Báo cáo khoa học: Isocitrate dehydrogenase of Plasmodium falciparum Energy metabolism or redox control? doc

... interacting factors could modify the molecular phenotypic effect of using this vector. This is the first report of the detection at the molecular level of the toxic effect of a DNA vector in P. falciparum. Although ... [43,44]. An important role of thioredoxin is to reduce ribonucleotide reductase. P. falciparum TrxR is able to reduce thioredoxin, which together with per- oxyredo...

Ngày tải lên: 19/02/2014, 07:20

... conferring traits of novel value or efficacy. Acknowledgements The work carried out in the laboratory of L. Pollegioni was supported by grants from Fondo di Ateneo per la Ricerca; he also thanks G. Molla for ... however, was devoid of substrate or inhibitor, and consequently did not reveal the nature of the active site or the mode of action of glyphosate. A dec- ade later, th...

Ngày tải lên: 14/02/2014, 14:20

... phylogenetic analysis of all of these sequences together with those of the more conventional lysozyme c type; the results suggested that these two lysozymes originate from a common gene ancestor, at least ... Complete genomes of a greater panel of species will be soon available. This will allow us to assess whether or not the lysozyme i gene has been lost from the origin of the...

Ngày tải lên: 19/02/2014, 12:20

... provide any sort of smoothing for the df i,j factor and is therefore susceptible to errors in corpora where a term occurs in docu- ments of only one or the other class and therefore df i,j = ... probabilistic model for information retrieval and is one of the most popular and effective algorithms used in in- formation retrieval. For ease of reference, we in- corporate the BM25 tf and...

Ngày tải lên: 20/02/2014, 04:20

... advantages of employ- ing deeper linguistic information have not been clarified yet. In this work, we pro- pose a novel approach for meta-evaluation of MT evaluation metrics, since correla- tion cofficient ... reliability of metrics when identifying wrong or high quality transla- tions, we look for contradictory results between the metric and the assessments. In other words, we look for...

Ngày tải lên: 20/02/2014, 07:20

... combination of CONNECTOR and SEPARATOR descriptions required For a closed window, while a somewhat different set Is required For an open window. These sets of descriptions form a small set of ... From memory this OF description of what it means For a bottle to be open. This information is stored Peneath its prototype For bottles. Presumably, there Is also script-like...

Ngày tải lên: 21/02/2014, 20:20

... constitutes a mi- nority of all instances of it. Evans (2001) reports that his corpus of approx. 370.000 words from the SUSANNE corpus and the BNC contains 3.171 examples of it, approx. 29% of which are ... part of the corpus. They report a final success rate of 92.2% on the test corpus. Nowadays, most current coreference resolution systems for written text include some means for...

Ngày tải lên: 22/02/2014, 02:20

... Molecular Biology Core, Sandler Center for Basic Research in Parasitic Diseases, University of California, San Francisco, CA, USA 4 Department of Pathology, Stanford University School of Medicine, ... of each of the four deoxynucleo- side triphosphates, Taq DNA ligase buffer, 5 U of Vent DNA polymerase and 5 U of Taq DNA ligase. After 35 cycles of PCR amplification (94 °C for 6...

Ngày tải lên: 07/03/2014, 03:20

... suppres- sion of the endogenous microflora and therefore may play an important role in the progression of the disease. The formation and tolerance of p-cresol by C. difficile as the end product of tyrosine ... C. difficile or recom- binant activating enzyme to a specific activity of 7 UÆmg )1 . Preliminary results suggest that phosphorylation of the small subunit is responsible for th...

Ngày tải lên: 07/03/2014, 15:20

... F1 for NER and Accuracy for NEN, suggesting the im- portance of external knowledge for this task. 5.5 Discussion One main error source for NER and NEN, which accounts for more than half of all ... Future work We study the task of NEN for tweets, a new genre of texts that are short and prone to noise. Two chal- lenges of this task are the dearth of information in a single tweet and...

Ngày tải lên: 07/03/2014, 18:20