Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
... Sensitivity to Hsp90- targeting drugs can arise with mutation
to the Hsp90 chaperone, cochaperones and plasma membrane
ATP binding cassette transporters of yeast
Peter W. Piper
1
, ... used yeast to
show that cells can be rendered hypersensitive to Hsp90
inhibitors by mutation to Hsp90 itself (within the Hsp82
isoform of yeast...
Báo cáo khoa học: Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin pptx
... 2008 The Authors Journal compilation ª 2008 FEBS
well with the extent of synaptic loss and severity of
cognitive impairment [3–9]. The higher cytotoxicity of
soluble Ab species compared with ... protein
folding in archaea, and is known to assist in the bio-
genesis of actins, tubulins and possibly other proteins
in the cytosol of eukaryotes [24]. Eukaryotic PFD...
Tài liệu Báo cáo khoa học: Parvalbumin deficiency in fast-twitch muscles leads to increased ‘slow-twitch type’ mitochondria, but does not affect the expression of fiber specific proteins doc
... of that order is found
for both COX isoforms, as well as for cytochrome c.
On the other hand, the up-regulation of F1-ATPase b
was clearly smaller and comparable to the composition
of SOL mitochondria, ... sufficient to induce the transcription of
genes encoding mitochondrial proteins. To test this
hypothesis, we determined the mRNA levels for
COX I, COX Vb and F1-A...
Tài liệu Báo cáo khoa học: Quantitative estimation of channeling from early glycolytic intermediates to CO2 in intact Escherichia coli pdf
... made in the
pathway dissociate from PGI and equilibrate with the
pool of Fru6P in the aqueous cytoplasm, then there
would be no channeling. When there is no channeling,
the result of the competition ... dissociated from
their enzymes and entered the cytosol. (In order to
facilitate uptake of intermediates these investigators
permeabilized the cells with dextran s...
Tài liệu Báo cáo khoa học: "Name Translation in Statistical Machine Translation Learning When to Transliterate" pptx
... deficiencies in the gold
standard, we achieve precision of 92.1% and recall
of 95.9% in the name tagging task.
5 Integration with SMT
We use the following method to integrate our
transliterator into the ... provides the
overall SMT system with up to 5 alternatives,
augmented with a choice of English translations
for the Arabic prefixes like the comma and the...
Tài liệu Báo cáo khoa học: Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing pdf
... attachment of DNA to the
enzyme. The yield of the photochemical cross-linking
reaction was calculated as the ratio of the covalent
conjugate radioactivity to the total radioactivity of the
conjugate and ... sequence
with oxoG in the middle in the lesion-bearing DNA strand
and specifically binds to it and the oxoG-pairing residue of
the other strand...
Báo cáo khoa học: Protein transport in organelles: Dual targeting of proteins to mitochondria and chloroplasts ppt
... understanding of the role of any cyto-
solic factors involved, and whether they play any regu-
latory role, would explain how each organelle obtains
the appropriate amount of protein. An understanding
of ... chloroplasts (Toc)64 and Toc159 system used
by proteins involved in photosynthesis [36]. The
Toc159 family in Arabidopsis consists of four proteins:
Toc159, Toc132, To...
Báo cáo khoa học: "Does Size Matter – How Much Data is Required to Train a REG Algorithm?" potx
... sin-
gling out the target from the other objects in the
scene (the distractors). Crucially, Dale and Reiter do
not specify how the ranking of attributes should be
determined. They refer to psycholinguistic ... started with five sets
of size 1, then added 4 items to each of them to cre-
ate five sets of size 5, etc. This resulted in five series
of increasingly sized t...
Báo cáo khoa học: "Who, What, When, Where, Why? Comparing Multiple Approaches to the Cross-Lingual 5W Task" pptx
... from
the parser to map parser constituents to the 5Ws.
First the Who, When, Where and Why were ex-
tracted, and then the remaining pieces of the sen-
tence were returned as the What. The goal ... decided to mark the When, Where
and Why answers Incorrect by default. We added
clarifications to the guidelines and discussed ar-
eas of confusion, and then...
Báo cáo khoa học: " Thumbs Up or Thumbs Down? Semantic Orientation Applied to Unsupervised Classification of Reviews" doc
... The difficulty with movie
reviews is that there are two aspects to a movie, the
events and actors in the movie (the elements of the
movie), and the style and art of the movie (the
movie as ... searches.
The third step is to calculate the average seman-
tic orientation of the phrases in the given review
and classify the review as recommended if...