Báo cáo khoa học: High and complementary expression patterns

Báo cáo khoa học: Human telomeric G-quadruplex: structures of DNA and RNA sequences ppt

... formed between the 3¢-end of each block; and (c) 5¢-to-3¢, in which the stacking interface is formed between the 5¢-end of one block and the 3¢-end of the other. In the ‘same-direction stacking’ ... the ends of the G-tetrad core, (b) groove binding, (c) taking place of one or more strands in the core, (d) interacting with the backbone (core and loops)...

Ngày tải lên : 06/03/2014, 09:22

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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

... proteins they probably form part of the copper binding sites in this protein. Although there are four histidines in the C-terminal, another histidine is present at position 18, and given the folded ... with glycine alone was performed and no binding was observed. In our hands, as others [54], the most reproducible data was obtained from injections of the metal into a s...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Molecular cloning, recombinant expression and IgE-binding epitope of x-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis ppt

... recombinant x-5 gliadin protein that can be used for diagnosis and possibly treatment of WDEIA. Results Identiﬁcation of IgE-binding epitopes in x-5 gliadin The IgE-binding epitopes of x-5 gliadin ... in x-5a gene in Fig. 2, includes all of the detected IgE-binding epitope sequences. After ampliﬁcation of the DNA encoding this half of the x-5a gliadin protein by...

Ngày tải lên : 20/02/2014, 01:20

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Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

... targets of PRDM1 repression. These include genes required for maintaining the B-cell phenotype and in maintaining cellular proliferation, for example, CIITA, PAX5, Spi-B, Id3 and c-myc [42–46]. In ... site of PRDM1 binding. The data are presented as percent input and the error bars represent the SEM of three independent experiments. P-values are indicated. Express...

Ngày tải lên : 05/03/2014, 23:20

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Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf

... heparin as a co-factor for inhibition of some of its targets such as thrombin [28]. The co-factor effect of heparin is due to a change in the conformation of the SERPIN as well as the ability of ... heparin and N-acetyl heparin promote an increase in FSAP activity rather than inhibiting it. Thus, polyanion binding to SERPINs, over and above their binding to FSAP, p...

Ngày tải lên : 07/03/2014, 02:20

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Báo cáo khoa học: High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli pot

... peaks. Of these, the loops at peak positions 94, 116, 132, 202 and 215 form the lips of the mouth of the active center pocket (Fig. 1) and are therefore important for catalysis. The other peaks ... mutants and determined their catalytic activity using TNB as the nucleophile. TNB seems to be most appropriate for guiding enzyme engineering intended for the synthe...

Ngày tải lên : 07/03/2014, 05:20

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Báo cáo khoa học: Stage speciﬁc expression of poly(malic acid)-afﬁliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

... bc-crystallin fold. The residues shown in grey indicate the side chains and backbone sites that are involved in calcium binding [24]. The residues in the conserved tyrosine corners are in bold [24]. ... domain folds, spherulin 3a and NKA48 contain only a single domain fold. The stability of these two proteins is highly dependent on calcium binding [25]. The typical...

Ngày tải lên : 07/03/2014, 12:20

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Tài liệu Báo cáo khoa học: Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by ﬂuorescence resonance energy transfer–ﬂuorescence lifetime imaging microscopy in living cells doc

... upon the distance between and relative ori- entation of two ﬂuorophores, being independent of the strength of protein–protein interactions. In the case of very weak interactions as described in ... that induction of FRET does not sim- ply depend on the length of linkers. In the linker con- taining seven amino acids, a Pro-Pro sequence that is not contained in o...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc

... steric interference in the DNA-cleaving catalytic domain of DRc DNAzyme. Reducing the RS to 6 bp increased the rate of DNA cleavage, which approached the self-cleaving rate of DRc DNAzyme in the ... structure and evolution of the DNAzymes. The regulating effects of RS and RNase on the DNA cleavage of DRc DNAzyme After characterizing the DNA-cleaving and...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc

... located in independent domains (a b-domain for the N-terminal cluster and an a-domain for the C-terminal cluster). In the absence of metals, apo-thionein (apo-T) is predominantly unstruc- tured and ... as a result of the formation of disulﬁde bridges [2]. Sec- ond, in contrast to the high thermodynamic stability, the binding is kinetically labile, allowing ra...

Ngày tải lên : 16/02/2014, 15:20

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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Báo cáo khoa học: Human telomeric G-quadruplex: structures of DNA and RNA sequences ppt

Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx