Báo cáo khoa học: Insufficient hydrogen-bond desolvation and prion-related disease ppt
Báo cáo khoa học: Insufficient hydrogen-bond desolvation and prion-related disease ppt
... PAPER
Insufficient hydrogen-bond desolvation and prion-related disease
Ariel Ferna
´
ndez*
Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA
A structuring and eventual ... observation, a physico-
chemical basis for prion-related molecular diseases is
proposed.
MATERIALS AND METHODS
First, I systematically inspected the desolvation patterns of
b...
Báo cáo khoa học: "Efficient Staggered Decoding for Sequence Labeling" pptx
... 1185–
1192.
Fei Sha and Fernando Pereira. 2003. Shallow parsing
with conditional random fields. In Proceedings of
HLT-NAACL, pages 134–141.
Sajid M. Siddiqi and Andrew W. Moore. 2005. Fast
inference and learning ... the
n-th column such that y
n
∈ I(z
n
), and we can use
λ(z
n
) and
¯
λ(z
n
) instead of λ(y
n
) and
¯
λ(y
n
).
We compute λ(y
n
) and
¯
λ(y
n
) by using the
forward...
Tài liệu Báo cáo khoa học: "REPRESENTING KNOWLEDGE ABOUT KNOWLEDGE AND MUTUAL KNOWLEDGE" ppt
... say individual concepts
and propositions and not referents and
truth values. We bear in mind that a seman-
tic network is a graph whose nodes repre-
sent individuals and whose oriented arcs ... system can
reason about intensional concepts like know-
ledge and belief. A problem resolver must
understand the concept of knowledge and know
for example what knowledge it needs to...
Báo cáo khoa học: "A Statistical Tree Annotator and Its Applications" pptx
... favorably with those in (Blaheta
and Charniak, 2000). Lintean and Rus (2007a; Lin-
tean and Rus (2007b) also studied the function tag-
ging problem and applied naive Bayes and decision
tree to it. Their ... system performs much better
than both (Blaheta and Charniak, 2000) and (Lin-
tean and Rus, 2007a). For two major categories,
namely grammatical and form/function which ac...
Báo cáo khoa học: "Investigations on Word Senses and Word Usages" ppt
... Goodenough, 1965; Miller and Charles,
1991), and human judgments have previously been
used successfully to study synonymy and near-
synonymy (Miller and Charles, 1991; Bybee and
Eddington, 2006). ... Rosch and
Mervis, 1975), and there are borderline cases on
which people disagree more often, and on whose
categorization they are more likely to change their
minds (Hampton, 1979;...
Báo cáo khoa học: "Frequency Matters: Pitch Accents and Information Status" pptx
... of an accent’s shape
(van Santen and M
¨
obius, 2000)), c1 and c2 model
the ranges of the rising and falling amplitude of
the accent’s contour, respectively, and parameter d
expresses the peak ... given and new with pitch ac-
cent types L∗H and H∗L. The distributions show a clear
trend towards greater similarity form high-frequency “given
L∗H” and “new L∗H” to mid-frequency “new...
Báo cáo khoa học: The binding of foot-and-mouth disease virus leader proteinase to eIF4GI involves conserved ionic interactions ppt
... and therefore is independ-
ent of the interaction between eIF4E and eIF4G
[10,11]. The picornaviral proteinases such as the leader
proteinase (L
pro
) of foot -and- mouth -disease virus
(FMDV) and ... (eIF4GI) and I4G3_human
(eIF4GII). (B) Comparison of the C-terminal
extensions of FMDV Lb
pro
, ERAV Lb
pro
and
ERBV Lb
pro
. Asterisks in (A) and (B) indicate
conserved basic resid...
Báo cáo khoa học: Genomic structure, promoter analysis and functional mutation pptx
... the G264V homozygote, and 195
and 227 pgÆmL
)1
in the control subjects. Concentration of plasma
glycerol at time 0 w as 104.4 lmol ÆL
)1
in the G264V hom ozygote, and
55.7 and 97.2 lmolÆL
)1
in ... V59L and G264V), and two silent mutations
(A103A and G250G). The cRNA injection of the missense
mutants into Xenopus oocytes revealed the a bsence of the
activity to transport glycero...
Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
... sig-
nalling [3–5] and of cytokines such as interleukin (IL)-6
[6]. It is also involved in transformation and tumour
progression [7] and its activation, as detected in breast,
head and neck, lung and colon ... control ODN (con) and the dead cells were counted after 16, 24 and 48 h of culture using trypan blue staining. (C) Cells were
treated with 0.5, 1 and 2 lg of hpST3dODN...
Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt
... diagnostic and therapeutic schemes.
Antisense-RNA, ribozyme, aptamer and siRNA tech-
nologies have been developed and have found applica-
tion in molecular medicine [1–7]. Signalling aptamers
and aptazymes ... as three additional
bands (lanes 3 and 4). These signals correspond to the
29- and 35-mer resulting from ligation of the 20-mer
to either the 9- or 15-mer cleavage product,...