Báo cáo khoa học: Anti-HIV-1 activity of 3-deaza-adenosine analogs Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners pot
Báo cáo khoa học: "Brutus: A Semantic Role Labeling System Incorporating CCG, CFG, and Dependency Features" pot
... terms of the combinatory potential of the lexical (word-level) items. Rather than using standard part -of- speech tags and grammatical rules, CCG en- codes much of the combinatory potential of each ... classes of local and long- range (including unbounded) dependencies. CFG- based approaches often rely on examining potentially long sequences of categories (or treepaths) betwee...
Ngày tải lên: 17/03/2014, 01:20
Báo cáo khoa học: " A simple pattern-matching algorithm for recovering empty nodes and their antecedents∗" pot
... corpora: (i) a version of section 23 of the Penn Treebank from which empty nodes, indices and unary branching chains consisting of nodes of the same category were removed, and (ii) the trees produced ... consists of the triple of cat- egory plus string positions as above, together with the set of triples of all of the non-empty nodes the empty node is co-indexed with. (U...
Ngày tải lên: 17/03/2014, 08:20
Báo cáo khoa học: Something from nothing ) bridging the gap between constraint-based and kinetic modelling pot
... School of Mathematics, The University of Manchester, UK 3 School of Chemical Engineering and Analytical Science, The University of Manchester, UK 4 School of Chemistry, The University of Manchester, ... emergent field of systems biology involves the study of the interactions between the components of a biological system, and how these interactions give rise to the functio...
Ngày tải lên: 23/03/2014, 07:20
Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... PAGE (15% gel) and analyzed by WB with mAb against GFP to detect proteolysed fragments of mGFP–calpain 7–Strep. Bands of full-length WT and C290S are indicated by the arrow, and those of 30 K are ... volume of a vehicle used for dissolving reagents was added to the reaction mixture in place of inhibitors. Bands of full- length mGFP–calpain 7–Strep and those of 30 K are s...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: ATPase activity of magnesium chelatase subunit I is required to maintain subunit D in vivo ppt
... done by facilitating protein folding and unfolding, assembly and disassembly of protein complexes, degradation of protein, replication and tran- scription of DNA, etc. [11–13]. Here we found that ... identification of a Chl D cDNA sequence encoding a third subunit, analysis of the interaction of the three subunits with the yeast two-hybrid system, and recon- stitution of...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Structure-activity relationships of a-conotoxins targeting neuronal nicotinic acetylcholine receptors ppt
... specificity and potency, A10 and N11, are shown in pink and labeled. Residues 4–7 and 9–10 in the closely related PnIB have also been shown to influ- ence activity [38]. Ó FEBS 2004 Structures of neuronally ... feature of an arginine residue at position 12 (Table 1) appears to contribute to a4b2anda7 subtype activity but not a3b2 activity. A decrease in a4b2 and a7 subtype a...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx
... the mechanism of action of chymotrypsin: the role of the low barrier hydrogen bond. Biochemistry 36, 4576–4584. 46. Warshel, A. (1998) Electrostatic origin of the catalytic power of enzymes and the role of ... interested in the molecular basis of substrate activation in wild-type and mutants of human BuChE [11,15,16], as well as substrate activation in wild-type and muta...
Ngày tải lên: 20/02/2014, 23:20
Tài liệu Báo cáo khoa học: Endotoxic activity and chemical structure of lipopolysaccharides from Chlamydia trachomatis serotypes E and L2 and Chlamydophila psittaci 6BC pdf
... C. trachomatis sero- type E and L 2 were of similar activity and both less active than smooth LPS by a factor of 100 whereas, LPS from Chl. psittaci was of lower activity than the two other chlamydial ... well known that LPS of Gram-negative bacteria in general is one of the most potent stimulators of innate immunity and that the lipid A moiety of LPS is responsible fo...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: The N-terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+-dependent activity pot
... purified and biochemically characterized. Tma-RNase HI prefers Mg 2+ to Mn 2+ for activity, and specifically loses most of the Mg 2+ -depen- dent activity on removal of the HBD and 87% of it by ... presence of 1mm MgCl 2 and MnCl 2 were 410-fold lower and 1.6-fold higher than those of Tma-RNase HI. The K m values of Tma-CD determined in the presence of 1 mm MgCl 2 an...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction ppt
... field and a combination of Simplex [65] and Powell algorithms [66]. Coordinates of the NMR structures of the BIR2 [49] and BIR3 [50] domains were achieved from the Protein Data Bank files: 1C9Q and ... of a high level of apoptotic activation and the upregulation of IAPs in tumor tis- sue [8,16]. Inactivation of XIAP or the cancellation of XIAP inhibition appears both...
Ngày tải lên: 07/03/2014, 12:20