Báo cáo khoa học: Oligomannose-coated liposomes efficiently induce human T-cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant doc

... Tax. In this study, we demonstrated that OML ⁄ Tax strongly induced the HTLV-1-specific CD8+ T- cell response without adjuvant in HLA-A*0201 Tgm and HTLV-1 carriers. These results suggest that OML ⁄ Tax is ... Oligomannose-coated liposomes efficiently induce human T- cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant Tomohiro Kozako 1,2 , Sh...

Ngày tải lên: 14/03/2014, 23:20

... color-coded according to electrostatic potentials. Preliminary docking of FVa Arg506 into the catalytic cleft of APC suggests that the 37 loop may interact with the FVa D578 area (see text). Docking of ... respectively. These values are in reasonable agreement with the rate constants obtained from fitting the time courses of FVa inactivation (cf. Figure 1, Table 1). These data suggest that, un...

Ngày tải lên: 19/02/2014, 13:20

... substituted by the codon for Ala. The template used was the recombinant plasmid pET11a ⁄ hpnap, and the primers used for the PCR were 5¢-GGTGCCTTTCACA TTCCACGCGAAGTTATGCACTTTCAT-3¢,5¢-AATTTC TTCAGTGGCTTTCGCCACATTGAAAAAATCGGT-3¢, 5¢-GATCCTTTCAGCGAGATCCGCAAACATGTCCGC AAACTC-3¢ ... 5¢-GGTGCCTTTCACA TTCCACGCGAAGTTATGCACTTTCAT-3¢,5¢-AATTTC TTCAGTGGCTTTCGCCACATTGAAAAAATCGGT-3¢, 5¢-GATCCTTTCAGCGAGAT...

Ngày tải lên: 30/03/2014, 04:20

... which is the lowest among the three fatty acids studied (Table 2). Structure–function relationships In an attempt to identify the site of action of the fatty acids in the plasmin molecule, the amidolytic ... different fatty acids are still unexplored. It was therefore of interest to examine the effects of various potentially relevant fatty acids on plasmin. The three most abundant fatty acids...

Ngày tải lên: 18/02/2014, 17:20

... apparent dissociation constant by Eqn (1). By assuming that the sample is saturated with Tb 3+ at the starting point of the competition, the Ca 2+ -binding affinity is further obtained using the ... a previous observation that these mutations in the intact STIM1 molecule led to constitutive activation of CRAC channels even without store depletion [4]. The canonical EF-hand in STIM1 has been...

Ngày tải lên: 07/03/2014, 00:20

... Sup- 237 port Vectors, associated weights α i , and a constant b. The Support Vectors are a subset of the training feature vectors, and together with the weights and b they define a hyperplane that optimally ... features of the current instance is active in a support vector, this vector is taken into account in the sum calculation, and the common features are active in many support vectors. On...

Ngày tải lên: 17/03/2014, 02:20

... two translation tasks. The correlation with human assessment will be measured for several different statistical MT systems. We will see that the new measure significantly outperforms the existing ... the sentences is five. In contrast, the best Levenshtein path contains one deletion edge, four identity and five consecutive substitution edges; the Levenshtein distance between the two sentences...

Ngày tải lên: 17/03/2014, 22:20

... extramitochondrial H 2 O 2 assay. The experiments reported in the present study were developed to investigate the hypothesis that the intramitochondrial GSH-dependent antioxidant system interferes significantly with the extramitochondrial H 2 O 2 assay, ... pretreatment with CDNB (Fig. 3, succinate + rotenone + AA uncorrected), supporting the contention that CDNB pretreatment corrects for most...

Ngày tải lên: 22/03/2014, 21:21

... to an abstract state of A. By definition the abstract state is sufficient to generate the complete state and its outgoing arcs. We then push those target states of all outgoing arcs onto the stack ... composition uses tuples of states of the two in- put transducers to describe states of the target trans- ducer. Other operations defined on weighted finite- state automata use different abstract sta...

Ngày tải lên: 23/03/2014, 19:20

... ngfldi ta tai trd cho nen kinh te, gan vdi truyen thong trd thanh mgt bg phan thdng tri the gidi, nhit la d cae nfldc thuge The gidi thfl 3 la nhflng nfldc hi tae dgng manh, nhfl My La tinh. Nd tac ... nao, phat trien nao, thinh vfldng nad? Tdi dge trong mgt tap ehi mgt loat bai viet ve Viet Nam trong tfldng lai. Toi thay hg chi ban thong qua GDP, khong ndi gi ve tai hga moi trfldng. Toi...

Ngày tải lên: 17/02/2014, 05:20