Báo cáo khoa học: CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin doc
Báo cáo khoa học: CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin doc
... November 2009) doi :10 .11 11/ j .17 42-4658.2009.07475.x CXXC finger protein 1 (Cfp1), encoded by the CXXC1 gene, is a compo- nent of the euchromatic Setd1A histone H3K4 methyltransferase complex, and is ... restricts the Setd1A complex to euchromatin FEBS Journal 277 (2 010 ) 210 –223 ª 2009 The Authors Journal compilation ª 2009 FEBS 223 CXXC finger...
Ngày tải lên: 15/03/2014, 09:20
Báo cáo khoa học: Human proteoglycan testican-1 inhibits the lysosomal cysteine protease cathepsin L pdf
... to determine the inhibition constant K i due to the tight binding of the protease by the inhibitor and the possibility of modification of the inhibitor bytheenzyme[32].Thesedatawerefittedtothetheoretical equation ... background. The location of the thyropin domain within testican -1 is illustrated relative to the other known domains of testican -1 (not drawn to scale...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: Death-associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death docx
... g.charras@ucl.ac.uk *These authors contributed equally to this work (Received 11 March 2009, revised 20 August 2009, accepted 28 September 2009) doi :10 .11 11/ j .17 42-4658.2009.07 412 .x Death-associated protein ... that recruitment of the cross-linking proteins comes to a steady state. The mechanical work needed to force the cytosol back into the bleb and crumple the ac...
Ngày tải lên: 29/03/2014, 08:20
Báo cáo khoa học: Green fluorescent protein-tagging reduces the nucleocytoplasmic shuttling specifically of unphosphorylated STAT1 potx
... 10 , 13 125 Berlin, Germany Fax: +49 30 94793 17 9 Tel: +49 30 94793 17 1 E-mail: vinkemeier@fmp-berlin.de (Received 21 August 2006, revised 1 December 2006, accepted 6 December 2006) doi :10 .11 11/ j .17 42-4658.2006.05626.x Fluorescence ... redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins. Eur J Biochem 260, 13 7 14 4. 18 Lillemeier BF, Ko ¨ ste...
Ngày tải lên: 30/03/2014, 09:20
Báo cáo khoa học: Replacement of helix 1¢ enhances the lipid binding activity of apoE3 N-terminal domain pot
... USA Fax: +1 510 450 7 910 Tel: +1 510 450 7645 E-mail: rryan@chori.org (Received 3 November 2005, revised 1 December 2005, accepted 5 December 2005) doi :10 .11 11/ j .17 42-4658.2005.05089.x The N-terminal ... relates to the high intrinsic stability of this domain. Denaturation studies revealed that the NT domain is exceptionally stable compared to either the C-terminal doma...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx
... 1. 62 0.39 Glu376 – 1. 64 – 0.57 BH 4 – 2.95 1. 00 Phe377 – 1. 10 0 .12 Phe377 – 1. 11 0 .10 Gly392 – 1. 27 0 .14 Gly392 – 1. 16 0 .16 Ser395 – 1. 32 0.73 Ser395 – 2.38 1. 00 Ser396 – 1. 33 )1. 04 Ser396 – 0.86 ... – 2. 51 – 4. 81 – 4.90 Ser324 – 1. 57 – 3.88 – 3. 31 His3 31 – 0.72 0 .17 Pro325 – 1. 88 – 1. 44 Pro325 – 1. 01 – 1. 40 Trp372 – 1. 53 0.04 Glu326 – 1. 31...
Ngày tải lên: 31/03/2014, 07:20
Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx
... could ARMCX4_HUMAN H1FX_HUMAN H1F0_HUMAN HIST1H1T_HUMAN HIST1H1A_HUMAN HIST1H1B_HUMAN HIST1H1C_HUMAN HIST1H1E_HUMAN HIST1H1D_HUMAN H1fx_MOUSE Hist1h1t_MOUSE Hist1h1a_MOUSE Hist1h1b_MOUSE Hist1h1c_MOUSE Hist1h1e_MOUSE Hist1h1d_MOUSE XP_899364_MOUSE Fig. ... Table 1. MCF7 PTMs compared with HeLa PTMs H1.5: +aK17 H1 .1: )aK22 H1.2, H1.3, H1.4: +aK34 H1.2, H1.3, H1.4: )uK46 H1.2, H1.3, H1.4: )a...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: KCNE4 can co-associate with the IKs (KCNQ1–KCNE1) channel complex ppt
... membrane +++++++– +++++++– +++++++– –+– +–– ––+ KCNQ1 KCNE4 KCNE1 3FLAG 75 kDa 50 IP:KCNQ1 IB:KCNQ1 75 kDa IB:KCNQ1 25 30 kDa IB:KCNE4 25 kDa 15 IB:FLAG 50 kDa 30 25 IP:KCNQ1 IB:KCNE4 30 kDa 25 15 IP:KCNQ1 IB:FLAG 876543 21 910 11 Fig. ... immunoblotting was used to establish that KCNE4 directly associates with KCNQ1, and can co-associate together with KCNE1 in the same KCNQ1 co...
Ngày tải lên: 18/02/2014, 17:20
Báo cáo khoa học: Targeted disruption of one of the importin a family members leads to female functional incompetence in delivery docx
... ⁄ ) mice FEBS Journal 278 (2 011 ) 15 61 15 72 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 15 71 pattern of the importin-alpha protein family. FEBS Lett 417 , 10 4 10 8. 39 Rodriguez CI, Buchholz ... Acad Sci USA 90, 11 117 11 1 21. 26 Pentecost BT & Teng CT (19 87) Lactotransferrin is the major estrogen inducible protein of mouse uterine secre- tions. J Biol Che...
Ngày tải lên: 28/03/2014, 23:20
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... by using the DE- 81 filter paper S103 Y 112 R207 /19 9 K173 /16 5 G145/D137 D142 /13 4 E1 41/ 133 L75/67 D2 01/ 193 G77/69 G197 /18 9 G145/D137 A B Fig. 2. Superposition of PRTFDC1 with HPRT-ImmGP (Protein Data ... 2.0 10 .5 ± 0.9 2.9 · 10 6 ± 1. 0 · 10 6 (10 0%) Guanine PRTFDC1 36 .1 ± 14 .3 2.9 ± 0.7 1. 36 ± 0.34 3.9 · 10 4 ± 9.3 · 10 3 (0.09%) HPRT 9.9 ± 0.2 899 ± 11 7 4...
Ngày tải lên: 15/02/2014, 01:20