Báo cáo khoa học: Selectins and glycosyltransferases in leuk

Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx

... protein kinase; MCF, macrophare chemotactic factor; MCIP, modulatory calcineurin-interact- ing protein; MDCK, Madin Darby canine kidney; MEF, mouse embryonic ﬁbroblast; MEK, MAP kinase/ERK kinase; ... accurately explain insulin-stimulated changes in the concentration of intracellular species and partitioning of glucose disposal in skeletal muscle. Insulin propagates a rather complex coo...

Ngày tải lên : 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc

... domain at their C-terminus, and a less conserved proline-rich and glutamine-rich transactiva- tion domain at their N-terminus [8–10]. Most isoforms also have a PY-motif (XPPXY) in the N-terminal ... speciﬁcally expressed in the central nervous system, retina, and developing heart [6]. AP-2e expression has been detected in the developing olfactory bulb, neural tissue, especially...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Molecular and cellular speciﬁcity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx

... (made in rat) and gp-anti-dW4 (produced in guinea pig), two antisera discriminating CHH isomers (gp-anti-pQl made in guinea pig and rb-anti- pQd in rabbit) [38] and an antiserum raised against ... arborizations containing D-Trp4 VIH (green) and D-Phe3 CHH (red). (H) Enlargement of axon terminals in the sinus gland with labelling as in (G). Peptidyl isomerization in neuro...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

... integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrins feeds into ... 5799 [7]. On the other hand, hyperosmotic shrinkage pre- vents insulin-induced hepatocyte swelling and proteo- lysis inhibition, indicating that swelling-dependent signaling essentially contri...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Molecular determinants of ligand speciﬁcity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc

... for screening and identifying ligand binding to protein receptors. Angewandte Chemie-International Edi- tion 42, 864–890. 16 Mayer M & Meyer B (1999) Characterization of ligand binding by saturation ... could indicate that the corre- sponding hydroxyl groups are involved in protein binding. The results for the linebroadening measurements of protons H1a in the alpha and beta conﬁgu...

Ngày tải lên : 18/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... Grb14 and IR proteins in liver subcellular fractions of control and insulin-injected rats. (A) Liver homogen- ates (H) prepared from ﬁve control ()ins) and ﬁve insulin-injected (+ins, 2 min postinjection) ... insulin signaling, and that it may repre- sent an interesting molecule with which to regulate liver insulin action. Experimental procedures Materials Porcine insulin, recombina...

Ngày tải lên : 18/02/2014, 18:20

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Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx

... N e -carboxymethyl-lysines and N e -carboxy- ethyl-lysines and pentosidine) being known to accumu- late with age on tissue proteins, and at an increased rate in LDL and atherosclerotic lesions in people with ... (1994) Binding and modiﬁcation of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with Nalpha-acetylarginine, Nalpha-acetylcy...

Ngày tải lên : 19/02/2014, 02:20

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Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... (1998) Anatomy of hot spots in protein interfaces. J Mol Biol 280, 1–9. 32 DeLano WL (2002) Unraveling hot spots in binding interfaces: progress and challenges. Curr Opin Struct Biol 12, 14–20. 33 ... antibodies contain six hypervariable regions in the variable (V) domains, three in the heavy chain V H and three in the light chain V L , that determine the complementa- rity with...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf

... according to published procedures [9,16,22], with some modiﬁca- tions. Total lysates were obtained by boiling 10 min in phosphate-buffered saline containing 0.5% SDS and 1.0% 2-mercaptoethanol, and ... formed in metabolically radiolabelled cells. The main radioactive oligosaccharides formed in BxPC3 cells (j in lower part, and A, B, and C of upper part) andT5ASclone(h in low...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx

... that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspecies interactions are incompatible. From ... -terminus are predicted to form a domain on the matrix side, and 36 form a domain extending into the intermembrane space. In the third mutant (V79-G35) one might expect a protein to be...

Ngày tải lên : 19/02/2014, 16:20

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Báo cáo khoa học: Selectins and glycosyltransferases in leukocyte rolling in vivo pdf

Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx

Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc