Báo cáo khoa học: cGMP transport by vesicles from human and mouse erythrocytes potx

... Cfb5p, rat NAP57, and mouse and human dyskerin [1]. These proteins localize in the nucleolus and are involved in a variety of essential cellu- lar functions, including processing and modification ... support and helpful discussions, and to A. Mon- aco for contributing to Drosophila rearing. J. F. de Celis is supported by a grant (BFU2006-06501) from the Spanish Ministry of...

Ngày tải lên: 06/03/2014, 22:21

... production of pyruvate from cysteine by OsiS was measured and found to be approximately 32 nmol pyruvateÆmin )1 Æmg OsiS )1 . Pyruvate can also be produced from cysteine by cyste- ine lyase enzymes ... to that of IscS (Fig. 1A), with a two-domain organization and the presence of both a-helices and b-strands. On the basis of these data and the fact that alr2505-expression is sp...

Ngày tải lên: 18/02/2014, 04:20

... described above are very similar from a regulatory point of view. dCMP deaminase is activa- ted by dCTP and inhibited by dTTP and both nucleo- tides act on the enzyme by binding to an allosteric site to ... represent- ing free and total radioactive nucleotide were washed by TLC in 1 m acetic acid, cut out and quantified by liquid scintillation as above for samples from ki...

Ngày tải lên: 18/02/2014, 16:20

... induced by ligands on C-LytA monitored by near-UV CD with no ligand added (—) and upon addition of ligands: s, d, 2.5 and 20 m M choline; n, m, 2.5 mM and 20 mM atropine; h, j), 2.5 m M and 20 ... min. Experimental con- ditions depended on the enzyme, and were set as follows: 37 °C and pH 6.9 for LytA; 30 °C and pH 6.0 for LytC; and 30 °C and pH 6.9 for Pce. The specific...

Ngày tải lên: 19/02/2014, 05:20

... followed by recruitment of InsP 3 Rs and RyRs by CICR. Although there is much circumstantial evidence from physiologi- cal and pharmacological studies that cholecystokinin increases NAADP and cADPR ... release by cyclic ADP-ribose and calmodulin. J Biol Chem 270, 9060–9066. 7 Galione A (2002) Regulation of synthesis of cADPR and NAADP. In Cyclic ADP-Ribose and NAADP: Struc...

Ngày tải lên: 20/02/2014, 01:20

... Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with ... between arginine and agmatine. Agmatine, which results from decarboxylation of arginine by arginine decarboxylase, is a metabolic intermediate in the biosynthesis of putrescine...

Ngày tải lên: 20/02/2014, 02:21

... (76,739,723 sentences) from the MEDLINE abstracts tokenised by McIn- tosh and Curran (2008). These sentences were POS-tagged and parsed twice, once as for the newswire and Wikipedia data, and then again, ... adapted to suit the parser by train- ing on the combination of these sets and the stan- dard training corpora. We applied standard evalu- ation metrics for speed and acc...

Ngày tải lên: 20/02/2014, 04:20

... Singapore, 4 August 2009. c 2009 ACL and AFNLP Finding Hedges by Chasing Weasels: Hedge Detection Using Wikipedia Tags and Shallow Linguistic Features Viola Ganter and Michael Strube EML Research ... (Lakoff, 1973; Hyland, 1998). Many NLP applications could benefit from identifying linguistic hedges, e.g. question an- swering systems (Riloff et al., 2003), information extraction fr...

Ngày tải lên: 20/02/2014, 09:20

... final GI of the VP reaches a high value. It benefits on the one hand from its own quality (in- dicated by PI) and on another hand from that of its embedded constituents. In the end, the final GI obtained ... characterization and is formed by the subset of the satisfied properties, noted P + , and the set of the violated ones, noted P − . For example, the characterizations associated...

Ngày tải lên: 20/02/2014, 11:21

... text from the Wall Street Journal and the Brown Corpora. Our results from the Wall Street Journal Corpus indicate that with 400 statistically derived constraint rules and about 800 hand-crafted ... average), and corre- sponding testing texts (with about 11,800 words on the average), and then tagged these texts using the statistical rules and hand-crafted con- straints. T...

Ngày tải lên: 20/02/2014, 18:20