Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt
Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt
... Neuroserpin Portland (Ser52Arg) is trapped as an inactive
intermediate that rapidly forms polymers
Implications for the epilepsy seen in the dementia FENIB
Didier Belorgey
1
, ... neuroserpin was comparable to that obtained for
other serpins, including a
1
-antitrypsin and a
1
-antichymo-
trypsin [19,20]. In comparison, the spectrum of S...
Báo cáo khoa học: Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii Implications for the disulfide metabolism of anaerobic hyperthermophiles doc
... there is a blue shift in the 380 nm
peak and subsequent small increase in absorbance at
340 nm, although the increase is much less than that
expected for the amount of NADPH added (the
increase ... nm
and 400 and 500 nm. There is also an increase and
blue shift in the peak which corresponds to the 380
and 360 nm peaks of the E and EH
2
forms, respect-
ively. Th...
Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
... 68% of the decrease in J
o
, 68% of the
decrease in J
p
, 56% of the increase in the QH
2
⁄ Q
ratio, 70% of the increase in Dw, 72% of the increase
in the ATP
in
⁄ ADP
in
ratio, and 59% of the decrease ... were determined from yeast hexo-
kinase kinetics as described [16]. As hexokinase kinetics
were determined in medium containing creatine and creat-
ine p...
Báo cáo khoa học: Purification, microsequencing and cloning of spinach ATP-dependent phosphofructokinase link sequence and function for the plant enzyme pdf
... microsequencing and cloning of spinach
ATP-dependent phosphofructokinase link sequence and
function for the plant enzyme
Christian Winkler, Britta Delvos, William Martin and Katrin Henze
Institute ... reaction was initi-
ated by addition of 0.4 mmd-fructose 6-phosphate, and
activity was determined by decrease in absorbance at
340 nm. For discrimination between the chloroplast and cy...
Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx
... domain binding motif in their C-termini.
PDZ domains have been established as sites for protein–protein inter-
action and play a central role in organizing diverse cell signaling assem-
blies. In ... grouped into three
main classes of PDZ binding motifs, occurring at the
C-terminus of the interacting proteins [16]. We scanned
the human olfactory receptor repertoire for putat...
Tài liệu Báo cáo khoa học: Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain doc
... specific binding, the antisera were preincubated
with purified recombinant Cyp4x1 protein, resulting in
the ablation of detection of the 55-kDa protein in brain
(Fig. 5C). This shows that the antisera ... the
corresponding protein is translated in vivo. An antibody
specific for the mouse Cyp4x1 protein was developed,
as an antibody raised against human CYP4x1 showed...
Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... thus
excluding any interchange of subunits. Nevertheless, it was
apparent that the fluorescence intensity of the ac bands in
all reoxidized samples was rather weak, a lthough the SDS
band was very intense. ... cA285C was
generated by standard PCR with pKH7 as template DNA
and using KpnIandSacI for transferring the PCR product
into pKH7 (resulting in plasmid pMM9). The mutat...
Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx
... involved in the synthesis of
fatty acids in plastids, including the stearoyl acyl carrier
protein desaturase SSI2, and the plastidic long-chain
acyl-CoA synthetase LACS9 (for a complete list of
co-expressed ... forma-
tion by introducing the oxygen between carbon 9 and 10
of oleic acid before incorporation of the monomer into
the cutin. In this context, it is interesting...
Báo cáo khoa học: VEGF gene expression is regulated post-transcriptionally in macrophages pdf
... coordinately regulated.
Experimental procedures
Cell culture, transfection and luciferase assay
The RAW-264.7 cell line was obtained from ATCC
(Manassas, VA) and maintained as described. Media was
DMEM ... underlined) in mouse is nonhomologous to human
(human U-358, GenBank #AF024710). Following muta-
genesis, the sequence of the VEGF-dL-luc was verified by
sequencing on both stran...
Báo cáo khóa học: ICAM-1 expression is highly NF-jB-dependent in A549 cells No role for ERK and p38 MAPK docx
... molecules as well as other enzymes, such as
inducible nitric oxide synthase and cyclooxengenase-2,
NF-jB may provide an attractive target for therapeutic
intervention in inflammatory diseases [2]. ... agents that trigger exacerbation in airway
diseases [15]. This epithelium is biosynthetically active and
acts as a source of multiple in ammatory cytokines,
chemokines, prost...