Báo cáo khoa học: Molecular basis of cytokine signalling – theme and variations docx
Báo cáo khoa học: Molecular basis of cytokine signalling – theme and variations docx
... on the mole-
cular basis of cytokine receptor signalling – theme and
variations – has three movements, like a sonata. First,
we will look at the basic mechanism and the many
variations realized ... 67 4–6 76.
Molecular basis of cytokine signalling W. Sebald et al.
118 FEBS Journal 277 (2010) 10 6–1 18 ª 2009 The Authors Journal compilation ª 2009 FEBS
T...
Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc
... some of
the key findings that have led to our current under-
standing of the molecular mode of action of glypho-
sate and the molecular basis for glyphosate resistance.
Structure and function of ... (Arg21, Arg111, and His138) and with the
carboxylate end (Arg21 and Arg73) of GriP. Of partic-
ular note is a short, 2.46-A
˚
hydrogen bond between N-
e of His138 a...
Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... 102 3–1 034.
N. Numa et al. Molecular basis of perinatal form of hypophosphatasia
FEBS Journal 275 (2008) 272 7–2 737 ª 2008 The Authors Journal compilation ª 2008 FEBS 2737
Molecular basis of perinatal ... lane:
14
C-methylated protein markers of 200, 97.5, 66, 46 and 30 kDa, from the top of
the gel.
N. Numa et al. Molecular basis of perinatal form of hypophos...
Báo cáo khoa học: Molecular basis of toxicity of Clostridium perfringens epsilon toxin ppt
... is
a b-sandwich, containing a five-stranded sheet and a
b-hairpin (both of which are anti-parallel). The third
domain is a b-sandwich composed of one four-
stranded sheet and one three-stranded ... cell
specificities of aerolysin and e-toxin, and the different
function of LSL, is the result of the different structures
and properties of these domains.
The second and third...
Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc
... the yeast and amebal PGKs.
3D predicted model of EhPGK
Predicted 3D structures of the EhPGK were obtained
by means of modeller software (see Fig. S1 for details
on these models) and molecular ... mechanism and determinants of
thermal stability. Structure 5, 147 5–1 483.
34 Scopes RK (1978) Binding of substrates and other
anions to yeast phosphoglycerate kinase. Eur J Bio...
Báo cáo khoa học: Molecular basis of cerebral neurodegeneration in prion diseases pdf
... symptoms, and propagation of
infectious prions, the latter giving rise to the typical
transmissibility within and between species [ 1–5 ]. The
formation of the disease-associated isoform of prion
protein ... the cellular func-
tion of the normal cellular isoform of prion protein is not exactly known,
the impact of gain of toxic function or loss of function, or a combinat...
Báo cáo khoa học: Molecular characterization of secretory proteins Rv3619c and Rv3620c fromMycobacterium tuberculosisH37Rv docx
... comparative analysis of thermodynamic parameters of ESAT–CFP-10, Rv0287–Rv0288, and Rv3619c–Rv3620c. The stoichiome-
try of interaction and values of K
b
and DH were determined by ITC. DG and DS were ... contents of Rv3619c, Rv3620c and
the 1 : 1 complex were approximately 33%, 34% and
70%, respectively. The secondary structure of
Rv3619c–Rv3620c was very similar to th...
Báo cáo khoa học: Molecular cloning of the ecdysone receptor and the retinoid X receptor from the scorpion Liocheles australasiae pot
... suppressalis EcR-A
Fig. 2. Alignment of the primary sequences of (A) A ⁄ B regions of EcRs, (B) E regions of EcRs, (C) A ⁄ B regions of USPs and RXRs, and (D)
E regions of USPs and RXRs. Alignments were ... region) and E ⁄ F (ligand- or hormone-binding
domain) [8,9]. The X-ray crystal structures of the
ligand-binding domains of EcR, USPs and RXRs have
been resolved i...
Báo cáo khoa học: Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases pptx
... arrowheads to the right of the gels, and their
complexes 1–4 to the left. Bands 1 and 2 correspond to 1 : 2 and 1 : 1 DD–DDR complexes, respectively, and bands 3 and 4 to GD–GDR
and GD–DDR complexes, ... dehydratase (A–D) and apoglycer-
ol dehydratase (E–H) (0.74 unit) were preliminarily incubated without (broken lines in A,E) and with (solid lines) 23 lg of GDR (B–D) a...
Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1.1 to 1.6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx
... the protein databank as
2AOD (WT–p2-NC), 2AOC (I84V–p2-NC), 2AOE (V82A–
CA-p2), 2AOF (V82A–p1-p6), 2AOG (V82A–p2-NC), 2AOH
(V82A–p6-PR), 2AOI (WT–p1-p6) and 2AOJ (WT–p6-PR).
Acknowledgements
This ... complexes PR–p1-p6,
PR
V82A
–p1-p6, PR–p6
pol
-PR and PR
V82A
–p6
pol
-PR, as
described previously [25].
Overall comparison of the crystal structures
Comparison of ligand bound and unli...