Báo cáo khoa học: Modular metabolic control analysis of large responses in branched systems – application to aspartate metabolism potx

... 2011 The Authors Journal compilation ª 2011 FEBS Modular metabolic control analysis of large responses in branched systems – application to aspartate metabolism Fernando Ortega 1 and Luis Acerenza 2 1 ... framework of metabolic control analysis (MCA) [ 1–5 ]. Metabolic networks of organisms show thousands of variable concentrations and fluxes, so...

Ngày tải lên: 14/03/2014, 23:20

... (2007) 18 8–2 01 ª 2006 The Authors Journal compilation ª 2006 FEBS 201 L. Acerenza and F. Ortega Metabolic control analysis of large responses Modular metabolic control analysis of large responses The ... determination of control coeffi- cients in metabolic control theory. Eur J Biochem 188, 32 1–3 25. 9 Schuster S, Kahn D & Westerhoff HV (1993) Mo...

Ngày tải lên: 30/03/2014, 10:20

... Sentiment Analysis of Modern Standard Arabic Muhammad Abdul-Mageed Department of Linguistics & School of Library & Info. Science, Indiana University, Bloomington, USA, mabdulma@indiana.edu Mona ... Computational Learning Systems, Columbia University, NYC, USA, mdiab@ccls.columbia.edu Mohammed Korayem School of Informatics and Computing, Indiana University, Bloomington, USA...

Ngày tải lên: 20/02/2014, 05:20

... 1 c-Actin Actin, cytoplasmic 1 Tubulin b Tubulin a Ankyrin repeat domain-containing protein 18A Ankyrin repeat domain-containing protein 18A Heat-shock protein b1 a-Actin-2 Unclassified Keratin, ... C a-Actinin-2 a-Actinin-3 Desmin VASP Myosin-2 Myosin-3 Myosin-7 (myosin heavy chain 7) Myosin-7 Myosin-9 Myosin-9 Myosin-11 Myosin-13 Myosin-13 Myosin light polypeptide 3 Myosin light polypeptide...

Ngày tải lên: 06/03/2014, 22:21

... known of the func- tion of mRNAs in human spermatozoa, it was difficult to estimate whether the rest of the genes were related to the function of human spermatozoa, or just retained during spermatogenesis. ... transcription–PCR analysis of unknown serial analysis of gene expression tags; rSAGE, reverse serial analysis of gene expression; SAGE, serial analysis of g...

Ngày tải lên: 07/03/2014, 04:20

... Asp140, whichappearstobecrucialinChiBandinchitinaseA1 from Bacillus circulans, whereas it may be mutated to asparagine without loss of activity in other family 18 chitinases [28,30]. Preliminary results of a ... optimum. Chitin, a b-1,4-linked polymer of N-acetylglucosamine (GlcNAc), is degraded in nature by chitinases and b-N- 1-4-acetylhexosaminidases (chitobiases). On the basis...

Ngày tải lên: 07/03/2014, 14:20

... Pex1pN–ProteinA, Pex1pN + D1–ProteinA, Pex1p–ProteinA, Pex6pN–ProteinA, Pex6pN + D 1– ProteinA, Pex6p–ProteinA. For this purpose, we generated strains that express the proteins of interest, C-terminally ... that a mutation in the beginning of Pex1pD2 (G843D in human, corresponding to G700 in yeast) attenuates the interaction of the two AAA-peroxins [23]. To identify the Pex...

Ngày tải lên: 07/03/2014, 16:20

... structure of TenA. (A) Amino acid sequence of HP-TenA. The beginning and end of secondary structure elements of HP-TenA are shown in the bottom line. (B) Stereo view of a cartoon representation of the ... formyl aminopyr- imidine, a degradation product of thiamin, to synthe- size hydroxypyrimidine, which constitutes a building block in thiamin biosynthesis [3]. One of th...

Ngày tải lên: 16/03/2014, 00:20

... kinase inhibitors act by inhibiting the activation of intracellular signal trans- duction, typically by blockage of the ATP-binding site in the catalytic domain of the kinase. As the majority of kinase ... gastroin- testinal stromal tumors, owing to its inhibitory activity against c-kit, the protein tyrosine kinase that is dys- regulated in that cancer. Nevertheless, profiling ki...

Ngày tải lên: 16/03/2014, 00:20

... 32 5290 45 Nicotinonitrile k cat (s )1 ) 131 – – – – K m (mM) 0.12 – – – – k cat /K m (s )1 Æm M )1 ) 1090 – – – – Isonicotinonitrile k cat (s )1 )9 0– – K m (m M ) 0.079 – – – – k cat /K m (s )1 Æm M )1 ) ... of refinement of the aY114T structure, a cobalt atom was added to the model, according to the F o –F c map. The coordinates a...

Ngày tải lên: 16/03/2014, 16:20