Báo cáo khoa học: Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand pptx

... Casado S, Alonso M, Herrado ´ n B, Tarazona J & Navas J (2006) Activation of the aryl hydrocarbon receptor by carbaryl: computacional evidence of the ability of carba- ryl to assume a planar ... bioassay expres- sing both aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator. By contrast, carbaryl acted as a competitive inhibitor, rat...

Ngày tải lên: 16/03/2014, 10:20

... to WT and CYPD KO mitochondria, and cal- culated on the basis of steady-state titration data by catr and olgm. The activities of ANT and F 0 F 1 -ATP synthase were calculated taking into account ... mediated by the ANT caused by alterations in matrix ATP and ADP levels as a result of changes in F 0 F 1 -ATP synthase activity by kinetic modeling The rate equation of electroge...

Ngày tải lên: 14/02/2014, 19:20

... 234717 E-mail: a. nicolaou@bradford.ac.uk *Present address Faculty of Health and Biological Sciences, School of Pharmacy, University of Notting- ham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor ... tetrahydrofolate – participate in the active methionine and folate pathways. Impaired methionine synthase activity has been implicated in the pathogenesis of anaemias, cancer and...

Ngày tải lên: 19/02/2014, 05:20

... substantia nigra is a neuropathological hallmark of Parkinson’s disease. This leads to a decreased level of dopamine in the striatum. As a result, synaptic transmission is nega- tively affected ... Journal compilation ª 2011 FEBS Modulation of a- synuclein aggregation by dopamine in the presence of MPTP and its metabolite Prashant N. Jethva, Jay R. Kardani and Ipsita Roy De...

Ngày tải lên: 14/02/2014, 19:20

... in membranes but also the amount of sterols derived from SE that are Table 1. Sterol analysis of cells lacking STE20 and CLA4. Data are mean values with standard deviation from at least two independent experiments. lg ... indicated strains were grown to stationary phase and then lipids were extracted and separated by TLC. The amount of SE of the wildtype strain was set at 100%. Data...

Ngày tải lên: 18/02/2014, 13:20

... (5¢-ACTTTTGTCTA CATGTGTGGAGTGAAAGGAATGG-3¢), FNRC26 6A (5¢-ACTTTTGTCTACATGGCTGGACTGAAAGGAAT GG-3¢), FNRC266AL26 8A (5¢-ACTTTTGTCTACATGGC TGGAGCGAAAGGAATGG-3¢) or FNRG267V (5¢-ACTT TTGTCTACATGTGTGTACTGAAAGGAATGG-3¢) and FNRlw ... (5¢-GACAACACTTTTGTCTACATGATGG GACTGAAAGG-3¢) and FNRlw1 (5¢-GTAATCTATCTA CAGAATACAGGAGGGTGATA-3¢) as primers and plas- mid pCV105 [63] as template. In addition, oli...

Ngày tải lên: 18/02/2014, 17:20

... Gonza ´ lez Cappa SM, Katzin AM, An ˜ asco N & Lajma- novich S (1981) Comparative studies on infectivity and surface carbohydrates of several strains of Trypanosoma cruzi. Medicina (B Aires) ... forward and reverse primers pNeo 1 (5¢- CCGGAATTCTGAATGAACTGCAGGACGAGGCAG-3¢) and pNeo 2 (5¢-CCGGAATTCCGGCCATTTTCCACCAT GATATTC-3¢), respectively. The labelled probe specific for rRNA 24Sa was...

Ngày tải lên: 19/02/2014, 07:20

... was also measured [30]. Western blot analysis showed that EPA and DHA increased the amount of intracellular caveolin-3, whereas AA had no effect. A s caveolin-1 and caveolin-3 may f unction as negative ... Terano, T., Tanaka, T., Tamura, Y., Kitagawa, M., Higashi, H., Saito, Y. & Hirai, A. (1999) Eicosapentaenoic acid and docosa- hexaenoic acid inhib it vascular smoo th muscle c ell...

Ngày tải lên: 19/02/2014, 16:20

... two autonomous activation domains (AD1 and AD2) in the C-terminal region. AD1 activity appears to be mediated by CBP ⁄ p300, whereas AD2 activity is apparently mediated through co-activator-associated ... hormone and retinoid receptors; AD, activation domain; AF, activation function; AR, androgen receptor; CARM1, co-activator-associated arginine methyltransferase 1; CoCoA, coiled-coil co-a...

Ngày tải lên: 07/03/2014, 12:20

... region is usually completely masked by aromatic groups. CD spectra were recorded on a Jasco J-715 spectropolarimeter andanalyzedusingtheprogram CDSCAN . For each wavelength scan, the average was taken ... Modulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitro Leila Khatai 1 , Walter Goessler 2 , Helena Lorencova 2 and Klau...

Ngày tải lên: 07/03/2014, 15:20