... whether the SLexlevel of InR on insulin-responsive cells in diabeticpatients was changed. This may reveal the role of the sugar chains on InR in the pathogenesis of diabetes.In summary, the ... receptor (EGFR) on the cell surface and incells, as well as the sialyl Lewis X (SLex, the product of a1,3-FucT-VII)content of the EGFR were unchanged. However the level of SLexon the InR a subunit ... However, all the above-mentioned structural changes in receptor glycansare located in the core portion of N-glycan, and whe-ther alteration of the terminal residue on the outerchain of either N-orO-glycan...