Báo cáo Y học: Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases ppt
Báo cáo Y học: Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases ppt
... intrinsic rotor channels. The common membrane embedded location of the binding site of ATP synthases suggest a common mechanism for ion transfer across the membrane. Keywords: coupling ion binding ... with cGlu65 of the ATP synthase of I. tartaricus or cAsp61 of the ATP synthase of E. coli and is therefore suitable for fluorescence investigations....
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"
... behavioral hypersensitivity (3-5). A cur- rent theory for the etiology of neuropathic pain in- volves CNS immune activation with cytokine pro- duction inducing the expression of final common pain ... administered intrathecally once daily for 7 days, starting from 1 day before CCI surgery. Evaluation of tactile allodynia and thermal hyperalgesia The paw withdrawal latency (PWL)...
Ngày tải lên: 25/10/2012, 11:48
Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... pre- existing amorphous amylopectin into the formation of B-type crystals. Another mechanism would consist of crystallization of newly synthesized molecules into B-type material. This could involve only de ... type of crystals synthesized under these conditions show that GBSSI induces the formation of B-type crystals either in close association with pre-existing amorphous amylop...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: A chimeric scorpion a-toxin displays de novo electrophysiological properties similar to those of a-like toxins docx
... quinquestriatus hebraeus scorpions [15]. Classically, binding of scorpion a-toxins to the receptor site 3 on the extracellular surface of sodium channels induces prolongation of action potentials due ... show any effect neither on action potential or sodium current decay as compared to BotXIV (data not shown). These data confirm the absence of insect toxicity noticed prev...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf
... function of AR.NTD. Alternative explanations might be induction of a more favorable NTD conformation or stabilization of the in vivo N/C interaction, which are not reflected in the pull-down assays and ... Together with coactivators, general transcription factors and RNA polymerase II, they form a stable transcription initiation complex [1–4]. Upon ligand binding, the LBD acquir...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx
... and the stereoselectivity of the reduction deter- mines the direction of synthesis of these two 6-deoxyhex- oses. However, neither the gene encoding the biosynthesis of GDP-6-deoxy- D -talose nor ... respectively) to the proteins enco- ded by ORFs in the clusters responsible for synthesizing the SPAs in other serotypes of A. actinomycetemcomitans. The biosynthetic...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt
... probability of the receptor channels are the luminal Ca 2+ concentration in the endoplasmic reticulum [9,10], modulation or oxidation of the receptor sulfhydryl groups [11–14], and phosphorylation b y ... Heemskerk 1 1 Departments of Biochemistry and Human Biology, University of Maastricht, the Netherlands; 2 Department of Medical Physiology, University Medical Centre...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... stability of HT c-552, and the corresponding regions in the wild-type PA c-551 and its quintuple mutant. The mutated residues in the quintuple mutant, and the corresponding ones of the wild-type ... information on the mech- anism underlying protein stability. BIOGENESIS OF BACTERIAL CYTOCHROMES c To confirm experimentally the amino-acid residues respon- sible for the...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Iraqi health system in kurdistan region: medical professionals’ perspectives on challenges and priorities for improvement"
... professionals’ rating of the quality of services and availability of resources in the health institutions, their view on different aspects of the health system, and finally identifying the priority ... profes- sionals in clinical practice. The questionnaire was directly dispatched to the selected sample with a brief description of the purpose of the study, clarif...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"
... substitution of isoleucine 181 for methionine, as occurs in B19 genotype II, results in the reduction of B19 NS1-induced cytotoxicity of liver cells. Our results support the hypothesis that in the ... po- tential orientation of the side chain and hence a change in the secondary structure of that region in the protein. Since the I181M substitution did not oblite- ra...
Ngày tải lên: 26/10/2012, 09:32