Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... 2002 Binding of apolipoprotein E3 and E4 to emulsions (Eur. J. Biochem. 269) 5949 Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions Matthew ... that apoE3 and apoE4 bind preferentially to small and large lipid particles, respectively. Direct binding analysis of ApoE3 and ApoE4...
Ngày tải lên: 08/03/2014, 09:20
Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... 4-diphosphocytidyl-2C-methyl- D- erythritol synthase, 4-diphosphocytidyl-2C-methyl- D-erythritol kinase and 2C-methyl- D-erythritol 2,4-cyclodiphosphate synthase [24–26] (Fig. 1). In the meantime, some of ... analyzed by HPLC in order to monitor the conversion of [1- 3 H]2C-methyl-D-erythritol 4-phosphate into the corresponding 2,4-cyclodiphosphate. The organic phase was a...
Ngày tải lên: 22/02/2014, 07:20
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... complex of the respiratory chains of mitochondria and many bacteria [1–4]. It catalyzes the reduction of oxygen to water, coupling the free energy of this reaction to the generation of a proton gradient ... set of mutants in surface-exposed residues to further identify amino acid side chains involved in the docking of cytochrome c, or in the presumed el...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
... 66.83 per 1000 informative offspring in the 1980s and within this, the total rate of major congenital abnormalities was 27.01 per 1000 informative offspring [1,2]. The causes of congenital ... the spectrum of congenital abnormalities evaluated, the period of study (only at birth or in early neonatal period or prenatal or the whole infant period are included), t...
Ngày tải lên: 02/11/2012, 11:12
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... environ- ment of tryptophan residues is essentially conserved in the mutant enzyme. On the other hand, the absence of major differences in the CD spectra of the wild-type and D153N agmatinases indicates ... connecting amino acids at the beginning and the end, were mutated to glycines and, after remodelling back to their side chains in agma- tinase, the w...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo khoa học: "Search in the Lost Sense of “Query”: Question Formulation in Web Search Queries and its Temporal Change" pptx
... questions to ex- press their search intent. 1 Introduction A web search query is the text users enter into the search box of a search engine to describe their infor- mation need. By dictionary definition, ... largely lost the orig- inal semantics of the word query: they tend to be fragmented phrases (“banana calories”) instead of questions. This could be a result of users...
Ngày tải lên: 17/03/2014, 00:20
Báo cáo khoa học: Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa potx
... photoactivation. Both the stability of the mutants and their ability to activate Gt could be correlated with the increase in size of the side-chain at position 51, pointing to a disruption of the interhelical ... (1996) Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinit...
Ngày tải lên: 22/03/2014, 16:20
Báo cáo khoa học: A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P3 and PtdIns(3,5)P2 pptx
... 7. An amino-terminal polybasic region is necessary for specific binding of PCaP1 to the phosphatidylinositol moiety. (A) The capacity of binding of PCaP1 to PtdInsP s (abbreviations as in Fig. ... PCaP1 tightly binds to the plasma membrane via N-myristoy- lation at Gly2 and specifically interacts with PtdIns(3,5)P 2 and PtdIns(3,4,5)P 3 in the membrane. N-myris...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo Y học: Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion pptx
... protein modeling Fig. 1. pS c urves for the hydrolysis of butyryl- thiocholine c atalyzed by the w ild-type, by v ar- ious human butyrylcholinesterase mutants and by horse butyrylcholinesterase in ... BuChEs. Two amino-acid residues (D70 and Y3 32) in the PAS and two (W82 and A328) in the CS, known to play a role in the binding of positively charged ligand...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101) A high-pressure stopped-flow study pdf
... its keto group and the hydroxyl group of the amino-acid residue Tyr-96, and (b) by hydrophobic contacts of its methyl groups C-8, C-9 to Val295 and Asp297 in the b 3 sheet, and of the methyl group ... iron ligand is a good probe for the polarity and therefore for the presence of water molecules in the heme environment of cytochrome P450cam. To get a f...
Ngày tải lên: 08/03/2014, 23:20