Day one nucleic acid structure and function
Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... beingrepositioned sideways, and linker histones are depleted[223]. Once DHSs at enhancers and promoters havebeen created, they invariably incorporate the varianthistones H3.3 and H2A.Z either ... transcriptionally competent and repressedgenes. EMBO J 9, 3997–4006.97 Woodcock CL, Skoultchi AI & Fan Y (2006) Role oflinker histone in chromatin structure and function: H1stoichiometry and nucleosome ... higherorder structures, and both the core histone tails and linker histone H1 (or H5) play major roles in main-taining higher order chromatin condensation [36–38].However, even in the absence of histone...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... CD2-1-6 (amino acids 702–767), CD2-1-7 (amino acids 668–767), CD2-1-8 (amino acids 635–767), CD2-1-6-1 (amino acids 702–735), CD2-1-6-2 (amino acids 702–744) and CD2-1-6-3 (amino acids 702–755). ... CD2-1 (amino acids 600–767) derivatives: CD2-1-1 (amino acids 600–634), CD2-1-2 (amino acids 600–667), CD2-1-3 (aminoacids 600–701), CD2-1-4 (amino acids 600–734), CD2-1-5 (amino acids 735–767), ... into five subregions: KIND2-1 (amino acids 456–487),KIND2-2 (amino acids 456–521), KIND2-3 (amino acids 456–555),KIND2-4 (amino acids 488–620) and KIND2-5 (amino acids589–620). These KIND2 subregions...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... benthic ones, where most of our own work has been based, and two data sets in particular: the invertebrate food webs from an acidic pond(Skipwith Pond, Warren, 1989) and an acidic woodland stream ... NewZealand: New Zealand Limnological Society,pp. 53–74.Thompson, R. M. & Townsend, C. R. (2004).Land-use influences on New Zealandstream communities: effects on speciescomposition, functional ... organization, and food-web structure. New ZealandJournal of Marine and Freshwater Research, 38,595–608.Thompson, R. M. & Townsend, C. R. (2005).Energy availability, spatial heterogeneity and ecosystem...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... active at acidic pH, are specifically inhibited bypepstatin and have two aspartic acid residues responsible forthe catalytic activity [2,5]. However, there are severalstructural and functional ... scutella [84].During daylily petal senescence and cell death, severalgenes were shown to be strongly upregulated. One of thesedaylily senescence-associated genes encodes an AP and itwas suggested ... regionNucellin-like Acidic-hydrophobic-DTG-serine-acidic Cys-rich sequence between Asp32 and Tyr75QCYDE before Tyr75Atypical Hydrophobic-hydrophobic-DTG-serine-acidic Cys-rich sequence between Asp32 and Tyr75Cysteine...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... A., Jones, A., Adams, D.J., Alewood,P.F. & Lewis, R.J. (2004) Chemical and functional identification and characterization of novel sulfated a-conotoxins from the conesnail Conus anemone. ... a-conotoxins MII and AuIB further dissected and correlated the combinato-rial and functional heterogeneity of the slowly decayingpopulation [77]. In this study, two long events of 25 pS16 and 40 pS ... theusefulness of a-conotoxins in the determination of the structure and function of native nAChRs, and indicatethat selectivities and potencies found on oocyte-expressednAChRs can be extrapolated...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... (1999) Structure, function and evolution of an tifreeze proteins. Cell Mol. Life Sci. 55 , 271 –283.11. Yeh, Y. & Feeney, R.E. (1996) Antifreeze proteins: Structures and mechanisms of function. ... [31,32,36] and their three-dimensional structures were determined [34,37–40]. Insubsequent sections, we describe the structure and dynamicsof each protein, and present a comparison of s bwAFP and TmAFPwitheachotherandwithproteinsthathaveasimilar ... and TmAFPwitheachotherandwithproteinsthathaveasimilar fold. Structure of sbwAFP and TmAFPThe structure of sbwAFP has been determined by X-raycrystallography to 2.5 A˚ and by NMR at both 30 °Cand5 °C...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... three antiparallel strands (1, 2 and 7) and strand 6, which is parallel to strand 2. b-Strands arelocated between the four a-helices (a1, 278–294; a2,305–313; a4, 374–381; and a5, 397–405), with ... and 15N atoms of the protein backbone, and formore than 78% of the side chain atoms.The main set of backbone u and w dihedral angles wascalculated from the chemical shift values of backboneatoms13Ca,13Cb,13C¢,1Ha,1HN, ... refinement of NMR and X-ray structures of proteins and nucleic acids. J MagnReson 125, 171–177.52 Laskowski RA, Rullmannn JA, MacArthur MW,Kaptein R & Thornton JM (1996) AQUA and PRO-CHECK-NMR:...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... dublin TLP and zebrafish TLP are found in the flex-ible portions of strands B and C that protrude towardsthe solvent and in the conformation of the long loopconnecting strands D and E [17]. ... evolution of the structure and the function of thethyroid hormone (TH) distributor, transthyretin, hasbeen well researched. The primary, secondary, tertiary and quaternary structures of this ... bacteria) on media containinguric acid as the principal source of nitrogen [18].Purines are major components of nucleic acids and nucleotides. Subsequently, de novo and salvage path-ways for purine...
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Báo cáo khoa học: Structure and function of KH domains docx
... comprising the a1-helix and a2-helix and theb2-strand of KH2. Hydrogen bonds to both amino acid side-chains and the protein backbone, electro-static and polar interactions and, to a lesser extent,hydrophobic ... lineconnecting the b2-strand and b¢-strand rep-resents the variable loop. The white lineconnecting the a1-helix and the a2-helixrepresents the GXXG loop.R. Valverde et al. Structure and function of KH ... entries 2ATW and 2ASB).Although the total number of structures in the Pro-tein Data Bank of KH domains bound to cognate nucleic acid ligand is small, some common features of nucleic acid recognition...
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Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx
... Baum, O. (1997) Thebiology of sialic acids. Insights into their structure, metabolism and function in particular during viral infection. In Glycoscience,Status and Perspectives (Gabius, H J. & ... regulation.GlcNAc kinase has been cloned from man [8] and mouse[9]. Like N-acetylgalactosamine kinase [10] and N-acetyl-mannosamine kinase, as a part of the bifunctional enzymeUDP-GlcNAc 2-epimerase/N-acetylmannosamine ... numberof functionally relevant cysteines was quantified to two, and dithiol-modifying reagents predicted a structural vicinity ofthese cysteines. The amino acid sequences of murine and human...
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