Báo cáo khoa học: Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric and molecular modeling studies pot

... quadruplex berberine interaction FEBS Journal 275 (2008) 397 1–3 983 ª 2008 The Authors Journal compilation ª 2008 FEBS 3983 Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric ... formation of intramolecular G-quadruplexes by the telomeric G-rich strand inhibits the activity of telomerase [10]. Therefore, ligand- induced stabilizat...

Ngày tải lên: 16/03/2014, 06:20

... affinity of Pabc for cGMP. Binding of cGMP to Pabc is not involved PDE activation Binding of [ 3 H]cGMP to Pabc implies that cGMP binding may be involved in the activation of P abcc to Pabc and ⁄ ... inhibitor and transducin. Kinet- ics and affinity studies. Biochemistry 32, 863 6–8 645. 48 Yamazaki A, Yamazaki M, Bondarenko VA & Matsumoto H (1996) Discriminatio...

Ngày tải lên: 06/03/2014, 00:21

... and to lipoteichoic acid from G ram- positive bacteria. Binding of hemolin to smooth-type forms of LPS was competed for efficiently by lipoteichoic acid and by rough mutant (Ra and R c) forms of ... of bacteria and yeast by hemolin may be due to binding and crossing-linking of these micro-organisms by hemolin. Binding of hemolin to bacteria and yeast cells...

Ngày tải lên: 31/03/2014, 09:20

... the pat- terns of protein binding to the 5¢-UTR or 3¢-UTR dif- fer significantly, although some proteins seem to bind to both; (b) the pattern of 5¢-UTR and 3¢-UTR protein binding of PMA-treated ... found to mediate these effects of cobalt and nickel. Post-transcriptional regulation was associated with qualitative and quantitative changes in the binding of specific...

Ngày tải lên: 16/03/2014, 05:20

... natural ligand of bovine odorant -binding protein. J Biol Chem 276, 715 0–7 155. 26 Wiseman T, Williston S, Brandts JF & Lin L-N (1989) Rapid measurement of binding constants and heats of binding ... energy of binding (D G °) exceeded the heat of binding (DH°) by more than a factor of two (Table 1), indicating that binding to por- cine odorant binding protei...

Ngày tải lên: 07/03/2014, 16:20

... Graph Model 15, 13 2–1 34. C. L. Jenkins et al. Binding of non-natural 3¢-nucleotides to RNase A FEBS Journal 272 (2005) 74 4–7 55 ª 2005 FEBS 755 Binding of non-natural 3¢-nucleotides to ribonuclease ... aside for the calculation of R free [45]. The 3¢-nucleotide and water mole- cules were modelled using the 2F o –F c and F o –F c SIGMAA weighted maps. The topology and...

Ngày tải lên: 16/03/2014, 18:20

... disturbs the binding of FXIIa to HUVEC by binding to soluble FXIIa. (B) The C1-INH binds to receptor bound FXIIa. Fig. 4. Correlation between amidolytic activity and the amount of FXIIa bound to the ... of Zn 2+ as a result of leakage from disturbed cells. This leakage may lead to binding of FXII and PKK/HK to respective receptors on endothelial cells. Localize...

Ngày tải lên: 23/03/2014, 20:22

... (gp96) and its inhibition by the physiological ligands ATP and Ca 2+ Ming Ying and Torgeir Flatmark Section of Biochemistry and Molecular Biology, Department of Biomedicine, University of Bergen, ... affinity and low stoichio- metry of peptide binding to Grp94 in vitro, and the finding that this binding seems to be almost irrevers- ible, have questioned the propose...

Ngày tải lên: 30/03/2014, 11:20

... concentrations of IVIg: 100 lgÆmL )1 (lines 1–3 ) and 50 lgÆmL )1 (lines 4–6 ). (C) Increased binding of pH 4 buffer- exposed IVIg to recombinant human IFN-c. (D) Increased binding of low-pH buffer-exposed ... recognition of the target antigen. All of these findings allow us to hypothesize that elevated binding to various molecular patterns of monoclonal and...

Ngày tải lên: 16/02/2014, 15:20

... intensities of the di- (d), mono- (j) and nonglycosylated isoform (m) of PrP C were quantified and calcu- lated as percentages of the total signal. The glycoforms of the pro- tein bands were analyzed ... C). b Linear epitope of ovine PrP. c Linear epitope of human PrP. d Recog- nized solid-phase immobilized peptide 12 6–1 64, but failed to bind peptide 14 2–1 60 [50]. G...

Ngày tải lên: 19/02/2014, 02:20