Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction ppt

... AFP antagonizes XIAP function FEBS Journal 273 (2006) 3837–3849 ª 2006 The Authors Journal compilation ª 2006 FEBS 3849 Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase ... Ac-Asp-Glu-Val-Asp-7-amino-4-methyl coumarin; AFP, a-fetoprotein; IAP, inhibitor of apoptosis protein; IBM, IAP-binding motif; RFU, relative fluorescence units; XIAP...

Ngày tải lên: 07/03/2014, 12:20

... kinase (JNK) and reactive oxygen species (ROS) on Tiam1 ⁄ Rac-induced upregulation of tissue inhibitor of metalloproteinase-1 (TIMP-1). (A) Effects of cat- alase and specific inhibitors of mitogen-activated ... Seiki M (1994) Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor...

Ngày tải lên: 19/02/2014, 05:20

... often overexpressed in solid and wet cancer types [10]. Muta- tions and amplification of the androgen receptor gene, without loss of gene expression, play a key role in the development of advanced, androgen-independent ... Swiss-Prot and similar databases. Structure and function of the linker histone variants Location and structure of the linker histones Historically, the l...

Ngày tải lên: 18/02/2014, 08:20

... subjects and by items in both the immediate naming and the delayed naming task. By-subjects and by-items (Ft and F2, respectively) analyses of variance were performed with grapheme frequency and ... grapheme detectors as a function of frequency of occurrence and differences in the strength of the connections between graphemes and phonemes as a function of assoc...

Ngày tải lên: 20/02/2014, 19:20

... upstream promoters of both HGAL and LMO2. PRDM1 binding suppresses endogenous protein and mRNA levels of HGAL and LMO2. In addition, promoter analysis reveals that site-specific binding of PRDM1 to the ... promoters is capable of repressing transcriptional activity. This inhibitory effect of PRDM1 suggests that it has a key role in the loss of HGAL and LMO2 expression u...

Ngày tải lên: 05/03/2014, 23:20

... property of amyloidogenic oligomers, at least in cell culture. Studies of the above-mentioned proteins and of other proteins linked to human amy- loidoses, including lysozyme [11] and prion protein [12], ... characterization of amyloidogenic protein states Mikael Lindgren 1 and Per Hammarstro ¨ m 2 1 Department of Physics, Norwegian University of Science and Technology...

Ngày tải lên: 06/03/2014, 09:22

... speed and brightness of DsRed variants. Protein Eng Des Sel 20, 525–534. 23 Verkhusha VV & Lukyanov KA (2004) The molecular properties and applications of Anthozoa fluorescent proteins and chromoproteins. ... Absorption, fluorescence excitation and emis- sion spectra of VFP and its variants. Fig. S3. pH dependence of the fluorescence of VFP and its variants in compari...

Ngày tải lên: 06/03/2014, 11:20

... subcellular localization and protein interactions of MPP3. We demonstrate the presence of MPP3 at the OLM and its interaction to MPP5. We demonstrate separate Mpp3 ⁄ Dlg1 and Mpp4 ⁄ Dlg1 complexes ... lanes 5 and 6) it was visible as a double band of 70 and 80 kDa, due to enrichment of the 80 kDa form [24]. The recombinant MPP5 has a molecular weight of 80 kDa. The in...

Ngày tải lên: 16/03/2014, 13:20

... delay time of 175 nsec and low mass gate at 800 Da. The mass spectra were externally calibrated with the molecular mass of a mixture of standard peptides. Results Comparison of ligand/Gb 3 binding ... GSLs, heterogeneity of fatty acid, and to a lesser extent, of sphingoid base, generates a spectrum of lipid isoforms of Gb 3 . Both the lipid structure [14–17] and the loca...

Ngày tải lên: 16/03/2014, 16:20

... sequence of observations x = x 1 , x 2 , . . . , x m and a sequence of labels y = y 1 , y 2 , . . . , y m . Each y j is a class label for the j’th token of a word sequence, and is a member of a set ... Inference Algorithm and Its Efficient Approximation Xu Sun † Jun’ichi Tsujii †‡§ † Department of Computer Science, University of Tokyo, Japan ‡ School of Computer Science, Un...

Ngày tải lên: 17/03/2014, 22:20