Báo cáo khoa học: POSTER PRESENTATIONS P1 Functional Genomics, Proteomics and Bioinformatics docx

... compilation ª 2009 Federation of European Biochemical Societies 113 POSTER PRESENTATIONS P1 Functional Genomics, Proteomics and Bioinformatics P1 1 The influence of the HERV-K LTR on KIAA1245 subfamily ... clusters and two subgroups in each cluster; 1: Kirikkale (subgroup1), Beynam, Haymana, Afyon, Konya and Yunak (subgroup2), 2: Aksaray (subgroup1) and Ayas, Kirsehir a...

Ngày tải lên: 16/03/2014, 01:20

... 23 SYMPOSIUM 1: FUNCTIONAL GENOMICS, PROTEOMICS AND BIOINFORMATICS 1.1. Epigenetics: DNA Methylation and Far Beyond IL 1.1–1 The role of MeCP2 in the brain A. Bird, P. Skene, R. Illingworth and J. Guy Wellcome ... viability. E2F2, RBF, and Mip130/LIN-9 acted in opposition to Myb by repressing the expression of Polo and SAC genes in vivo. Remarkably, the absence of both Myb...

Ngày tải lên: 16/03/2014, 01:20

... tailored design of drug candidates. The H1 receptor has an important role in many physiological and pathological processes and a better understanding of its structure and of its ligand interaction pattern ... sufficient for functional and biophysical studies, but for crystalliza- tion studies further purification will be required, e.g. by ligand-affinity chromatography [16,17]. Global...

Ngày tải lên: 30/03/2014, 14:20

... barley and other cereals. 4000 P. Galuszka et al.(Eur. J. Biochem. 271) Ó FEBS 2004 Acknowledgements This work was supported by grants 204/03 /P10 3 and 522/03/0979 from the Grant Agency and M SM ... Hordeum and Triticum, as well as report on the cloning of the fi rst two CKX genes of barley and demonstrate functionality for one of them in transgenic tobacco an d Arabidopsis plants....

Ngày tải lên: 19/02/2014, 16:20

... dimeric ligand [11,12]. This can lead to avidity effects, where ligand affinity is increased by binding simultaneously to two receptor chains. The formation of heterodimeric ligands and ⁄ or multiple ... ligand with membrane receptor chains provide new opportuni- ties for a cell to determine and tune receptor affinity and, therefore, specificity. Combinatorial assemblies of heterodimeric BM...

Ngày tải lên: 15/03/2014, 09:20

... beta, APE1, PARP1 and XRCC1. APE1 can perform stimulation of strand- displacement synthesis catalysed with Pol beta and proofreading function while PARP1 inhibits these reactions. PARP1 inhibits activity ... Nicola 2 and D. J. Hilton 3 1 Cancer and Haematology/Molecular Medicine, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia, 2 Cancer and Haematolog...

Ngày tải lên: 19/02/2014, 07:20

... obtained data demonstrate that the P1 ⁄ P8 A unmodified P2 P3 P4 P5 P6 P7 P9 P10 P11 P12 P13 P14 P15 P16 unmodified P2 P3 P4 P5 P6 P7 P9 P10 P11 P12 P13 P14 P15 P16 0.00 0.25 0.50 0.75 1.00 1.25 1.50 1.75 k ... ligands, because, as we have already suggested, there are at least seven more nonbridging phosphate oxygens, at positions P2, P4, P9, P10 , P11 , P12 and P13 ,...

Ngày tải lên: 07/03/2014, 10:20

... S2, S1, S1¢,S2¢,S3¢, and S4¢) [15]. These are the binding sites for the P4, P3, P2, P1, P1 ,P2¢,P3¢,andP4¢ residues of an octapeptide substrate [16]. Thus the N-terminal and C-terminal parts ... hydroxy group and which is also shorter by one carbon in the central part of the inhibitor [41]. In this structure, the distances between the P1/ P1 benzyl groups and Arg8/Arg108 were 4.0...

Ngày tải lên: 08/03/2014, 02:20

... zebrafish SULT1 ST1 and ST2 mRNAs in cultured zebrafish cells (lanes 1 and 3) and whole zebrafish (lanes 2 and 4) by RT-PCR. The primers used for amplification of zebrafish SULT1 ST1 and 2 were the same ... was from PanVera Corporation (Madison, WI, USA). T 4 DNA ligase and all restriction endonucleases were from New England Biolabs. XL1-Blue MRF¢ and BL21 Escherichia coli host strai...

Ngày tải lên: 08/03/2014, 02:20

... Lexical Ontologies Functional and Context-Sensitive Tony Veale Computer Science and Informatics University College Dublin Ireland tony.veale@ucd.ie Yanfen Hao Computer Science and Informatics University ... safeguards ontological coherence and ensures that only kinds of people or groups can ever be considered as fundamentalists. The example of Figure 1 is hand-crafted, but a functi...

Ngày tải lên: 08/03/2014, 02:21