Báo cáo khoa học: SYMPOSIUM 1: FUNCTIONAL GENOMICS, PROTEOMICS AND BIOINFORMATICS docx

... 23 SYMPOSIUM 1: FUNCTIONAL GENOMICS, PROTEOMICS AND BIOINFORMATICS 1.1. Epigenetics: DNA Methylation and Far Beyond IL 1.1–1 The role of MeCP2 in the brain A. Bird, P. Skene, R. Illingworth and ... carbohydrate specificity, affinity and atomic details of interaction between the two P. aeruginosa lectins and their ligands allowed for the design and synthesis of high affini...

Ngày tải lên: 16/03/2014, 01:20

... PRESENTATIONS P1 Functional Genomics, Proteomics and Bioinformatics P1–1 The influence of the HERV-K LTR on KIAA1245 subfamily gene expression N. Abrarova, E. Stoukacheva, T. Vinogradova and E. Sverdlov Laboratory ... protein and glycoprotein pattern of the secretion, they showed seasonal changes. Protein band numbers and their optic density were high in posthibernation period....

Ngày tải lên: 16/03/2014, 01:20

... Vaidya KS, Francis TA & Kikly K (2000) Potent and selective non- peptide inhibitors of Caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J Biol Chem 275, 16007–16014. 26 Hotchkiss ... cold- and ischemia-induced apopto- sis in donor livers and reduces sinusoidal endothelial cell apoptosis and caspase-3 activity by 94%. It has recently been granted orphan drug...

Ngày tải lên: 07/03/2014, 11:20

... [23]. Rap1 and ICAP-1 regulate Krit1 localization to microtubules and membranes Among the FERM family members, ERM proteins and talin provide a regulated linkage between mem- brane proteins and the ... Bou- vard, Julie Milanini, Michel Franco and Eric Macia for useful discussions and critical reading. We thank D. A. Marchuk for providing us with Krit1 and ICAP-1 cDNAs, and J....

Ngày tải lên: 16/03/2014, 05:20

... calcium-dependent intracellular signalling. Materials and methods DNA constructs Coding sequences of mouse copines-2 and -6, and human copines-1, -3 and –7, were derived from image clones: IMAGE:3985959, ... copines-1–6 has shown that copines- 1, -2 and -3 are ubiquitous, whereas copine-4 has a more restricted distribution in brain, heart and pros- tate gland, and copine-6 is br...

Ngày tải lên: 29/03/2014, 21:20

... of spelling errors and their corrections by logging keystrokes and extract- ing the pre- and post-correction strings from them. By learning the characteristics of corrected and un- corrected errors, ... as puclic→public and otigaga→otibaga. 5 Conclusion We have presented our collection methodology and analysis of error correction logs across error types (corrected vs. uncorrected)...

Ngày tải lên: 19/02/2014, 19:20

... membrane and cytosolic fraction, respectively, antibodies against actin (mouse monoclonal, 1:4 000, Sigma), lamin C (rabbit poly- clonal, 1:1 000, Abcam), MnSOD (rabbit polyclonal, 1:2 000, Sigma) and ... 2,3 and 4, lower band). The levels of mutant and wild-type MCPIP mRNAs were higher when these vectors were co-transfected with a vector overexpress- ing IL-1b (Fig. 5, lanes 3 an...

Ngày tải lên: 18/02/2014, 14:20

... antigen-presenting cells and activate T cells in vitro in an antigen-specific and MHC-restricted manner [32], especially in the presence of cytokines. Natural ligands of ICAM- 1and LFA-1 are expressed on ... forskolin (Sigma) and 20 ngÆmL )1 neuregulin A B Fig. 5. Activation of MAPKs in LPS-stimulated SCs. (A) Immuno- blots were probed for phosphorylated ERK, p38 and JNK (p-ERK, p-p38...

Ngày tải lên: 18/02/2014, 18:20

... 60 kDa band, if specific, represents a truncated, nonfunctional, intra- cellular P2X 7 protein. We therefore assumed that the 80 kDa band represents mature, functional P2X 7 Caveolin-1 and P2X 7 expresssion ... nonspecific band. However, immunoreactivity to both the 80 kDa and 60 kDa bands was abolished following preincubation with the antibody control peptide (Fig. 1D), implying that the...

Ngày tải lên: 19/02/2014, 00:20

... glucose and hemin chloride (13 lgÆmL )1 ), and further incubated at 30 °C for 24 h. Then, the cells were collected and suspen- ded in 25 mL of 40% potassium hydroxide and 25 mL of methanol and refluxed ... ⁄ GAL10) from pESC- CYP93E1 was separated upon agarose gel electrophoresis and ligated into SalI and ClaI-digested and dephosphory- rated pESC-PSY. The resulting plasmid was...

Ngày tải lên: 19/02/2014, 07:20