Báo cáo khoa học: Factors affecting habituation of PC12 cells to ATP potx

... ATP leads to habituation of the secretory r esponse. In this paper, we use amperometric detection to monitor the habituation of PC12 cells to mul- tiple s timulations of ATP or its agonist. Cells ... been normalized to the response of PC12 cells to 300 l M ATP under control conditions. The scaled response of PC12 cells to ATP and 2MeSATP in the...

Ngày tải lên: 07/03/2014, 16:20

... represented by n variables (within-subjects factors) . Categorical factors are used to divide study popula- tion into subgroups (between-subjects factors) and continuous variables are used as ... CYP3A5 prior to transplantation im- proves the individualization of immunosuppressive therapy although epigenetic factors must be taken into account [7]. The aim of the present stu...

Ngày tải lên: 26/10/2012, 09:32

... mg of [2- 13 C 1 ]- or [3- 13 C 1 ]glucose, 3.5 mg of phosphoenol pyruvate, 0.5 mg of ATP, 6 mg of 2-oxoglutaric acid, 0.6 mg of NAD + , 2.5 mg of NH 4 Cl, 5mgofa 13 C-isotopologue mixture of ... transfor- mation of these isotopologue libraries into random libraries of 13 C isotopologues of FMN and their utili- zation for NMR studies of the plant blue light recep- tor,...

Ngày tải lên: 07/03/2014, 05:20

... transiently stored and rerouted to polysomes to be translated [17]. P-bodies are highly mobile within the cytoplasm, intermittently attaching to stress granules [14]. Factors such as the cytoplasmic ... induction of stress gran- ules. To determine the domain(s) responsible for induction and ⁄ or recruitment of Roquin to stress gran- ules, we took advantage of the observation...

Ngày tải lên: 15/03/2014, 11:20

... Unit, Laboratory of Physiology, School of Medicine, University of Ioannina, Greece 2 Laboratory of General Biology, School of Medicine, University of Ioannina, Greece 3 Laboratory of Cellular ... induced apoptosis of human tumor epithelial cells [21]. Accumulation of nCLU correlated with inhibition of cell proliferation and induction of apoptosis of human tumor epith...

Ngày tải lên: 16/03/2014, 02:20

... fractionation or reverse-phase chromatography were analysed by MALDI-TOF and subjected to exo- or endoglycosidase digestions. MALDI-TOF MS analysis MALDI-TOF MS was carried out as described previously [24]. ... Some of them are commercially available and widely used as tools in glycomic research. The majority of these enzymes seem to be part of the degrada- tion and recycling proces...

Ngày tải lên: 16/03/2014, 16:20

... vivo assessment of toxicity and pharmacokinetics of methylglyoxal – augmentation of the curative effect of methylglyoxal on cancer-bear- ing mice by ascorbic acid and creatine. Toxicol Appl Pharmacol ... d-lactate. Restoration of a functional glyoxalase system by expression of T. cruzi GLO1 in T. brucei resulted in increased resistance to methylglyoxal and increased conversion...

Ngày tải lên: 23/03/2014, 06:20

... useful to be able to predict the likely interactions of an inhibitor designed to target one particular kinase with other kinases. It is generally assumed that the mode of binding of an inhibitor to ... shift towards the exit of the cavity, the nonpolar contacts from CK2 to TBB are slightly more numerous (73 contacts) than those of CDK2 to TBB (52 contacts). The closer fit...

Ngày tải lên: 23/03/2014, 21:20

... belonging to the class; Exact Pred, number of predictions (out of a total of 14) corresponding to annotations found in UniProt, Entrez Gene and InterPro databases; Exact GOFN, number of predicted GOF ... contacting the predictors. Each method was assigned to one or more of five categories (F1 to F5), here called features, on the basis of the type of information used by pr...

Ngày tải lên: 30/03/2014, 10:20

... known to be an important effector of the dynamics in yeast extracts [37]. Autocatalytic stoichiometry of ATP The stoichiometry of glycolysis makes the pathway autocatalytic in ATP, as two moles of ... to the actual drip of the drop. In the case of yeast extracts, we will show below that the slow time-scale corres- ponds to removal of the allosteric phosphofructo- kinase...

Ngày tải lên: 30/03/2014, 16:20