Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx

... 5609 Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism Roma ... Dehydroepiandrosterone inhibits the prolifera- tion of HUVEC by enhancing the expression of p53 and p21, restricting the phosphor...

Ngày tải lên: 16/03/2014, 00:20

... also implicated in the mechanism of PTN binding to cells. This is somewhat analogous to the mechanism of HIV binding cells in which both heparan and chondroitin sulfate proteoglycans and nucleolin ... coordination of at least two events implicating on the one hand heparan sulfate proteo- glycans [6,7] and on the other hand the cell surface- expressed nucleolin [4...

Ngày tải lên: 30/03/2014, 20:20

... help translate the cellular and biochemical insights into a better understanding of disease mechanism. In this minireview, we discuss the contributions of animal models to our growing understanding of the ... models are relevant to disease to the degree that they help us further understand the human phenotype. Recent investigations have further refined our under- standing o...

Ngày tải lên: 15/03/2014, 10:20

... that the 5¢-UTR and 3¢-UTR of CfNR allow control of both the timing and level of expression of introduced genes in transgenic C. fusiformis. Results Increasing the efficiency of C. fusiformis transformation Previously, ... Structure of transformation plasmid pNICgfp and analysis of GFP expressing C. fusiformis transformants. (A) Restriction map of the part of pl...

Ngày tải lên: 07/03/2014, 21:20

... membrane in the cells, although we cannot exclude the possibility of the involvement of some GLUT isoform(s) other than GLUTs1–4. Glucose uptake and GLUT1 expression are enhanced in cancer cells and ... in RGM-1 cells, mouse 3T3-L1 fibroblasts, and 3T3-L1 adi- pocytes, and investigated the mechanism of the novel function of DIF-1. We show here that DIF-1 indu...

Ngày tải lên: 23/03/2014, 09:20

... follows: An f feature of the D description can have either a single value or a set of values. An f feature of the D description has compatible values in the E description iffone of the values of ... [ADV] way of handling compounding and adequate han- dling of derivational affixes. Recent implementations of Humor 99 define the set of possible morpheme s...

Ngày tải lên: 23/03/2014, 19:20

... follows: An f feature of the D description can have either a single value or a set of values. An f feature of the D description has compatible values in the E description iffone of the values of ... [ADV] way of handling compounding and adequate han- dling of derivational affixes. Recent implementations of Humor 99 define the set of possible morpheme s...

Ngày tải lên: 23/03/2014, 19:20

... biosynthesis of PC in HepG2 cells at the level of CT activity. It interferes with the translocation process of CT from the cytosol to the membrane and finally leads to an inhibition of the biosynthesis ... oleate activates the PC synthesis in HepG2 cells increasing the CT activity. Thence, in another set of experiments we assayed the combined effect of HePC...

Ngày tải lên: 17/03/2014, 11:20

... F 0 , F c and DF max represent the fluorescence intensity of tubulin in the absence of rotenone, the fluorescence intensity of tubulin in the presence of different concentrations of ligand and the maximum ... significant insight with respect to the antiproliferative mechanism of action of rotenone. Results Effects of rotenone on the proliferation HeLa and...

Ngày tải lên: 07/03/2014, 05:20

... the differentiation of skin cancer cells with subsequent inhibition of proliferation [16], and induction of cell death was mediated via P2X 7 receptors in skin cancer and prostate cancer cells [16,17]. The formation ... LXF-289 cells in the presence of ATP. These anticancer substances inhibit cell cycle progression by different mechanisms and form the bas...

Ngày tải lên: 07/03/2014, 12:20