Báo cáo khoa học: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives pdf

Báo cáo khoa học: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives pdf

Báo cáo khoa học: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives pdf

... 2673–2683 ª 2006 The Authors Journal compilation ª 2006 FEBS 2683 Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives Elena J. Rossi 1,2, *, Lyann Sim 1,2, *, Douglas ... miglitol (2), salacinol (3) and kotalanol (4); (5–7) are derivatives of salacinol with substi- tutions in the ring. (8–9) are ring expanded salacinol derivatives...

Ngày tải lên: 07/03/2014, 12:20

11 527 0
Tài liệu Báo cáo khoa học: Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack docx

Tài liệu Báo cáo khoa học: Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack docx

... inactivation of G APDH being metal- ion independent, whereas inhibition of GR and LDH by H 2 O 2 occurs most rapidly in the presence of metal ions. It is proposed that the inhibition of GAPDH and GR by these 1 O 2 -generated ... in its 1 D g state; 1 O 2 )is generated by a number of enzymatic and chemical reactions, by UV exposure, and by visible light in the p...

Ngày tải lên: 21/02/2014, 03:20

10 462 0
Tài liệu Báo cáo khoa học: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles pptx

Tài liệu Báo cáo khoa học: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles pptx

... reactions of trans-sulfura- tion through the production of homocysteine, biologi- cal methylations of DNA, lipids and proteins, and polyamine biosynthesis through the production of methionine and S-AdoMet ... result of this approach indicated the orienta- tion of 5-methyltetrahydrofolate in the MetS active site. Figure 5 shows the superimposed structures of DHPS and 5-me...

Ngày tải lên: 19/02/2014, 05:20

13 424 0
Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx

Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx

... The purity of these fractions was determined by measuring the activities of d-glucose phosphate phosphohydrolase and 5¢-ribonucleotide phosphohydrolase for the microsomal fraction and of cytochrome ... modulation by endogenous effectors, drugs and diesterasases. Phar- macol Rev 49, 1–51. 14 Ying WL, Emerson J, Clarke MJ & Sanadi DR (1991) Inhibition of mitochondrial ca...

Ngày tải lên: 16/03/2014, 22:20

12 428 0
Tài liệu Báo cáo khoa học: "Part-of-Speech Tagging for Twitter: Annotation, Features, and Experiments" pdf

Tài liệu Báo cáo khoa học: "Part-of-Speech Tagging for Twitter: Annotation, Features, and Experiments" pdf

... source of user-created content, and a flurry of recent research has aimed to under- stand and exploit these data (Ritter et al., 2010; Shar- ifi et al., 2010; Barbosa and Feng, 2010; Asur and Huberman, ... of our data and provides an appropriate level of linguistic detail, and (2) a feature set that captures Twitter-specific properties and exploits ex- isting resources such...

Ngày tải lên: 20/02/2014, 04:20

6 670 0
Báo cáo khoa học: ` Inhibition of human ether a go-go potassium channels by 2+ Ca ⁄calmodulin binding to the cytosolic N- and C-termini potx

Báo cáo khoa học: ` Inhibition of human ether a go-go potassium channels by 2+ Ca ⁄calmodulin binding to the cytosolic N- and C-termini potx

... domains reduced inhibition of the functional channels by Ca 2+ ⁄ CaM. Employment of CaM-EF-hand mutants showed that CaM binding to the N- and C-ter- minus are primarily dependent on EF-hand motifs 3 and ... in steps of 3) and C-terminal (amino-acids 480–962 in steps of 3 and amino-acids 645–895 in steps of 2) cytosolic domains of hEAG1. Binding of BODIPY FL-labeled h...

Ngày tải lên: 07/03/2014, 12:20

13 500 0
Báo cáo khóa học: Development of recombinant inhibitors specific to human kallikrein 2 using phage-display selected substrates docx

Báo cáo khóa học: Development of recombinant inhibitors specific to human kallikrein 2 using phage-display selected substrates docx

... purification by Bradford assay and normalized by densitometry of Coo- massie Blue-stained SDS/PAGE gels [19]. Inhibition assays and stoichiometry of inhibition The stoichiometry of inhibition (SI) ... ACTs purified in one step by affinity chromatography. The efficiency of the bacterial recombinant system to produce active ACT was proved by the stoichiometry of inhib...

Ngày tải lên: 30/03/2014, 13:20

7 374 0
Báo cáo khoa học: Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen docx

Báo cáo khoa học: Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen docx

... Gulino 2 and Andrew R. Mackay 1 1 Section of Molecular Pathology, Department of Experimental Medicine, University of L’Aquila, Italy; 2 Department of Experimental Medicine and Pathology, University of ... regulation of cellular fibrinolytic activity and in the down-regulation of tumour-associated angiogenesis [31–38]. Human breast tumours exhibit some of these anomalies...

Ngày tải lên: 31/03/2014, 09:20

8 320 0
Tài liệu Báo cáo khoa học: Inhibition of pneumococcal choline-binding proteins and cell growth by esters of bicyclic amines pptx

Tài liệu Báo cáo khoa học: Inhibition of pneumococcal choline-binding proteins and cell growth by esters of bicyclic amines pptx

... analysis of ligand binding to C-LytA. (A) Con- formational changes induced by ligands on C-LytA monitored by near-UV CD with no ligand added (—) and upon addition of ligands: s, d, 2.5 and 20 m M ... cuvette and a protein concentration of 19 lm. Tryptophan emission spectra were obtained using an excitation wavelength of 280 nm, with excitation and emission slits of 3 nm,...

Ngày tải lên: 19/02/2014, 05:20

13 465 0
Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

... The importance of the L1 loop for DNA binding by RecA ⁄ Rad51 family proteins was observed by mutational and photocrosslinking analyses of RecA [34–37] and a mutational analysis of HsDmc1 [22]. The ... binding by bacterial single stranded DNA-binding protein (SSB) and human replication protein A (RPA) [23,24], we performed mutational analyses on Tyr232 in the L1 loop and...

Ngày tải lên: 19/02/2014, 06:20

12 662 0
w