Báo cáo khoa học: Oligosaccharide synthesis in Fibrobacter succinogenes S85 and its modulation by the substrate potx

... view independ- ence. The joining was performed under the condi- tion that the words in the two newsgroups in the first column came from one vocabulary, while the words in the newsgroups in the ... bilingual bootstrapping. In this paper, we propose the use of uncertainty reduction in the study of collaborative bootstrap- ping (both co-training and bilingua...

Ngày tải lên: 20/02/2014, 16:20

... hydrophobic interactions in proteins [26]. Removing a methyl group in the protein hydrophobic core affects protein folding and decreases the protein stability in mutant proteins [27]. In PR, two ... Exploring the changes in PR due to binding of two different inhibitors will give insight into the mechanisms of resistance and help in the design of new inhibitors. Resul...

Ngày tải lên: 18/02/2014, 04:20

... FEBS 369 Thermal unfolding transition in the absence and in the presence of the different ligands The in uence of ligand binding on the thermal stability of C-LytA was studied by monitoring the CD ... sigmoidal transitions (Fig. 2A), reflecting the presence of high- affinity and low-affinity binding sites in the protein and cooperativity in binding [20]. In con...

Ngày tải lên: 19/02/2014, 05:20

... an extracellular ligand-binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. The binding of a ligand to the extracel- lular domain of the EGFR induces receptor dimeriza- tion, ... are down-regulated by gefitinib or erlotinib in intestinal epithelial cells [53]. Furthermore, the expression of cIAP-1 and of X-linked IAP is reduced by AG1478 in s...

Ngày tải lên: 16/02/2014, 09:20

... protein involved in the coordination of cell wall synthesis and cell growth [18], the nucleoprotein and phosphoprotein from measles and Sendai viruses [19,20] and the Rhabdoviridae phosphoprotein ... (2008) Mapping alpha-helical induced folding within the intrinsically dis- ordered C-terminal domain of the measles virus nucleo- protein by site-directed spin-labeling EP...

Ngày tải lên: 18/02/2014, 04:20

... inhibi- tion of the b-catenin signaling pathway by quercetin prevented increases in lung fibroblast proliferation and collagen synthesis induced by a-defensin-1 and a-de- fensin-2. Furthermore, by using a ... proliferation and collagen synthesis involve the b-catenin signaling pathway. Inhibition of b-catenin signaling pathway using quercetin blocked the a-defensin-indu...

Ngày tải lên: 18/02/2014, 06:20

... VEGF expression and induced angiopoietin-1 (Ang-1), thereby promoting the expression of tight junction proteins and strengthening the bonds between brain endothelial cells [19]. Recent studies indicate ... brain damage, microglia begin to modify their behavior and acquire an ameboid form. This, in turn, alters their antigen presentation and stimulates the release of cytokines,...

Ngày tải lên: 18/02/2014, 11:20

... organs, including the brain, is regulated by the VEGF system in combination with other signaling systems such as the angiopoietin–Tie, ephrin–Eph, Delta–Notch sys- tems, and the Wnt pathway. Furthermore, ... astrocytes, and the tight junctions of vascular endothelial cells (ECs) in the BBB are well organized with claudins and ZO- proteins through a decrease in angiog...

Ngày tải lên: 18/02/2014, 11:20

... reinter- preted in the context of angiogenesis in the brain. Is it possible that some of the acute neurovascular events in the brain after stroke represent an endogenous attempt by the brain ... signaling actions involving the platelet-derived growth factor and low-density lipo- protein receptors [32,33]. These experimental findings are now beginning to be supported by...

Ngày tải lên: 18/02/2014, 11:20

... EIIA, B and C domains, with the EIIA and B do- mains being part of the phosphorylation chain and the EIIC domain representing the membrane domain. As all components of the PTS, depending on their ... modules. The pathways for the individual carbohydrates, including the description of protein synthesis, are connected to the glycolysis module. The PTS reactions, the...

Ngày tải lên: 18/02/2014, 13:20