCC7120 encodes a cysteine desulfurase induced by oxidative stress docx

... Latiﬁ A, Ruiz M, Jeanjean R & Zhang CC (2007)PrxQ -A, a member of the peroxiredoxin Q family, plays a major role in defense against oxidative stress in thecyanobacterium Anabaena sp. strain ... mechanisms involving sulfurtransfer in Anabaena, as well as other cyanobacteria in general because little is known so far about thesemechanisms.Experimental proceduresBacterial strains, plasmids and ... AAC TTC GCReverse: GCC TTG GTG ACA ATT ATG TAalr2505 Forward: GTT GCA ACA CAC CAA TTT CGReverse: CAA GCA CGG GAA ATT TTA GCOsiS: oxidative stress-induced cysteine desulfurase M. Ruiz et al.3722...

Tài liệu Báo cáo khoa học: Properties of ecdysteroid receptors from diverse insect species in a heterologous cell culture system – a basis for screening novel insecticidal candidates docx

... S1. Amino acid alignment of linker region andligand-binding domain (LBD) of ecdysone receptors. Fig. S2. Amino acid alignment of linker region andligand-binding domain (LBD) of ultraspiracle ... Ogura T, Minakuchi C, Nakagawa Y, Smagghe G &Miyagawa H (2005) Molecular cloning, expression anal-ysis and functional conﬁrmation of ecdysone receptor and ultraspiracle from the Colorado ... cell culture system – a basisfor screening novel insecticidal candidatesJoshua M. Beatty1, Guy Smagghe2, Takehiko Ogura3, Yoshiaki Nakagawa3, MargaretheSpindler-Barth4and Vincent C....

Tài liệu Báo cáo khoa học: Modeling of tRNA-assisted mechanism of Arg activation based on a structure of Arg-tRNA synthetase, tRNA, and an ATP analog (ANP) ppt

... thatN-terminaldomainAnticodon-binding domain'Stem contact fold' domainCatalytic domainInserted domain 1Connective polypeptide domainRossmann fold domain A BN-terminaldomainAnticodon-binding ... JapanIntroductionMost aminoacyl-tRNA synthetases (aaRSs) catalyze theformation of aminoacyl-AMP in the presence ofMg2+[amino acid + ATP ﬁ aminoacyl-AMP +pyrophosphate (PPi)] and the reverse reaction (amino-acyl-AMP ... molecularmechanism for the Arg-tRNA synthetase-catalyzed deacylation of Arg-tRNA (Arg-tRNA + AMP ﬁ Arg-AMP + tRNA at high pH), in whichthe deacylation of aminoacyl-tRNA bound on Arg-tRNA synthetase...

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