Báo cáo khoa học: Endothelial signalling events during leukocyte transmigration pptx

... MINIREVIEW Endothelial signalling events during leukocyte transmigration Peter L. Hordijk Department of Molecular Cell Biology, Sanquin ... it takes two to tango is certainly true for leukocyte trans- endothelial migration. A growing pallet of leukocyte adhesion-induced signaling events in endothelial cells have been identified, mediating ... our current knowledge on the...

Ngày tải lên: 07/03/2014, 12:20

... manipulations are not [11,12,45]. Outstanding questions in NAADP signalling pathways There are still several important aspects of the NAADP signalling pathway that are unclear. Foremost is the nature ... been of great interest to investigate the physiology, enzymology and pharmacology of the NAADP signalling pathway. Recent reports have shown increases in NAADP levels in response to cel...

Ngày tải lên: 20/02/2014, 01:20

... is both necessary and sufficient. It is interesting that the two 12 kDa fragments that accumulate during proteolysis of the aggregate encompass the whole of domain C (starting at Leu292) plus an 4130 ... of aggregates and appears to be the nucleus of aggregation. As well as shedding light on the specific events associated with the aggregation of SK, this study provides insight into the natu...

Ngày tải lên: 21/02/2014, 03:20

... regulating anti-apoptotic signalling. ER ⁄ Golgi signalling Studies of ER ⁄ Golgi signalling provide some of the best evidence for isoform- and compartment-specific Ras signalling having phenotypic ... interesting to see whether endosomal Ras can also activate this signalling complex. Endosomal signalling The initiation points of most signalling cascades are the cell-surface loca...

Ngày tải lên: 07/03/2014, 00:20

... in sugar signalling are still largely unknown, but mutant screens have revealed a tight interaction with various hormone signalling pathways [2]. Glucose controls abscisic acid (ABA) signalling ... gene expression [41] and HXK-dependent signalling inter- acts positively and negatively with auxin and cytoki- nin signalling, respectively [19]. Glucose and ethylene signalling converge...

Ngày tải lên: 15/03/2014, 11:20

... Early signaling events induced by 280-nm UV irradiation Yukihito Kabuyama 1 , Miwako K. Homma 1 , Tomohiro Kurosaki 2 and ... eects on biological systems. To better understand the eects of UV in this range, early signaling events induced by monochro- matic UV light were investigated using the ch icken B cell line DT40 ... control DNA repair, DNA synthesis, transcription, and c ell cycle...

Ngày tải lên: 17/03/2014, 11:20

... Craig D, Sederoff RR, Clapham DH & von Arnold S (2004) Microarray analyses of gene expression during adventitious root development in Pinus contorta. Plant Physiol 135, 1526– 1539. 21 Himanen ... G, Bellin D, Pezzotti M & Delledonne M (2010) Characterization of transcriptional complexity during berry development in Vitis vinifera using RNA- Seq. Plant Physiol 152, 1787–1795. 33 Wi...

Ngày tải lên: 22/03/2014, 17:20

... the trade-off between adaptation 55 and preferences during content selection while Ex- periment II looks at this trade-off for modifier orderings during realization. Both studies use a novel interactive ... content planning has never been given, and neither have alignment effects in modi- fier orderings during realization been shown. With a few notable exceptions, such as Buschmeier et al...

Ngày tải lên: 23/03/2014, 16:20

... repression of cell prolifera- tion during megakaryocytic differentiation in K562 cells [21]. In addition, miR-34c is induced under the control of both p53 and p38-MAPK, and prevents Myc-dependent DNA replication ... the above- mentioned miRNAs are upregulated during GPC dif- ferentiation, which suggests that they might function in vivo by inhibiting Hh activity during the differentia- t...

Ngày tải lên: 14/02/2014, 19:20

Ngày tải lên: 19/02/2014, 19:20