Báo cáo khoa học: Phosphorylation mechanism and structure of

Báo cáo khoa học: Phosphorylation mechanism and structure of serine-arginine protein kinases pot

... SRPK1 and SRSF1, together with crystal structures of SRPK1 bound to peptide and protein substrates and the recent structures of CLK1 and CLK3, suggest an elegant mechanism of recognition and phosphorylation ... ARTICLE Phosphorylation mechanism and structure of serine-arginine protein kinases Gourisankar Ghosh 1 and Joseph A. Adams 2 1 Department of C...

Ngày tải lên : 15/03/2014, 00:20

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Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulﬁde isomerase family proteins with nonclassic active center motifs pdf

... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. ... organelle and membrane proteins are synthe- sized and folded with the assistance of molecular chap- erones and other folding factors in the endoplasmic reticulum (ER...

Ngày tải lên : 18/02/2014, 11:20

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Báo cáo khoa học: "CONTROL STRUCTURES AND THEORIES OF INTERACTION IN SPEECH" potx

... CONTROL STRUCTURES AND THEORIES OF INTERACTION IN SPEECII UNDEP~.WI'ANDING SYSTEMS E.J. Briscoe and B.K. Boguraev University of Cambridge, Computer Laboratory ... temporal distribution of various types of information in speech were different. The architecture we propose is developed from a study of the task of speech, unde:standing and, furthermore, is ... kinds of...

Ngày tải lên : 08/03/2014, 18:20

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Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt

... unsupervised learning neural network. Protein Eng 6, 383–390. 27 Fersht A (1999) Structure and Mechanism in Protein Science: a Guide to Enzyme Catalysis and Protein Folding, p. 208. W.H. Freeman, ... content of b -structure The first UV-absorption (Fig. 4A), fluorescence (Fig. 4B) and CD spectra (Fig. 4C,D) of a plant PLD reflect the properties of a common protein. Obviou...

Ngày tải lên : 19/02/2014, 02:20

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Báo cáo khoa học: Puriﬁcation and characterization of zebraﬁsh hatching enzyme – an evolutionary aspect of the mechanism of egg envelope digestion pot

... min, bands with molecular masses of 43 and 39 kDa were observed in addition to undigested bands of ZP2 and ZP3. After incubation for 10 min, three major bands with molecular masses of 43, 39 and ... and swells the envelope. The cross-species digestion using enzymes and substrates of zebraﬁsh and medaka revealed that both ZHE1 and MHCE cleaved the same sites of the eg...

Ngày tải lên : 07/03/2014, 04:20

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Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx

... K d and k off . The fol- lowing experiments were performed as a ﬁrst approach to ﬁnd the variation in k off as a function of the iNOS substrate structure. Kinetics of the binding of guanidines and N-hydroxyguanidines ... association and dissociation rate constants (k on app and k off app ) for the binding of guanidines and N-hydroxyguanidines to iNOS oxy in the presence o...

Ngày tải lên : 16/03/2014, 22:20

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Báo cáo khoa học: Identiﬁcation and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis potx

... studies of Mosimann et al. [12], the hydroxyl group of Tyr179 lies within hydrogen-bonding distance of O7 and O9 of the glyceryl moiety of Neu5Ac, and a network of noncovalent bonds between enzyme and ... change of activity of wild-type CNS and mutants upon the addition of MgCl 2 to a concentration of 10 mM. The rate of reaction for each variant using 154 l M CTP...

Ngày tải lên : 22/03/2014, 21:21

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Tài liệu Báo cáo khoa học: Afﬁnity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

... of lipo- proteins, and there was a corresponding increase in the binding of [ 125 I]TC-PCSK9 and [ 125 I]TC-PCSK9- D374Y. Second, the extent of speciﬁc binding of both [ 125 I]TC-labeled ligands ... courses and effects of unlabeled ligands and low pH on the dissociation rates of [ 125 I]TC-PCSK9 (A) and [ 125 I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to equilibrium...

Ngày tải lên : 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebraﬁsh, Danio rerio docx

... expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and mouse ... domain of t-bet, the STAT protein interaction domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-ﬁnger d...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt

... conditions of overnutrition, SREBP-1c expression is elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesis are enhanced in the liver and adipose tissues. Intake of energy ... physiology and pathophysiology of the SREBP family Hitoshi Shimano Department of Internal Medicine (Endocrinoglogy and Metabolism), Graduate School of Comprehensive Hum...

Ngày tải lên : 18/02/2014, 13:20

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