Báo cáo khoa học: Recent contributions of in vitro models to our understanding of hepatitis C virus life cycle pdf
Báo cáo khoa học: Recent contributions of in vitro models to our understanding of hepatitis C virus life cycle pdf
... and selection of quasispecies during the culture of infected hepatocytes. To succeed in obtaining HCV infection in primary human hepatocytes, an existing model of hep- atitis B virus infection ... summary, use of HCV-containing sera to recon- stitute the entire life cycle of HCV in vitro has proved to be very difficult. Although infection of primary cells has be...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo khoa học: A single mismatch in the DNA induces enhanced aggregation of MutS Hydrodynamic analyses of the protein-DNA complexes pot
... 5¢-GGCTTAGAGCTTAATTGCTGAATCTGGTGCTCGCCTGATAAATTGTGTCGAAATCCGCGA CCTGCTCC ATGTTACTTAGCCGGAACGAGGCGGATTCGCGATTCCTTGATGCCTATGGTGA-3¢ CLE 61 5¢-GCCTCGTTCCGGCTAAGTAACATGGAGCAG GTCGCGGATTTCGACACAATTTATCAGGCGA-3¢ GTE 61 5¢-TCGCCTGATAAATTGTGTCGAAATCCGCGA TCTGCTCCATGTTACTTAGCCGGAACGAGGC-3¢ GCE ... 5¢-TCGCCTGATAAATTGTGTCGAAATCCGCGA TCTGCTCCATGTTACTTAGCCGGAACGAGGC-3¢ GCE 61 5¢-TCGCCTGATAAATTGTGTCGAAATCC...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khóa học: Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells potx
... the speci c binding of HB-19 to surface nucleolin occurs through the arginine-rich basic C- terminal tail of nucleolin [26]. The fact that hLf and HB-19 compete with each other for binding to surface ... binding to nucleolin, suggest that the C- terminal tail of nucleolin should be implicated in the mechanism of binding of Lf to nucleolin. In general, the crosslinking...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Recent insights into cerebral cavernous malformations: the molecular genetics of CCM pot
... the advances in CCM molecu- lar genetics and the remaining gaps in this field. In addition to the identification of CCM genes, a number of recent biochemical in vitro studies and in vivo CCM animal ... families linked to the CCM1 locus [8]. In Caucasian families, the proportions of families linked to each CCM locus were 40% (CCM1), 20% (CCM2) and 40% (CCM3) [7]. The...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Utilizing logical relationships in genomic data to decipher cellular processes pptx
... hereafter as an information coefficient) comparing either the logically combined vectors or individual vec- tors A or B with vector C, conditioned on the infor- mation available in vector C, and where ... regarding which proteins and protein interactions affect a change in measurable phenotypic outcome. Conclusions The ultimate goal of genomics research is to describe the cellular ne...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "Sparse Information Extraction: Unsupervised Language Models to the Rescue" pptx
... research to compare them, as described be- low. To assess each extraction, we determine how sim- ilar its context vector is to a canonical seed vec- tor (created by summing the context vectors of ... poten- tial to improve type checking accuracy. For exam- ple, consider comparing Pickerington, a sparse candidate argument of the type City, to the seed argument Chicago, for which...
Ngày tải lên: 31/03/2014, 01:20
Tài liệu Báo cáo khoa học: A point mutation in the ATP synthase of Rhodobacter capsulatus results in differential contributions of DpH and Du in driving the ATP synthesis reaction pptx
... linear PCR, using the following mutagenic oligonucleotides: 5¢-CGCGATGTATGCGC TC AAGATCCTCGTGGCC-3¢ and 5¢-GGCCACGAGG AT CTTGAGCGCATACATCGCG-3¢. The mutation introduced an additional restriction ... DpH differences the Ôacidic Õ solution contained 20 m M Tricine instead of succinic acid. Assuming complete equilibration of the K + during the 1 h preincubation (see above), the value of t...
Ngày tải lên: 21/02/2014, 03:20
Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc
... CTGAGGTTACAGACAACTGTTC 13cIMH GSP-Rev CCTTTGACATCGCAAGTGGATCA RPE6 5c GSP-Fwd NM_001113653 TTGAGGTGACAGACAATTGCCT RPE6 5c GSP-Rev TCTTTGACTTCTCAAACTGATCG RPE65a-His-Fwd NM_200751 GCGGCCGCCACCATGCATCATCACCATCAC CATGTCAGCCGTTTTGAACAC RPE6 5c- His-Fwd NM_001113653 ... TGCARRAAYATHTTYTCCAG Deg RPE65-Rev AYRAAYTCRWRBCCYTTCCA RPE65a-Fwd NM_200751 GCGGCCGCCACCATGGTCAGCCGTTTTGAACAC RPE65a-Rev GATAT...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... employing this approach, close to 70% inhibition of viral infec- tion was achieved in cell lines stably transduced with an expression vector encoding short hairpin RNA against the CCR5 receptor. Similarly, ... Bruton’s tyrosine kinase; EBV, Epstein–Barr virus; ITK, inducible T-cell kinase; NKT cell, natural killer T cell; PH, pleckstrin homology; PKB, protein kinase B; R2 8C, arginine...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
... 5¢-ACGGCTTCTACGGATCGAA ACT-3¢ for PPARc ,5¢-AAGACAGCTCCTCCTCGAAGG TT-3¢ and 5¢-TGACCAAATCCCCATTTACGC-3¢ for aP2, 5¢-ATCCATGGATGGACGGTAACG-3¢ and 5¢-CTGGA TCCCAATACTTCGACCA-3¢ for LPL, 5¢-TGGGTTGG CTGCTTGTG-3¢ ... 5¢-GCGTGGGCAGGATGAAG-3¢ for SCD, 5¢-GATGTGGAACCCATAACTGGATTCAC-3¢ and 5¢-GGTCCCAGTCTCATTTAGCCACAGTA-3¢ for CD36, 5¢-GCGTCGGGTAGATCCAGTT-3¢ and 5¢-CTC AGTGGGGCTTAGCTCTG-3¢ for ACC, an...
Ngày tải lên: 16/02/2014, 09:20