Báo cáo khoa học: Death inducer obliterator protein 1 in the

Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx

... HYPOTHESIS Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role Ana M. Rojas 1, 2 , Luis Sanchez-Pulido 1 , ... noteworthy that the retrieved proteins all appear to have a role in DNA regulation, in the context of chromatin stability, and...

Ngày tải lên : 07/03/2014, 21:20

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Báo cáo khoa học: Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer potx

... nm. When MBP–apoptin-IA was combined with MBP– apoptin-FM in NaCl/P i ata10:1molarratioof incorporated label and incubated at 30 °C, we observed a clear increase in F FM /F IA over the course of 24 ... IA and FM and combined at the same label ratio. (B) IA ﬁ FM FRET- based exchange assay. MBP–apoptin-IA and MBP–apoptin-FM were combined at an IA to FM ratio of 10 : 1 and inc...

Ngày tải lên : 23/03/2014, 21:20

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Báo cáo khoa học: Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases ppt

... simultaneously into the catalytic centre of the A domain awaiting amino acyl transfer. To adopt this conformation, the PCP domain has to dock on the A domain in an orientation whereby the Ppant attachment ... domains of the tyrocidine and bacitracin NRPS. Cys3 31 is part of the binding pocket of the amino acid in the active site [11 ]. The mutation Cys...

Ngày tải lên : 29/03/2014, 08:20

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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... in various organ systems. Even in organisms lacking a brain, such as Caenorhabditis elegans, the nervous system plays a key role in maintaining energy balance [1 4]. In more advanced, mammalian ... synthase activates PPARalpha to maintain energy homeostasis. J Clin Invest 11 7, 2539–2552. 19 Hu Z, Cha SH, Chohnan S & Lane MD (2003) Hypo- thalamic malonyl-CoA as a med...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: "Toward finer-grained sentiment identification in product reviews through linguistic and ontological analyses" ppt

... level of detail. If the customer wants to comment on some attributes in detail, she could use a fine- grained concept (e.g., the width of the thigh part of the pants) rather than a coarse-grained ... manually. We obtained raw text reviews from one of the major online shopping malls in Korea 1 and per- formed a morphology analysis and POS-tagging. After POS...

Ngày tải lên : 20/02/2014, 09:20

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Tài liệu Báo cáo khoa học: "Subgrammars, Rule Classes and Control in the Rosetta Translation System" ppt

... One of its 12 1 disadvantages is that it leads to a proliferation of rather unnatural categories. It is hard to find an elegant and transparent way of specifying rule order in a compositional ... individual grammars may be com- plicated because of the attuning. • Principle of Interllnguality: There is an intermediate language into which analysis com- ponents of...

Ngày tải lên : 22/02/2014, 10:20

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Báo cáo khoa học: Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus ppt

... expansion in ataxin-3 is the cause of the most common dominant ataxia, spinocerebellar ataxia type 3 (SCA3, also known as Machado–Joseph disease). SCA2, SCA6, SCA7 and SCA17 are also caused by ... that of the rapidly exchanging inclusions. Inverse FRAP analysis of ataxin- 1 indicated that wild-type ataxin -1 shuttles between the nucleus and the cytosol, whereas polyQ-expa...

Ngày tải lên : 06/03/2014, 09:22

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Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx

... small-interfering RNA abolished insulin-induced heme oxygenase -1 induction. Insulin was also found to acti- vate the mitogen-activated protein kinase cascades p38 and extracellular signal-related ... Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway. FEBS Lett 512 , 15 7 16 2. 53 Fukuda...

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: "Parsing Free Word Order Languages in the Paninian Framework" pptx

... (19 76), (19 88)). See Fig. 1. Two of the important karakas are karta karaka and karma karaka. Frequently, the karta karaka maps to agent theta role, and the karma to theme or goal theta role. ... karaka of 'le' (take) is the karana (instru- mental) karaka of 'kAta' (cut). G.I rAma Pala KAkara mohana ko bulAtA hE. Ram fruit having-eaten Mohan...

Ngày tải lên : 08/03/2014, 07:20

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Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf

... refraction [1 3]. Thermodynamic stability for crystallins is essential in maintaining lens transparency [4]. Determining the mechanism of folding and assembly of these proteins is important for ... disturbance Fig. 6. Diagram of the surface of duck d-crystallin (1AUWÆpdb). (A) Each subunit of the tetrameric d-crystallin shows a surface with several convex and concave areas...

Ngày tải lên : 08/03/2014, 08:20

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