... aA-crystallin requires this domain [66]. Attachment ofR116C aA-crystallin to Hsp27 and aB-crystallinincreases in comparison to wild type, while binding tocC-crystallin and bB2-crystallin decreases. ... opaque with age and contain many inclusion bodies reactive with antibodyto aB-crystallin, but not to b- and c-crystallin, suggest-ing an important role for aA-crystallin in maintaininglens transparency ... deficient in desmin, again demonstrating inclusion body construc-tion independent of intermediate fialments [62]. Inter-estingly, inclusion body formation is slowed byaB-crystallin, Hsp27 and HspB8,...